Search Results - "HARUTA, Yuro"

Endoglin-targeted cancer therapy by Seon, Ben K, Haba, Akinao, Matsuno, Fumihiko, Takahashi, Norihiko, Tsujie, Masanori, She, Xinwei, Harada, Naoko, Uneda, Shima, Tsujie, Tomoko, Toi, Hirofumi, Tsai, Hilda, Haruta, Yuro

“…Vascular-targeting antiangiogenic therapy (VTAT) of cancer can be advantageous over conventional tumor cell targeted cancer therapy if an appropriate target is…”
Get more information

Induction of Lasting Complete Regression of Preformed Distinct Solid Tumors by Targeting the Tumor Vasculature Using Two New Anti-Endoglin Monoclonal Antibodies by MATSUNO, F, HARUTA, Y, KONDO, M, TSAI, H, BARCOS, M, SEON, B. K

“…Endoglin (EDG, CD105) is a proliferation-associated antigen on endothelial cells. In this study, two new anti-EDG monoclonal antibodies (mAbs) Y4-2F1 (or…”
Get full text

Pneumatosis Cystoides Intestinalis after αGlucosidase Inhibitor Treatment in a Patient with Interstitial Pneumonitis by Hisamoto, Akiko, Mizushima, Takaaki, Sato, Ken, Haruta, Yuro, Tanimoto, Yasushi, Tanimoto, Mitsune, Matsuo, Keisuke

“…A 56yearold woman was admitted to our hospital for treatment of nonspecific interstitial pneumonitis (NSIP). The patient started prednisone treatment, but one…”
Get full text

Pneumatosis Cystoides Intestinalis after .ALPHA.Glucosidase Inhibitor Treatment in a Patient with Interstitial Pneumonitis by Hisamoto, Akiko, Mizushima, Takaaki, Sato, Ken, Haruta, Yuro, Tanimoto, Yasushi, Tanimoto, Mitsune, Matsuo, Keisuke

Get full text

Facilitation of endoglin‐targeting cancer therapy by development/utilization of a novel genetically engineered mouse model expressing humanized endoglin (CD105) by Toi, Hirofumi, Tsujie, Masanori, Haruta, Yuro, Fujita, Kanako, Duzen, Jill, Seon, Ben K.

“…Endoglin (ENG) is a TGF‐β coreceptor and essential for vascular development and angiogenesis. A chimeric antihuman ENG (hENG) monoclonal antibody (mAb) c‐SN6j…”
Get full text

Facilitation of endoglin-targeting cancer therapy by development/utilization of a novel genetically engineered mouse model expressing humanized endoglin (CD105): Vascular Endoglin Targeting Cancer Therapy by Toi, Hirofumi, Tsujie, Masanori, Haruta, Yuro, Fujita, Kanako, Duzen, Jill, Seon, Ben K.

Get full text

Angiogenesis and metastasis marker of human tumors by Seon, B K, Takahashi, N, Haba, A, Matsuno, F, Haruta, Y, She, X W, Harada, N, Tsai, H

“…Tumor growth and metastasis are dependent on angiogenesis. Therefore, certain angiogenesis markers may be useful as metastasis markers and/or the targets for…”
Get more information

Abstract 378: Serum endoglin (CD105): Molecular heterogeneity and marked differences among different anti-endoglin monoclonal antibodies in the detection of metastasis and tumor progression by Harada, Naoko, Takahashi, Norihiko, Haruta, Yuro, Tsai, Hilda, Greco, William, Seon, Ben K.

“…Abstract Endoglin (ENG, CD105) is a proliferation-associated homodimeric cell membrane antigen of endothelial cells and leukemia cells. It is strongly…”
Get full text

Association of serum endoglin with metastasis in patients with colorectal, breast, and other solid tumors, and suppressive effect of chemotherapy on the serum endoglin by TAKAHASHI, Norihiko, KAWANISHI-TABATA, Rika, HABA, Akinao, TABATA, Masahiro, HARUTA, Yuro, TSAI, Hilda, SEON, Ben K

“…In this report, we present data indicating that the increased serum endoglin (EDG; CD105) quantitated by a double-antibody sandwich assay is associated with…”
Get full text

Long-lasting complete inhibition of human solid tumors in SCID mice by targeting endothelial cells of tumor vasculature with antihuman endoglin immunotoxin by SEON, B. K, MATSUNO, F, HARUTA, Y, KONDO, M, BARCOS, M

“…In the present study, we developed an antitumor immunoconjugate that appears to be promising as a novel curative antitumor agent against a variety of human…”
Get full text

Receptor-targeted anticancer therapy by Seon, Ben K., Haruta, Yuro, Matsuno, Fumihiko, Haba, Akinao, Takahashi, Norihiko, She, Xinwei, Harada, Naoko, Uneda, Shima, Tsujie, Masanori, Tsujie, Tomoko, Toi, Hirofumi, Tsai, Hilda

“…ENG is a homodimeric cell membrane glycoprotein that was initially found on human leukemia cells and subsequently on endothelial cells. ENG as a target for…”
Get full text

Antiangiogenic radioimmunotherapy of human solid tumors in SCID mice using125I-labeled anti-endoglin monoclonal antibodies by Tabata, Masahiro, Kondo, Masao, Haruta, Yuro, Seon, Ben K.

Get full text

Association of Serum Endoglin with Metastasis in Patients with Colorectal, Breast, and Other Solid Tumors, and SuppressiveEffect of Chemotherapy on the Serum Endoglin by Norihiko Takahashi, Rika Kawanishi-Tabata, Akinao Haba, Masahiro Tabata, Yuro Haruta, Hilda Tsai, Ben K. Seon

“…In this report, we present data indicating that the increased serum endoglin (EDG; CD105) quantitated by a double-antibody sandwich assay is associated with…”
Get full text

Two cases of unclassified chronic myeloproliferative disorders by Hirano, A, Takahashi, I, Haruta, Y, Nakamura, T, Nakata, H, Yorimitsu, S, Sekito, N, Kimura, I

“…Two cases of unclassified chronic myeloproliferative disorders (UCMPD), diagnosed by hematological, cytogenetic and DNA analyses, are described. Case 1: a 63…”
Get more information

Antiangiogenic radioimmunotherapy of human solid tumors in SCID mice using 125I‐labeled anti‐endoglin monoclonal antibodies by Tabata, Masahiro, Kondo, Masao, Haruta, Yuro, Seon, Ben K.

“…Endoglin (CD105), which is a component of the TGF‐β receptor complex, is highly expressed at the surface of proliferating human endothelial cells such as those…”
Get full text

Distinct Human Leukemia-Associated Cell Surface Glycoprotein GP160 Defined by Monoclonal Antibody SN6 by Haruta, Yuro, Seon, Ben K.

“…In this study, a monoclonal antibody (mAb) termed SN6 was generated by immunizing a mouse with a non-T-cell leukemia antigen preparation isolated from cell…”
Get full text

Efficient transplantation of human non-T-leukemia cells into nude mice and induction of complete regression of the transplanted distinct tumors by ricin A-chain conjugates of monoclonal antibodies SN5 and SN6 by HARA, H, YI LUO, HARUTA, Y, SEON, B. K

“…In the present study, we established a dependable system by which human pre-B- and non-T/non-B-acute lymphoblastic leukemia (ALL) cells are efficiently…”
Get full text

Establishment of ascitic tumor of human pre-B acute lymphoblastic leukemia in nonconditioned nude mice by YI LUO, HARA, H, HARUTA, Y, SEON, B. K

“…In the present study, an ascitic tumor of NALM-6, a human pre-B acute lymphoblastic leukemia cell line, was established in nude mice which had not been…”
Get full text

Production of a monoclonal antibody-bleomycin conjugate utilizing dextran T-40 and the antigen-targeting cytotoxicity of the conjugate by Manabe, Y, Tsubota, T, Haruta, Y, Okazaki, M, Haisa, S, Nakamura, K, Kimura, I

“…Bleomycin (BLM), a potent anticancer glycopeptide antibiotic, was linked covalently to murine monoclonal anti-HLA IgG1 antibody (H-1) with the use of dextran…”
Get more information

Unique epitopes of common acute lymphoblastic leukemia antigen detected by new monoclonal antibodies by MATSUZAKI, H, HARUTA, Y, FUKUKAWA, T, BARCOS, M. P, SEON, B. K

“…In the present study we have generated four new monoclonal antibodies (mAbs), termed SN5, SN5a, SN5b, and SN5c, which are directed toward the human common…”
Get full text