Search Results - "HARTMANN, Arndt"
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Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016
Published in Modern pathology (01-09-2017)“…Tumor budding is a well-established independent prognostic factor in colorectal cancer but a standardized method for its assessment has been lacking. The…”
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The 2022 World Health Organization Classification of Tumors of the Urinary System and Male Genital Organs—Part B: Prostate and Urinary Tract Tumors
Published in European urology (01-11-2022)“…The fifth edition of the World Health Organization (WHO) “Blue Book” brings a comprehensive update on the terminology, epidemiology, pathogenesis,…”
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Deep Learning Predicts Molecular Subtype of Muscle-invasive Bladder Cancer from Conventional Histopathological Slides
Published in European urology (01-08-2020)“…Muscle-invasive bladder cancer (MIBC) is the second most common genitourinary malignancy, and is associated with high morbidity and mortality. Recently,…”
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Vascular occlusion by neutrophil extracellular traps in COVID-19
Published in EBioMedicine (01-08-2020)“…Coronavirus induced disease 2019 (COVID-19) can be complicated by severe organ damage leading to dysfunction of the lungs and other organs. The processes that…”
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IL-9 and its receptor are predominantly involved in the pathogenesis of UC
Published in Gut (01-05-2015)“…Several pathogenic roles attributed over the past two decades to either T helper (Th)1 or Th2 cells are increasingly becoming associated with interleukin…”
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Multispectral Optoacoustic Tomography for Assessment of Crohn’s Disease Activity
Published in The New England journal of medicine (30-03-2017)“…A preliminary study suggests that intestinal-wall assessment by means of noninvasive multispectral optoacoustic tomography may distinguish remission from…”
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Tumor Regression Grading After Preoperative Chemoradiotherapy as a Prognostic Factor and Individual-Level Surrogate for Disease-Free Survival in Rectal Cancer
Published in JNCI : Journal of the National Cancer Institute (01-12-2017)“…We investigated tumor regression grading (TRG) as a prognostic marker and individual-level surrogate for disease-free survival (DFS) in patients with rectal…”
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Pathology and systemic therapy of non-clear cell renal cell carcinoma: an overview
Published in Expert review of anticancer therapy (02-11-2021)“…Introduction: Non-clear cell renal cell carcinoma (nccRCC) represents a highly heterogenous group of kidney cancer entities. As most clinical trials…”
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Reduced Expression of miRNA-27a Modulates Cisplatin Resistance in Bladder Cancer by Targeting the Cystine/Glutamate Exchanger SLC7A11
Published in Clinical cancer research (01-04-2014)“…Resistance to cisplatin-based chemotherapy is a major obstacle to bladder cancer treatment. We aimed to identify microRNAs (miRNA) that are dysregulated in…”
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Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands
Published in Nature communications (21-01-2019)“…The molecular pathogenesis of salivary gland acinic cell carcinoma (AciCC) is poorly understood. The secretory Ca-binding phosphoprotein (SCPP) gene cluster at…”
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Misleading Germ Cell Phenotype in Pulmonary NUT Carcinoma Harboring the ZNF532-NUTM1 Fusion
Published in The American journal of surgical pathology (01-02-2022)“…NUT carcinoma (aka NUT midline carcinoma) is a rare, still significantly underrecognized aggressive malignancy. Although historically considered a midline…”
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Ki67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatment
Published in BMC cancer (14-11-2011)“…The pathological complete response (pCR) after neoadjuvant chemotherapy is a surrogate marker for a favorable prognosis in breast cancer patients. Factors…”
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Nuclear NR4A3 Immunostaining Is a Specific and Sensitive Novel Marker for Acinic Cell Carcinoma of the Salivary Glands
Published in The American journal of surgical pathology (01-09-2019)“…Recently, we discovered the recurrent genomic rearrangement [t(4;9)(q13;q31)] enabling upregulation of the transcription factor Nuclear Receptor Subfamily 4…”
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Molecular Characterization of Upper Tract Urothelial Carcinoma in the Era of Next-generation Sequencing: A Systematic Review of the Current Literature
Published in European urology (01-08-2020)“…While upper tract urothelial carcinoma (UTUC) share histological appearance with bladder cancer (BC), the former has differences in etiology and clinical…”
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Complement Activation via the Lectin and Alternative Pathway in Patients With Severe COVID-19
Published in Frontiers in immunology (02-02-2022)“…Complement plays an important role in the direct defense to pathogens, but can also activate immune cells and the release of pro-inflammatory cytokines…”
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Pancreatic undifferentiated rhabdoid carcinoma: KRAS alterations and SMARCB1 expression status define two subtypes
Published in Modern pathology (01-02-2015)“…Pancreatic undifferentiated carcinoma is a heterogeneous group of neoplasms, including pleomorphic giant cell, sarcomatoid, round cell, and rhabdoid…”
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WHO 2022 landscape of papillary and chromophobe renal cell carcinoma
Published in Histopathology (01-10-2022)“…The 5th edition of the WHO Classification of Tumours of the Urinary and Male Genital Systems contains relevant revisions and introduces a group of molecularly…”
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SMARCA4 and SMARCA2 Deficiency in Non-small Cell Lung Cancer: Immunohistochemical Survey of 316 Consecutive Specimens
Published in Annals of diagnostic pathology (01-02-2017)“…Abstract The chromatin remodeling Switch Sucrose Non-Fermentable (SWI/SNF) complex has been increasingly implicated in the pathogenesis and dedifferentiation…”
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Eosinophilic vacuolated tumor (EVT) of kidney demonstrates sporadic TSC/MTOR mutations: next-generation sequencing multi-institutional study of 19 cases
Published in Modern pathology (01-03-2022)“…A distinct renal tumor has recently been described as “high-grade oncocytic renal tumor” and “sporadic renal cell carcinoma with eosinophilic and vacuolated…”
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