Search Results - "HARTMAN, J. J"

Artificial intelligence as the next step towards precision pathology by Acs, B., Rantalainen, M., Hartman, J.

“…Pathology is the cornerstone of cancer care. The need for accuracy in histopathologic diagnosis of cancer is increasing as personalized cancer therapy requires…”
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Review of the Safety and Efficacy of Moringa oleifera by Stohs, Sidney J., Hartman, Michael J.

“…Moringa oleifera leaves, seeds, bark, roots, sap, and flowers are widely used in traditional medicine, and the leaves and immature seed pods are used as food…”
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Mechanistic and structural basis for activation of cardiac myosin force production by omecamtiv mecarbil by Planelles-Herrero, Vicente J., Hartman, James J., Robert-Paganin, Julien, Malik, Fady I., Houdusse, Anne

“…Omecamtiv mecarbil is a selective, small-molecule activator of cardiac myosin that is being developed as a potential treatment for heart failure with reduced…”
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Improved breast cancer histological grading using deep learning by Wang, Y., Acs, B., Robertson, S., Liu, B., Solorzano, L., Wählby, C., Hartman, J., Rantalainen, M.

“…The Nottingham histological grade (NHG) is a well-established prognostic factor for breast cancer that is broadly used in clinical decision making. However,…”
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A Practical Guide to Whole Slide Imaging: A White Paper From the Digital Pathology Association by Zarella, Mark D, Bowman, Douglas, Aeffner, Famke, Farahani, Navid, Xthona, Albert, Absar, Syeda Fatima, Parwani, Anil, Bui, Marilyn, Hartman, Douglas J

“…Whole slide imaging (WSI) represents a paradigm shift in pathology, serving as a necessary first step for a wide array of digital tools to enter the field. Its…”
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Ablation of sensory neurons in a genetic model of pancreatic ductal adenocarcinoma slows initiation and progression of cancer by Saloman, Jami L., Albers, Kathryn M., Li, Dongjun, Hartman, Douglas J., Crawford, Howard C., Muha, Emily A., Rhim, Andrew D., Davis, Brian M.

“…Pancreatic ductal adenocarcinoma (PDAC) is characterized by an exuberant inflammatory desmoplastic response. The PDAC microenvironment is complex, containing…”
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Patterns of Fitbit Use and Activity Levels Throughout a Physical Activity Intervention: Exploratory Analysis from a Randomized Controlled Trial by Hartman, Sheri J, Nelson, Sandahl H, Weiner, Lauren S

“…There has been a rapid increase in the use of technology-based activity trackers to promote behavior change. However, little is known about how individuals use…”
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A meta-analytic examination of the potential correlates and consequences of workload by Bowling, Nathan A., Alarcon, Gene M., Bragg, Caleb B., Hartman, Michael J.

“…Over the last four decades, occupational stress researchers have given considerable attention to the potential correlates and consequences of workload. In the…”
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Intermittent Fasting and Human Metabolic Health by Patterson, Ruth E., PhD, Laughlin, Gail A., PhD, LaCroix, Andrea Z., PhD, Hartman, Sheri J., PhD, Natarajan, Loki, PhD, Senger, Carolyn M., MD, Martínez, María Elena, PhD, Villaseñor, Adriana, PhD, Sears, Dorothy D., PhD, Marinac, Catherine R, Gallo, Linda C., PhD

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PHOTOMETRIC STUDY ON STELLAR MAGNETIC ACTIVITY. I. FLARE VARIABILITY OF RED DWARF STARS IN THE OPEN CLUSTER M37 by Chang, S.-W., Byun, Y.-I., Hartman, J. D.

“…ABSTRACT Based on one-month long MMT time-series observations of the open cluster M37, we monitored light variations of nearly 2500 red dwarfs and successfully…”
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Circumstantial and constitutive moral luck in Kant's moral philosophy by Hartman, Robert J.

“…The received view of Kant's moral philosophy is that it precludes all moral luck. But I offer a plausible interpretation according to which Kant embraces moral…”
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Introduction to Digital Image Analysis in Whole-slide Imaging: A White Paper from the Digital Pathology Association by Aeffner, Famke, Zarella, Mark D., Buchbinder, Nathan, Bui, Marilyn M., Goodman, Matthew R., Hartman, Douglas J., Lujan, Giovanni M., Molani, Mariam A., Parwani, Anil V., Lillard, Kate, Turner, Oliver C., Vemuri, Venkata N.P., Yuil-Valdes, Ana G., Bowman, Douglas

“…The advent of whole-slide imaging in digital pathology has brought about the advancement of computer-aided examination of tissue via digital image analysis…”
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Explained Variance Measures for Multilevel Models by LaHuis, David M., Hartman, Michael J., Hakoyama, Shotaro, Clark, Patrick C.

“…One challenge in using multilevel models is determining how to report the amount of explained variance. In multilevel models, explained variance can be…”
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Identifying tumor in pancreatic neuroendocrine neoplasms from Ki67 images using transfer learning by Niazi, Muhammad Khalid Khan, Tavolara, Thomas Erol, Arole, Vidya, Hartman, Douglas J, Pantanowitz, Liron, Gurcan, Metin N

“…The World Health Organization (WHO) has clear guidelines regarding the use of Ki67 index in defining the proliferative rate and assigning grade for pancreatic…”
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Interplay of mitochondrial fission-fusion with cell cycle regulation: Possible impacts on stem cell and organismal aging by Spurlock, B., Tullet, JMA, Hartman, J.L., Mitra, K.

“…Declining mitochondrial function and homeostasis is a hallmark of aging. It is appreciated that the role of mitochondria is much more complex than generating…”
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Characterization of two classes of small molecule inhibitors of Arp2/3 complex by Pollard, T. D, Nolen, B. J, Tomasevic, N, Russell, A, Pierce, D. W, Jia, Z, McCormick, C. D, Hartman, J, Sakowicz, R

“…Polymerization of actin filaments directed by the actin-related protein (Arp)2/3 complex supports many types of cellular movements. However, questions remain…”
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An Exploratory Study of Physical Therapists From High-Income Countries Practising Outside of Their Scope in Low and Middle-Income Countries by Hartman, J., Dholakia, K.

“…Purpose To quantify how often physical therapists from high-income countries (HIC) travelling to low- and middle-income countries (LMIC) practise outside their…”
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Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy by Dragovich, Peter S, Pillow, Thomas H, Blake, Robert A, Sadowsky, Jack D, Adaligil, Emel, Adhikari, Pragya, Chen, Jinhua, Corr, Nicholas, dela Cruz-Chuh, Josefa, Del Rosario, Geoffrey, Fullerton, Aaron, Hartman, Steven J, Jiang, Fan, Kaufman, Susan, Kleinheinz, Tracy, Kozak, Katherine R, Liu, Liling, Lu, Ying, Mulvihill, Melinda M, Murray, Jeremy M, O’Donohue, Aimee, Rowntree, Rebecca K, Sawyer, William S, Staben, Leanna R, Wai, John, Wang, Jian, Wei, BinQing, Wei, Wentao, Xu, Zijin, Yao, Hui, Yu, Shang-Fan, Zhang, Donglu, Zhang, Hongyan, Zhang, Shenhua, Zhao, Yongxin, Zhou, Hao, Zhu, Xiaoyu

“…Heterobifunctional compounds that direct the ubiquitination of intracellular proteins in a targeted manner via co-opted ubiquitin ligases have enormous…”
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Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties by Dragovich, Peter S, Pillow, Thomas H, Blake, Robert A, Sadowsky, Jack D, Adaligil, Emel, Adhikari, Pragya, Bhakta, Sunil, Blaquiere, Nicole, Chen, Jinhua, dela Cruz-Chuh, Josefa, Gascoigne, Karen E, Hartman, Steven J, He, Mingtao, Kaufman, Susan, Kleinheinz, Tracy, Kozak, Katherine R, Liu, Liang, Liu, Liling, Liu, Qi, Lu, Ying, Meng, Fanwei, Mulvihill, Melinda M, O’Donohue, Aimee, Rowntree, Rebecca K, Staben, Leanna R, Staben, Steven T, Wai, John, Wang, Jian, Wei, BinQing, Wilson, Catherine, Xin, Jianfeng, Xu, Zijin, Yao, Hui, Zhang, Donglu, Zhang, Hongyan, Zhou, Hao, Zhu, Xiaoyu

“…The biological and medicinal impacts of proteolysis-targeting chimeras (PROTACs) and related chimeric molecules that effect intracellular degradation of target…”
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HAT-P-32b and HAT-P-33b: Two Highly Inflated Hot Jupiters Transiting High-jitter Stars by Hartman, J. D, Bakos, G. Á, Torres, G, Latham, D. W, Kovács, Géza, Béky, B, Quinn, S. N, Mazeh, T, Shporer, A, Marcy, G. W, Howard, A. W, Fischer, D. A, Johnson, J. A, Esquerdo, G. A, Noyes, R. W, Sasselov, D. D, Stefanik, R. P, Fernandez, J. M, Szklenár, T, Lázár, J, Papp, I, Sári, P

“…We report the discovery of two exoplanets transiting high-jitter stars. HAT-P-32b orbits the bright V = 11.289 late-F-early-G dwarf star GSC 3281-00800, with a…”
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