Search Results - "HARRINGTON, William J"

Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells by Obeng, Esther A., Carlson, Louise M., Gutman, Delia M., Harrington, William J., Lee, Kelvin P., Boise, Lawrence H.

“…Multiple myeloma (MM) is an incurable plasma cell malignancy. The 26S proteasome inhibitor, bortezomib, selectively induces apoptosis in MM cells; however, the…”
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EBV MicroRNAs in Primary Lymphomas and Targeting of CXCL-11 by ebv-mir-BHRF1-3 by TIANLI XIA, O'HARA, Andrea, TOOMEY, Ngoc L, BRITES, Carlos, DITTMER, Dirk P, HARRINGTON, William J, ARAUJO, Iguaracyra, BARRETO, Jose, CARVALHO, Eny, BAHIA SAPUCAIA, Jose, RAMOS, Juan Carlos, LUZ, Estela, PEDROSO, Celia, MANRIQUE, Michele

“…EBV-encoded microRNAs (miRNAs) have been identified and their functions are being studied. The expression pattern of these miRNAs in clinical samples of…”
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Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling by Sin, Sang-Hoon, Roy, Debasmita, Wang, Ling, Staudt, Michelle R., Fakhari, Farnaz D., Patel, Dhavalkumar D., Henry, David, Harrington, William J., Damania, Blossom A., Dittmer, Dirk P.

“…The antitumor potency of the mTOR inhibitor rapamycin (sirolimus) is the subject of intense investigations. Primary effusion lymphoma (PEL) appears as an…”
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Tumor suppressor microRNAs are underrepresented in primary effusion lymphoma and Kaposi sarcoma by O'Hara, Andrea J., Wang, Ling, Dezube, Bruce J., Harrington, William J., Damania, Blossom, Dittmer, Dirk P.

“…The presence of tumor-specific microRNAs reflects tissue of origin and tumor stage. We show that the absence of miRNAs likewise can be used to determine tumor…”
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Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Interacts with Bromodomain Protein Brd4 on Host Mitotic Chromosomes by JIANXIN YOU, SRINIVASAN, Viswanathan, DENIS, Gerald V, HARRINGTON, William J, BALLESTAS, Mary E, KAYE, Kenneth M, HOWLEY, Peter M

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Distinct Subsets of Primary Effusion Lymphoma Can Be Identified Based on Their Cellular Gene Expression Profile and Viral Association by WEN FAN, BUBMAN, Darya, CHADBURN, Amy, HARRINGTON, William J, CESARMAN, Ethel, KNOWLES, Daniel M

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Pre-micro RNA signatures delineate stages of endothelial cell transformation in Kaposi sarcoma by O'Hara, Andrea J, Chugh, Pauline, Wang, Ling, Netto, Eduardo M, Luz, Estrella, Harrington, William J, Dezube, Bruce J, Damania, Blossom, Dittmer, Dirk P

“…MicroRNAs (miRNA) have emerged as key regulators of cell lineage differentiation and cancer. We used precursor miRNA profiling by a novel real-time QPCR method…”
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Apoptosis: Programmed cell death at a molecular level by Schultz, Duane R., Harringto, William J.

“…Objectives: To characterize cell surface receptors, their ligands, and their proteins in the 2 major pathways of apoptosis; the components that…”
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BCL6, MUM1, and CD10 expression in mantle cell lymphoma by Gualco, Gabriela, Weiss, Lawrence M, Harrington, Jr, William J, Bacchi, Carlos E

“…Mantle cell lymphoma (MCL) characteristically express CD20, CD5, and cyclin-D1, carries the translocation t(11;14) (q13;q32) and typically has no expression of…”
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Nodal Diffuse Large B-cell Lymphomas in Children and Adolescents: Immunohistochemical Expression Patterns and c-MYC Translocation in Relation to Clinical Outcome by GUALCO, Gabriela, WEISS, Lawrence M, HARRINGTON, William J, BACCHI, Carlos E

“…Diffuse large B-cell lymphoma (DLBCL) is a very infrequent neoplasm in the pediatric age group; therefore there are very few studies on the immunophenotype or…”
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Frequent expression of multiple myeloma 1/interferon regulatory factor 4 in Burkitt lymphoma by Gualco, Gabriela, MD, Queiroga, Eduardo M., MD, Weiss, Lawrence M., MD, Klumb, Claudete E.N., MD, Harrington, William J., MD, Bacchi, Carlos E., MD

“…Summary Burkitt lymphoma is a highly aggressive non-Hodgkin lymphoma with endemic, sporadic, and immunodeficiency-associated clinical variants composed of…”
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HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP/p300 coactivators by RONGTUAN LIN, GENIN, Pierre, MAMANE, Yael, SGARBANTI, Marco, BATTISTINI, Angela, HARRINGTON, William J, BARBER, Glen N, HISCOTT, John

“…Human herpes virus 8 (HHV-8) has developed unique mechanisms for altering cellular proliferative and apoptotic control pathways by incorporating viral homologs…”
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IRF-4 and c-Rel expression in antiviral-resistant adult T-cell leukemia/lymphoma by Ramos, Juan Carlos, Ruiz, Phillip, Ratner, Lee, Reis, Isildinha M., Brites, Carlos, Pedroso, Celia, Byrne, Gerald E., Toomey, Ngoc L., Andela, Valentine, Harhaj, Edward W., Lossos, Izidore S., Harrington, William J.

“…Adult T-cell leukemia/lymphoma (ATLL) is a generally fatal malignancy. Most ATLL patients fare poorly with conventional chemotherapy; however, antiviral…”
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Development of an Immunofluorescence Assay Using Recombinant Proteins Expressed in Insect Cells To Screen and Confirm Presence of Human Herpesvirus 8-Specific Antibodies by Minhas, Veenu, Crosby, Lynsey N, Crabtree, Kay L, Phiri, Saul, M'soka, Tendai J, Kankasa, Chipepo, Harrington, William J, Mitchell, Charles D, Wood, Charles

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Primary and secondary T-cell lymphomas of the breast: clinico-pathologic features of 11 cases by Gualco, Gabriela, Chioato, Lucimara, Harrington, Jr, William J, Weiss, Lawrence M, Bacchi, Carlos E

“…Breast involvement by non-Hodgkin lymphomas is rare, and exceptional for T-cell lymphomas; we studied the morphologic, immunophenotypic, and clinical features…”
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Burkitt Lymphoma in Brazil Is Characterized by Geographically Distinct Clinicopathologic Features by QUEIROGA, Eduardo M, GUALCO, Gabriela, WEISS, Lawrence M, DITTMER, Dirk P, ARAUJO, Iguaracyra, KLUMB, Claudette E. N, HARRINGTON, William J, BACCHI, Carlos E

“…Burkitt lymphoma (BL) is a highly aggressive non-Hodgkin lymphoma with a consistent MYC translocation. Epstein-Barr virus (EBV) has been associated with BL at…”
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Deregulated expression of CD40 ligand in HTLV-I infection: Distinct mechanisms of downregulation in HTLV-I-transformed cell lines and ATL patients by Harhaj, Nicole S, Janic, Branislava, Ramos, Juan C, Harrington, William J, Harhaj, Edward W

“…Abstract HTLV-I infection is associated with the development of adult T cell leukemia (ATL) and the neuroinflammatory disease HAM/TSP. There are quantitative…”
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Induction of a TRAIL mediated suicide program by interferon alpha in primary effusion lymphoma by TOOMEY, Ngoc L, DEYEV, Vadim V, WOOD, Charles, BOISE, Lawrence H, SCOTT, Duncan, LEI HUA LIU, CABRAL, Lisa, PODACK, Eckhard R, BARBER, Glen N, HARRINGTON, William J

“…Gammaherpes viruses are often detected in lymphomas arising in immunocompromised patients. We have found that Azidothymidine (AZT) alone induces apoptosis in…”
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Potentiation of TRAIL-induced apoptosis in primary effusion lymphoma through azidothymidine-mediated inhibition of NF-κB by Ghosh, Subrata K., Wood, Charles, Boise, Lawrence H., Mian, Abdul M., Deyev, Vadim V., Feuer, Gerold, Toomey, Ngoc L., Shank, Nicole C., Cabral, Lisa, Barber, Glen N., Harrington, William J.

“…The survival of viral mediated lymphomas depends upon constitutive nuclear factor kappa B (NF-κB) activity. AIDS-related human herpesvirus type 8–associated…”
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Analysis of Human T-Cell Lymphotropic Virus in CD25+ Anaplastic Large Cell Lymphoma in Children by GUALCO, Gabriela, CHIOATO, Lucimara, WEISS, Lawrence M, HARRINGTON, William J, BACCHI, Carlos E

“…Anaplastic large cell lymphoma (ALCL) is recognized as 2 distinct diseases: anaplastic lymphoma kinase (ALK)+ ALCL and ALK- ALCL. ALK+ ALCL occurs in younger…”
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