Search Results - "HAROON, Zishan A"

A Novel Role for Erythropoietin During Fibrin-Induced Wound-Healing Response by Haroon, Zishan A., Amin, Khalid, Jiang, Xiaohong, Arcasoy, Murat O.

“…In this study, we investigated the role of the hematopoietic cytokine erythropoietin (EPO) during wound healing, the physiological response to tissue injury…”
Get full text

Erythropoietin and Erythropoietin Receptor Expression in Head and Neck Cancer: Relationship to Tumor Hypoxia by ARCASOY, Murat O, AMIN, Khalid, CHOU, Shu-Chuan, HAROON, Zishan A, VARIA, Mahesh, RALEIGH, James A

“…Purpose: Erythropoietin, an oxygen-regulated glycoprotein hormone, is a hematopoietic cytokine that stimulates erythropoiesis by binding to its cellular…”
Get full text

Functional Significance of Erythropoietin Receptor Expression in Breast Cancer by Arcasoy, Murat O, Amin, Khalid, Karayal, Aysen F, Chou, Shu-Chuan, Raleigh, James A, Varia, Mahesh A, Haroon, Zishan A

“…Erythropoietin (EPO) is the principal hematopoietic cytokine that regulates mammalian erythropoiesis by binding to its transmembrane receptor EpoR. Recent…”
Get full text

Radiation-induced hypoxia may perpetuate late normal tissue injury by Vujaskovic, Z, Anscher, M S, Feng, Q F, Rabbani, Z N, Amin, K, Samulski, T S, Dewhirst, M W, Haroon, Z A

“…The purpose of this study was to determine whether or not hypoxia develops in rat lung tissue after radiation. Fisher-344 rats were irradiated to the right…”
Get more information

Tie2 Expression and Phosphorylation in Angiogenic and Quiescent Adult Tissues by Wong, Adrianne L, Haroon, Zishan A, Werner, Sabine, Dewhirst, Mark W, Greenberg, Charles S, Peters, Kevin G

“…Angiogenesis, the process of new vessels sprouting from the existing vasculature, is a critical process during early development. However, angiogenesis rarely…”
Get full text

The metal-responsive transcription factor-1 protein is elevated in human tumors by Shi, Yihui, Amin, Khalid, Sato, Barbara G., Samuelsson, Steven J., Sambucetti, Lidia, Haroon, Zishan A., Laderoute, Keith, Murphy, Brian J.

“…We previously identified metal-responsive transcription factor-1 (MTF-1) as a positive contributor to mouse fibrosarcoma growth through effects on cell…”
Get full text

The relationship between hypoxia and angiogenesis by Moeller, Benjamin J, Cao, Yiting, Vujaskovic, Zeljko, Li, Chuan Y, Haroon, Zishan A, Dewhirst, Mark W

“…Recent studies have generated a large amount of data supporting the hypothesis that hypoxia drives tumor angiogenesis. The relationship between the two is…”
Get full text

Erythropoietin and erythropoietin receptor expression in human prostate cancer by Arcasoy, Murat O, Amin, Khalid, Vollmer, Robin T, Jiang, Xiaohong, Demark-Wahnefried, Wendy, Haroon, Zishan A

“…Erythropoietin is a hematopoietic cytokine that regulates the production of red blood cells. Erythropoietin is normally produced in the adult kidney in a…”
Get full text

Review of methods used to study oxygen transport at the microcirculatory level by Dewhirst, Mark W., Klitzman, Bruce, Braun, Rod D., Brizel, David M., Haroon, Zishan A., Secomb, Timothy W.

“…The existence of hypoxic regions in tumors has long been recognized as a key factor leading to radiation resistance. More recently, it has been found that low…”
Get full text

Loss of metal transcription factor‐1 suppresses tumor growth through enhanced matrix deposition by Haroon, Zishan A., Amin, Khalid, Lichtlen, Peter, Sato, Barbara, Huynh, Nhung T., Wang, Zhaohui, Schaffner, Walter, Murphy, Brian J.

“…ABSTRACT Metal transcription factor‐1 (MTF‐1) is a ubiquitous transcriptional regulator and chromatin in‐ sulator with roles in cellular stress responses and…”
Get full text

Particle Replication in Nonwetting Templates Nanoparticles with Tumor Selective Alkyl Silyl Ether Docetaxel Prodrug Reduces Toxicity by Chu, Kevin S, Finniss, Mathew C, Schorzman, Allison N, Kuijer, Jennifer L, Luft, J. Christopher, Bowerman, Charles J, Napier, Mary E, Haroon, Zishan A, Zamboni, William C, DeSimone, Joseph M

“…Delivery systems designed to have triggered release after passively targeting the tumor may improve small molecule chemotherapeutic delivery. Particle…”
Get full text

Localization of Tissue Transglutaminase in Human Carotid and Coronary Artery Atherosclerosis: Implications for Plaque Stability and Progression by Haroon, Zishan A, Wannenburg, Thomas, Gupta, Madhu, Greenberg, Charles S, Wallin, Reidar, Sane, David C

“…Although atherosclerosis progresses in an indolent state for decades, the rupture of plaques creates acute ischemic syndromes that may culminate in myocardial…”
Get full text

Endothelial cell-surface tissue transglutaminase inhibits neutrophil adhesion by binding and releasing nitric oxide by Lai, Thung-S., Lindberg, Robert A., Zhou, Hua-Lin, Haroon, Zishan A., Dewhirst, Mark W., Hausladen, Alfred, Juang, Y.-L., Stamler, Jonathan S., Greenberg, Charles S.

“…Nitric oxide (NO) produced by endothelial cells in response to cytokines displays anti-inflammatory activity by preventing the adherence, migration and…”
Get full text

Dietary Glycine Inhibits Angiogenesis During Wound Healing and Tumor Growth by Amin, Khalid, Li, Jie, Chao, Wan Ru, Dewhirst, Mark W., Haroon, Zishan A.

“…In this study we investigated the effects of glycine on angiogenesis during embryogenesis, wound healing and tumor growth. In chorioallantoic membrane (CAM)…”
Get full text

Transcriptional Response to Hypoxia in Human Tumors by Lal, Anita, Peters, Hans, St. Croix, Brad, Haroon, Zishan A., Dewhirst, Mark W., Strausberg, Robert L., Kaanders, Johannes H. A. M., van der Kogel, Albert J., Riggins, Gregory J.

“…Background: The presence of hypoxic regions within solid tumors is associated with a more malignant tumor phenotype and worse prognosis. To obtain a blood…”
Get full text

Expression of erythropoietin receptor splice variants in human cancer by Arcasoy, Murat O, Jiang, Xiaohong, Haroon, Zishan A

“…Erythropoietin (EPO) regulates mammalian erythropoiesis by binding to its transmembrane receptor EPOR. Recent studies demonstrated functional EPOR expression…”
Get full text

Tissue transglutaminase is expressed, active, and directly involved in rat dermal wound healing and angiogenesis by Haroon, Zishan A., Hettasch, Joann M., Lai, Thung‐Shenq, Dewhirst, Mark W., Greenberg, Charles S.

“…ABSTRACTTissue transglutaminase (TG) is an enzyme that stabilizes the structure of tissues by covalently ligating extracellular matrix molecules. Expression…”
Get full text

Effect of flaxseed supplementation on prostatic carcinoma in transgenic mice by Lin, Xu, Gingrich, Jeffrey R, Bao, Wenjun, Li, Jie, Haroon, Zishan A, Demark-Wahnefried, Wendy

“…To investigate the effects of flaxseed supplementation on prostatic neoplasia in the transgenic adenocarcinoma mouse prostate (TRAMP) model. A total of 135…”
Get full text

Early wound healing exhibits cytokine surge without evidence of hypoxia by HAROON, Z. A, RALEIGH, J. A, GREENBERG, C. S, DEWHIRST, M. W

“…To ascertain the spatial and temporal relation of wound hypoxia to the cell types involved, expression of selected angiogenic cytokines, the proliferative…”
Get full text

Tissue gradients of energy metabolites mirror oxygen tension gradients in a rat mammary carcinoma model by Walenta, S, Snyder, S, Haroon, Z A, Braun, R D, Amin, K, Brizel, D, Mueller-Klieser, W, Chance, B, Dewhirst, M W

“…It has been shown that oxygen gradients exist in R3230AC tumors grown in window chambers. The fascial surface is better oxygenated than the tumor surface. The…”
Get more information