Search Results - "HARO, Diego"
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Nutritional Regulation of Gene Expression: Carbohydrate-, Fat- and Amino Acid-Dependent Modulation of Transcriptional Activity
Published in International journal of molecular sciences (19-03-2019)“…The ability to detect changes in nutrient levels and generate an adequate response to these changes is essential for the proper functioning of living…”
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2
Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation
Published in Biochemical journal (01-04-2012)“…Nutrient deprivation or starvation frequently correlates with amino acid limitation. Amino acid starvation initiates a signal transduction cascade starting…”
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3
Metabolic Impact of Flavonoids Consumption in Obesity: From Central to Peripheral
Published in Nutrients (10-08-2020)“…The prevention and treatment of obesity is primary based on the follow-up of a healthy lifestyle, which includes a healthy diet with an important presence of…”
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4
Fibroblast Growth Factor 21 and the Adaptive Response to Nutritional Challenges
Published in International journal of molecular sciences (21-09-2019)“…The Fibroblast Growth Factor 21 (FGF21) is considered an attractive therapeutic target for obesity and obesity-related disorders due to its beneficial effects…”
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5
Different fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer
Published in BMC cancer (06-07-2012)“…Fatty acid synthase (FASN) is overexpressed and hyperactivated in several human carcinomas, including lung cancer. We characterize and compare the anti-cancer…”
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6
FGF21 mediates the lipid metabolism response to amino acid starvation
Published in Journal of lipid research (01-07-2013)“…Lipogenic gene expression in liver is repressed in mice upon leucine deprivation. The hormone fibroblast growth factor 21 (FGF21), which is critical to the…”
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7
A low‐protein diet induces body weight loss and browning of subcutaneous white adipose tissue through enhanced expression of hepatic fibroblast growth factor 21 (FGF21)
Published in Molecular nutrition & food research (01-08-2017)“…Scope Fibroblast growth factor 21 (FGF21) is considered a promising therapeutic candidate for the treatment of obesity. Since FGF21 production is regulated by…”
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8
Psychosocial impact of the COVID-19 outbreak and lockdown on Spanish oncological patients: a quantitative approach
Published in Journal of psychosocial oncology (04-05-2021)“…This study analyses the levels of distress and related psychosocial factors among cancer patients during the Spanish lockdown due to COVID-19. A total of 2,779…”
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9
Novel Inhibitors of Fatty Acid Synthase with Anticancer Activity
Published in Clinical cancer research (15-12-2009)“…Purpose: Fatty acid synthase (FASN) is overexpressed in human breast carcinoma. The natural polyphenol (−)-epigallocatechin-3-gallate blocks in vitro FASN…”
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10
Regulation of human class I alcohol dehydrogenases by bile acids
Published in Journal of lipid research (01-09-2013)“…Class I alcohol dehydrogenases (ADH1s) are the rate-limiting enzymes for ethanol and vitamin A (retinol) metabolism in the liver. Because previous studies have…”
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11
Fsp27/CIDEC is a CREB target gene induced during early fasting in liver and regulated by FA oxidation rate
Published in Journal of lipid research (01-03-2013)“…FSP27 [cell death-inducing DFFA-like effector c (CIDEC) in humans] is a protein associated with lipid droplets that downregulates the fatty acid oxidation…”
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12
A Mixture of Pure, Isolated Polyphenols Worsens the Insulin Resistance and Induces Kidney and Liver Fibrosis Markers in Diet-Induced Obese Mice
Published in Antioxidants (05-01-2022)“…Obesity is a worldwide epidemic with severe metabolic consequences. Polyphenols are secondary metabolites in plants and the most abundant dietary antioxidants,…”
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13
Knowledge, Compliance, and Inequities in Colon Cancer Screening in Spain: An Exploratory Study
Published in Healthcare (Basel) (01-09-2023)“…In Spain, inequities exist in implementing colorectal cancer (CRC) tests with the target population-adults aged 50 to 69-as part of population-based CRC…”
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14
Lyophilized Maqui ( Aristotelia chilensis ) Berry Induces Browning in the Subcutaneous White Adipose Tissue and Ameliorates the Insulin Resistance in High Fat Diet-Induced Obese Mice
Published in Antioxidants (01-09-2019)“…Maqui ( ) berry features a unique profile of anthocyanidins that includes high amounts of delphinidin-3-O-sambubioside-5-O-glucoside and…”
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15
Lyophilized Maqui ( Aristotelia chilensis ) Berry Administration Suppresses High-Fat Diet-Induced Liver Lipogenesis through the Induction of the Nuclear Corepressor SMILE
Published in Antioxidants (21-04-2021)“…The liver is one of the first organs affected by accumulated ectopic lipids. Increased de novo lipogenesis and excessive triglyceride accumulation in the liver…”
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An Intronic Peroxisome Proliferator-activated Receptor-binding sequence Mediates Fatty Acid Induction of the Human Carnitine Palmitoyltransferase 1A
Published in Journal of molecular biology (09-12-2005)“…The liver plays a central role in the response to fasting. The hormonal profile in this condition, low insulin, and high concentrations of glucagon in plasma,…”
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Ketogenic HMGCS2 Is a c-Myc Target Gene Expressed in Differentiated Cells of Human Colonic Epithelium and Down-Regulated in Colon Cancer
Published in Molecular cancer research (01-09-2006)“…HMGCS2 , the gene that regulates ketone body production, is expressed in liver and several extrahepatic tissues, such as the colon. In CaCo-2 colonic…”
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18
Green Tea Catechin Inhibits Fatty Acid Synthase without Stimulating Carnitine Palmitoyltransferase-1 or Inducing Weight Loss in Experimental Animals
Published in Anticancer research (01-11-2008)“…Background: The enzyme fatty acid synthase (FASN) is highly expressed in many human carcinomas and its inhibition is cytotoxic to human cancer cells. The use…”
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Control of Human Muscle-type Carnitine Palmitoyltransferase I Gene Transcription by Peroxisome Proliferator-activated Receptor
Published in The Journal of biological chemistry (10-04-1998)“…The expression of several genes involved in intra- and extracellular lipid metabolism, notably those involved in peroxisomal and mitochondrial β-oxidation, is…”
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20
Cranial anatomy of Acynodon adriaticus and extreme durophagous adaptations in Eusuchia (Reptilia: Crocodylomorpha)
Published in Anatomical record (Hoboken, N.J. : 2007) (01-12-2024)“…Acynodon adriaticus, a small eusuchian from the Late Cretaceous of Italy, is known for its well‐preserved cranial and postcranial material. Despite its…”
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