Search Results - "HARLING, Otto K"

Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer by Barth, Rolf F, Vicente, M Graca H, Harling, Otto K, Kiger, 3rd, W S, Riley, Kent J, Binns, Peter J, Wagner, Franz M, Suzuki, Minoru, Aihara, Teruhito, Kato, Itsuro, Kawabata, Shinji

“…Boron neutron capture therapy (BNCT) is a biochemically targeted radiotherapy based on the nuclear capture and fission reactions that occur when…”
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Fission reactor based epithermal neutron irradiation facilities for routine clinical application in BNCT—Hatanaka memorial lecture by Harling, Otto K.

“…Based on experience gained in the recent clinical studies at MIT/Harvard, the desirable characteristics of epithermal neutron irradiation facilities for…”
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Functional and Histological Changes in Rat Lung after Boron Neutron Capture Therapy by Kiger, Jingli Liu, Kiger, W. S., Riley, Kent J., Binns, Peter J., Patel, Hemant, Hopewell, John W., Harling, Otto K., Busse, Paul M., Coderre, Jeffrey A.

“…Kiger, J. L., Kiger, W. S., III, Riley, K. J., Binns, P. J., Patel, H., Hopewell, J. W., Harling, O. K., Busse, P. M. and Coderre, J. A. Functional and…”
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Boron Neutron Capture Therapy: Cellular Targeting of High Linear Energy Transfer Radiation by Coderre, Jeffrey A., Turcotte, Julie C., Riley, Kent J., Binns, Peter J., Harling, Otto K., Kiger, W. S.

“…Boron neutron capture therapy (BNCT) is based on the preferential targeting of tumor cells with10 B and subsequent activation with thermal neutrons to produce…”
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Treatment planning and dosimetry for the Harvard-MIT Phase I clinical trial of cranial neutron capture therapy by Palmer, Matthew R, Goorley, J Timothy, Kiger, W S, Busse, Paul M, Riley, Kent J, Harling, Otto K, Zamenhof, Robert G

“…A Phase I trial of cranial neutron capture therapy (NCT) was conducted at Harvard-MIT. The trial was designed to determine maximum tolerated NCT radiation dose…”
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Irradiation performance of polytetrafluoroethylene (Teflon ®) in a mixed fast neutron and gamma radiation field by Harling, Otto K, Kohse, Gordon E, Riley, Kent J

“…Samples of polytetrafluoroethylene have been irradiated with a mixed field of fast neutrons and gamma rays using the MIT Research Reactor. Dose levels from…”
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A physical dosimetry intercomparison for BNCT by Riley, Kent J., Binns, Peter J., Greenberg, Dennis D., Harling, Otto K.

“…An intercomparison of physical dosimetry methods used at the Massachusetts Institute of Technology (MIT) and Brookhaven National Laboratory was completed to…”
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Fission reactor neutron sources for neutron capture therapy--a critical review by Harling, Otto K, Riley, Kent J

“…The status of fission reactor-based neutron beams for neutron capture therapy (NCT) is reviewed critically. Epithermal neutron beams, which are favored for…”
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A critical examination of the results from the Harvard-MIT NCT program phase I clinical trial of neutron capture therapy for intracranial disease by Busse, Paul M, Harling, Otto K, Palmer, Matthew R, Kiger, 3rd, W S, Kaplan, Jody, Kaplan, Irving, Chuang, Cynthia F, Goorley, J Tim, Riley, Kent J, Newton, Thomas H, Santa Cruz, Gustavo A, Lu, Xing-Qi, Zamenhof, Robert G

“…A phase I trial was designed to evaluate normal tissue tolerance to neutron capture therapy (NCT); tumor response was also followed as a secondary endpoint…”
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Improved dose targeting for a clinical epithermal neutron capture beam using optional (6)Li filtration by Binns, Peter J, Riley, Kent J, Ostrovsky, Yakov, Gao, Wei, Albritton, J Raymond, Kiger, 3rd, W S, Harling, Otto K

“…The aim of this study was to construct a (6)Li filter and to improve penetration of thermal neutrons produced by the fission converter-based epithermal neutron…”
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Improved Dose Targeting for a Clinical Epithermal Neutron Capture Beam Using Optional 6Li Filtration by Binns, Peter J., Riley, Kent J., Ostrovsky, Yakov, Gao, Wei, Albritton, J. Raymond, Kiger, W.S., Harling, Otto K.

“…Purpose: The aim of this study was to construct a 6Li filter and to improve penetration of thermal neutrons produced by the fission converter–based epithermal…”
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The MIT User Center for Neutron Capture Therapy Research by Harling, Otto K., Riley, Kent J., Binns, Peter J., Patel, Hemant, Coderre, Jeffrey A.

“…Harling, O. K., Riley, K. J., Binns, P. J., Patel, H. and Coderre, J. A. The MIT User Center for Neutron Capture Therapy Research. Radiat. Res. 164, 221–229…”
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Mixed field dosimetry of epithermal neutron beams for boron neutron capture therapy at the MITR-II research reactor by Rogus, R D, Harling, O K, Yanch, J C

“…During the past several years, there has been growing interest in Boron Neutron Capture Therapy (BNCT) using epithermal neutron beams. The dosimetry of these…”
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Microdosimetric intercomparison of BNCT beams at BNL and MIT by Burmeister, Jay, Riley, Kent, Coderre, Jeffrey A., Harling, Otto K., Ma, Ruimei, Wielopolski, Lucian, Kota, Chandrasekhar, Maughan, Richard L.

“…Microdosimetric measurements have been performed at the clinical beam intensities in two epithermal neutron beams, the Brookhaven Medical Research Reactor and…”
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An improved prompt gamma neutron activation analysis facility using a focused diffracted neutron beam by Riley, Kent J, Harling, Otto K

“…The performance of the prompt gamma neutron activation analysis (PGNAA) facility at the MIT Research Reactor has been improved by a series of modifications…”
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Fission reactor neutron sources for neutron capture therapy: a critical review: Boron neutron capture therapy: A critical assessment by HARLING, Otto K, RILEY, Kent J

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Improved Dose Targeting for a Clinical Epithermal Neutron Capture Beam Using Optional6 Li Filtration by Binns, Peter J., Ph.D, Riley, Kent J., Ph.D, Ostrovsky, Yakov, M.eng, Gao, Wei, M.S, Albritton, J. Raymond, M.S, Kiger, W.S., Ph.D, Harling, Otto K., Ph.D

“…Purpose: The aim of this study was to construct a6 Li filter and to improve penetration of thermal neutrons produced by the fission converter–based epithermal…”
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A critical examination of the results from the Harvard-MIT NCT program phase I clinical trial of neutron capture therapy for intracranial disease: Boron neutron capture therapy: A critical assessment by BUSSE, Paul M, HARLING, Otto K, SANTA CRUZ, Gustavo A, LU, Xing-Qi, ZAMENHOF, Robert G, PALMER, Matthew R, KIGER, W. S, KAPLAN, Jody, KAPLAN, Irving, CHUANG, Cynthia F, GOORLEY, J. Tim, RILEY, Kent J, NEWTON, Thomas H

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On-line beam monitoring for neutron capture therapy at the MIT Research Reactor by Harling, Otto K., Moulin, Damien J., Chabeuf, Jean-Michel, Solares, Guido R.

“…Neutron capture therapy sets new requirements on the measurement and monitoring of the radiation fields used in this new form of therapy. Beams used for…”
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Boron Neutron Capture Therapy: The Role of Peer Review by Harling, Otto K.

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