Search Results - "HARDY, Sharanda K"

D-Amino Acids Enhance the Activity of Antimicrobials against Biofilms of Clinical Wound Isolates of Staphylococcus aureus and Pseudomonas aeruginosa by SANCHEZ, Carlos J, AKERS, Kevin S, ROMANO, Desiree R, WOODBURY, Ronald L, HARDY, Sharanda K, MURRAY, Clinton K, WENKE, Joseph C

“…Within wounds, microorganisms predominantly exist as biofilms. Biofilms are associated with chronic infections and represent a tremendous clinical challenge…”
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Rifamycin Derivatives Are Effective Against Staphylococcal Biofilms In Vitro and Elutable From PMMA by Sanchez, Carlos J., Shiels, Stefanie M., Tennent, David J., Hardy, Sharanda K., Murray, Clinton K., Wenke, Joseph C.

“…Background Local antimicrobial delivery through polymethylmethacrylate beads (PMMA), commonly vancomycin, is used for the treatment of contaminated open…”
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Soluble factors from biofilms of wound pathogens modulate human bone marrow-derived stromal cell differentiation, migration, angiogenesis, and cytokine secretion by Ward, Catherine L, Sanchez, Jr, Carlos J, Pollot, Beth E, Romano, Desiree R, Hardy, Sharanda K, Becerra, Sandra C, Rathbone, Christopher R, Wenke, Joseph C

“…Chronic, non-healing wounds are often characterized by the persistence of bacteria within biofilms - aggregations of cells encased within a self-produced…”
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Staphylococcus aureus biofilms decrease osteoblast viability, inhibits osteogenic differentiation, and increases bone resorption in vitro by Sanchez, Jr, Carlos J, Ward, Catherine L, Romano, Desiree R, Hurtgen, Brady J, Hardy, Sharanda K, Woodbury, Ronald L, Trevino, Alex V, Rathbone, Christopher R, Wenke, Joseph C

“…Osteomyelitis is a severe and often debilitating disease characterized by inflammatory destruction of bone. Despite treatment, chronic infection often develops…”
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Human plasma enhances the expression of Staphylococcal microbial surface components recognizing adhesive matrix molecules promoting biofilm formation and increases antimicrobial tolerance In Vitro by Cardile, Anthony P, Sanchez, Jr, Carlos J, Samberg, Meghan E, Romano, Desiree R, Hardy, Sharanda K, Wenke, Joseph C, Murray, Clinton K, Akers, Kevin S

“…Microbial biofilms have been associated with the development of chronic human infections and represent a clinical challenge given their increased antimicrobial…”
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Dakin solution alters macrophage viability and function by Cardile, Anthony P., DO, Sanchez, Carlos J., PhD, Hardy, Sharanda K, Romano, Desiree R, Hurtgen, Brady J., PhD, Wenke, Joseph C., PhD, Murray, Clinton K., MD, Akers, Kevin S., MD

“…Abstract Background Macrophages are important in wound defense and healing. Dakin's solution (DS), buffered sodium hypochlorite, has been used since World War…”
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