Search Results - "HARADA, Takayuki"
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Neuroprotection, Growth Factors and BDNF-TrkB Signalling in Retinal Degeneration
Published in International journal of molecular sciences (20-09-2016)“…Neurotrophic factors play key roles in the development and survival of neurons. The potent neuroprotective effects of neurotrophic factors, including…”
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Changes in Vaccine Hesitancy in Japan across Five Months during the COVID-19 Pandemic and Its Related Factors
Published in Vaccines (Basel) (26-12-2021)“…Although vaccination is a particularly important countermeasure against the coronavirus disease 2019 (COVID-19), vaccine hesitancy may be a barrier to an…”
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3
Metallic delafossite thin films for unique device applications
Published in APL materials (01-07-2022)“…Metallic delafossites (ABO2) are layered oxides with quasi-two-dimensional conduction layers. Metallic delafossites are among the most conducting materials…”
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4
Monogenic gene therapy for glaucoma and optic nerve injury
Published in Neural regeneration research (01-03-2025)Get full text
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5
Asking one mechanism in glial cells during neuroinflammation
Published in Neural regeneration research (01-04-2025)Get full text
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Targeting Oxidative Stress for Treatment of Glaucoma and Optic Neuritis
Published in Oxidative medicine and cellular longevity (01-01-2017)“…Glaucoma is a neurodegenerative disease of the eye and it is one of the leading causes of blindness. Glaucoma is characterized by progressive degeneration of…”
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7
Rutile-type Ge x Sn1−x O2 alloy layers lattice-matched to TiO2 substrates for device applications
Published in Applied physics express (01-01-2024)“…We report the characterization and application of mist-CVD-grown rutile-structured Ge _x Sn _1− _x O _2 ( x = ∼ 0.53) films lattice-matched to isostructural…”
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8
Development and validation of Tagalog versions of the Drug Abuse Screening Test-20 (DAST-20) and Stimulant Relapse Risk Scale (SRRS) for drug users in the Philippines
Published in PloS one (01-01-2023)“…Methamphetamine use is becoming a major social issue in the Philippines, and this has been attracting international interest. Understanding the characteristics…”
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Nonreciprocal Transport in a Rashba Ferromagnet, Delafossite PdCoO2
Published in Nano letters (27-10-2021)“…Rashba interfaces yield efficient spin-charge interconversion and give rise to nonreciprocal transport phenomena. Here, we report magnetotransport experiments…”
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10
Survival of Alpha and Intrinsically Photosensitive Retinal Ganglion Cells in NMDA-Induced Neurotoxicity and a Mouse Model of Normal Tension Glaucoma
Published in Investigative ophthalmology & visual science (03-09-2019)“…We assess if α retinal ganglion cells (αRGCs) and intrinsically photosensitive retinal ganglion cells (ipRGCs) survive in mouse models of glaucoma. Two…”
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Differential effects of N-acetylcysteine on retinal degeneration in two mouse models of normal tension glaucoma
Published in Cell death & disease (28-01-2019)“…N -acetylcysteine (NAC) is widely used as a mucolytic agent and as an antidote to paracetamol overdose. NAC serves as a precursor of cysteine and stimulates…”
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12
Roles of the DOCK-D family proteins in a mouse model of neuroinflammation
Published in The Journal of biological chemistry (08-05-2020)“…The DOCK-D (dedicator of cytokinesis D) family proteins are atypical guanine nucleotide exchange factors that regulate Rho GTPase activity. The family consists…”
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Evaluation of the Intensive Treatment and Rehabilitation Program for Residential Treatment and Rehabilitation Centers (INTREPRET) in the Philippines: a study protocol for a randomized controlled trial
Published in Current controlled trials in cardiovascular medicine (11-12-2021)“…The Philippines has been severely affected by the methamphetamine crisis. The government has launched a policy war against drug use, although the severe…”
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14
Genetic inhibition of collapsin response mediator protein‐2 phosphorylation ameliorates retinal ganglion cell death in normal‐tension glaucoma models
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-08-2022)“…Glaucoma is a neurodegenerative disorder caused by the death of retinal ganglion cells (RGCs). Elevated intraocular pressure (IOP) is a cause of glaucoma…”
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Effects of constitutively active K-Ras on axon regeneration after optic nerve injury
Published in Neuroscience letters (16-03-2023)“…•The constitutively active form of K-Ras, K-RasV12, is known as a powerful oncogene.•K-RasV12 promoted retinal ganglion cell survival after optic nerve…”
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16
ASK1 signaling regulates phase-specific glial interactions during neuroinflammation
Published in Proceedings of the National Academy of Sciences - PNAS (08-02-2022)“…Neuroinflammation is well known to be associated with neurodegenerative diseases. Apoptosis signal-regulating kinase 1 (ASK1) is a mitogen-activated protein…”
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Valproic Acid Prevents NMDA-Induced Retinal Ganglion Cell Death via Stimulation of Neuronal TrkB Receptor Signaling
Published in The American journal of pathology (01-03-2015)“…Valproic acid (VPA) is widely prescribed for treatment of epilepsy, mood disorders, migraines, and neuropathic pain. It exerts its therapeutic benefits through…”
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Vision protection and robust axon regeneration in glaucoma models by membrane-associated Trk receptors
Published in Molecular therapy (01-03-2023)“…Activation of neurotrophic factor signaling is a promising therapy for neurodegeneration. However, the transient nature of ligand-dependent activation limits…”
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CCP1, a Regulator of Tubulin Post-Translational Modifications, Potentially Plays an Essential Role in Cerebellar Development
Published in International journal of molecular sciences (10-03-2023)“…The cytosolic carboxypeptidase (CCP) 1 protein, encoded by , is expressed in cerebellar Purkinje cells (PCs). The dysfunction of CCP1 protein (caused by point…”
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Changes in glial cells and neurotrophic factors due to rotenone-induced oxidative stress in Nrf2 knockout mice
Published in Experimental eye research (01-01-2023)“…Glaucoma is one of the most common causes of blindness worldwide. It is thought to be a multifactorial disease with underlying mechanisms that include…”
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