Search Results - "HAO, Chuan‐Ming"

Sirt1 Activation Ameliorates Renal Fibrosis by Inhibiting the TGF-β/Smad3 Pathway by Huang, Xin-Zhong, Wen, Donghai, Zhang, Min, Xie, Qionghong, Ma, Leting, Guan, Yi, Ren, Yueheng, Chen, Jing, Hao, Chuan-Ming

“…ABSTRACT TGF‐β signaling plays an important role in the pathogenesis and progression of chronic kidney disease (CKD). Smad3, a transcription factor, is a…”
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Nicotinamide Mononucleotide, an NAD + Precursor, Rescues Age-Associated Susceptibility to AKI in a Sirtuin 1-Dependent Manner by Guan, Yi, Wang, Su-Rong, Huang, Xin-Zhong, Xie, Qiong-Hong, Xu, Yun-Yu, Shang, Da, Hao, Chuan-Ming

“…The rapid growth of an aging population creates challenges regarding age-related diseases, including AKI, for which both the prevalence and death rate increase…”
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Recommendations by the Asian Pacific society of nephrology (APSN) on the appropriate use of HIF‐PH inhibitors by Yap, Desmond Y. H., McMahon, Lawrence P., Hao, Chuan‐Ming, Hu, Nan, Okada, Hirokazu, Suzuki, Yusuke, Kim, Sung Gyun, Lim, Soo Kun, Vareesangthip, Kriengsak, Hung, Chi‐Chih, Nangaku, Masaomi

“…Renal anaemia is a common and important complication in patients with chronic kidney disease (CKD). The current standard‐of‐care treatment for renal anaemia in…”
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Resveratrol attenuates diabetic nephropathy via modulating angiogenesis by Wen, Donghai, Huang, Xinzhong, Zhang, Min, Zhang, Liying, Chen, Jing, Gu, Yong, Hao, Chuan-Ming

“…Angiogenesis plays an important role in the pathogenesis of diabetic nephropathy (DN). In the present study, we investigated the therapeutic potential of…”
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Physiological regulation of prostaglandins in the kidney by Hao, Chuan-Ming, Breyer, Matthew D

“…Cyclooxygenase-derived prostanoids exert complex and diverse functions within the kidney. The biological effect of each prostanoid is controlled at multiple…”
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Mesangial cell‐derived tenascin‐C contributes to mesangial cell proliferation and matrix protein production in IgA nephropathy by Yan, Minhua, Liu, Shaojun, Zhang, Min, Lai, Lingyun, Xie, Qionghong, Hao, Chuan‐Ming

“…Aim Tenascin‐C (TNC), a non‐structural extracellular matrix glycoprotein, is transiently expressed during development or after injury, playing an important…”
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The hypoxia-inducible factor prolyl hydroxylase inhibitor FG4592 promotes natriuresis through upregulation of COX2 in the renal medulla by Guan, Nan, Zhang, Min, Gong, Wei-Yuan, Mao, Xiao-Yi, Yang, Si-Si, Hao, Chuan-Ming

“…The renal medulla is a key site for the regulation of renal sodium excretion. However, the molecular mechanism remains unclear. Cyclooxygenase 2 (COX2) is…”
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Sirt1 activation protects the mouse renal medulla from oxidative injury by He, Wenjuan, Wang, Yingying, Zhang, Ming-Zhi, You, Li, Davis, Linda S, Fan, Hong, Yang, Hai-Chun, Fogo, Agnes B, Zent, Roy, Harris, Raymond C, Breyer, Matthew D, Hao, Chuan-Ming

“…Sirtuin 1 (Sirt1) is a NAD+-dependent deacetylase that exerts many of the pleiotropic effects of oxidative metabolism. Due to local hypoxia and hypertonicity,…”
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The histone deacetylase, SIRT1, contributes to the resistance of young mice to ischemia/reperfusion-induced acute kidney injury by Fan, Hong, Yang, Hai-Chun, You, Li, Wang, Ying-Ying, He, Wen-Juan, Hao, Chuan-Ming

“…Acute kidney injury (AKI) is a critical condition with a mortality rate as high as 50% and significantly contributes to the burden of end-stage renal disease…”
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Renal Medullary Interstitial COX-2 (Cyclooxygenase-2) Is Essential in Preventing Salt-Sensitive Hypertension and Maintaining Renal Inner Medulla/Papilla Structural Integrity by Zhang, Ming-Zhi, Wang, Suwan, Wang, Yinqiu, Zhang, Yahua, Ming Hao, Chuan, Harris, Raymond C

“…COX (cyclooxygenase)-derived prostaglandins regulate renal hemodynamics and salt and water homeostasis. Inhibition of COX activity causes blood pressure…”
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Endothelial prostacyclin protects the kidney from ischemia-reperfusion injury by Cao, Yingxue, Guan, Yi, Xu, Yun-Yu, Hao, Chuan-Ming

“…Prostacyclin, or PGI 2 , is a product of PGI synthase (PGIS), down-stream of cyclooxygenase pathway. PGI 2 has been demonstrated to play an important role in…”
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Fibroblast-specific plasminogen activator inhibitor-1 depletion ameliorates renal interstitial fibrosis after unilateral ureteral obstruction by Yao, Lan, Wright, M Frances, Farmer, Brandon C, Peterson, Laura S, Khan, Amir M, Zhong, Jianyong, Gewin, Leslie, Hao, Chuan-Ming, Yang, Hai-Chun, Fogo, Agnes B

“…Plasminogen activator inhibitor-1 (PAI-1) expression increases extracellular matrix deposition and contributes to interstitial fibrosis in the kidney after…”
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Updates on Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors in the Treatment of Renal Anemia by Li, Jing, Haase, Volker H., Hao, Chuan-Ming

“…Background: Anemia is a common complication of chronic kidney disease. The hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) is a new class of…”
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ASIAN PACIFIC SOCIETY OF NEPHROLOGY CLINICAL PRACTICE GUIDELINE ON DIABETIC KIDNEY DISEASE by LIEW, Adrian, BAVANANDAN, Sunita, PRASAD, Narayan, WONG, Muh Geot, CHANG, Jer Ming, EIAM‐ONG, Somchai, HAO, Chuan‐Ming, LIM, Chiao Yuen, LIM, Soo Kun, OH, Kook‐Hwan, OKADA, Hirokazu, SUSANTITAPHONG, Paweena, LYDIA, Aida, TRAN, Huong Thi Bich, VILLANUEVA, Russell, YEO, See Cheng, TANG, Sydney C.W.

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Association between NAFLD and risk of prevalent chronic kidney disease: why there is a difference between east and west? by Zhang, Min, Lin, Su, Wang, Ming-Fang, Huang, Jiao-Feng, Liu, Shi-Ying, Wu, Su-Mei, Zhang, Hao-Yang, Wu, Zi-Mu, Liu, Wen-Yue, Zhang, Dong-Chu, Hao, Chuan-Ming, Zhu, Yue-Yong, Zheng, Ming-Hua, Wang, Xiao-Zhong

“…There is a discrepancy between west and east on the relationship between non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD). This study…”
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Matrix protein Tenascin-C promotes kidney fibrosis via STAT3 activation in response to tubular injury by Xie, Qionghong, Zhang, Min, Mao, Xiaoyi, Xu, Mingyue, Liu, Shaojun, Shang, Da, Xu, Yunyu, Chen, Ruiying, Guan, Yi, Huang, Xinzhong, Zent, Roy, Pozzi, Ambra, Hao, Chuan-Ming

“…Accumulating evidence indicates that the extracellular matrix (ECM) is not only a consequence of fibrosis, but also contributes to the progression of fibrosis,…”
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Case report: BTK inhibitors is effective in type II mixed cryoglobulinemia with wild-type MyD88 by Xu, Mingyue, Xu, Yunyu, Yuan, Li, Shang, Da, Chen, Ruiying, Liu, Shaojun, Li, Yan, Liu, Aiping, Liu, Ruilai, Wang, Qian, Ding, Tianling, Xie, Qionghong, Hao, Chuan-Ming

“…This study presents two cases of type II mixed cryoglobulinemia. One case is essential, while the other is presumably associated with hepatitis B virus (HBV)…”
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Rituximab as Initial Therapy in Adult Patients With Minimal Change Disease by Guan, Nan, Zhang, Min, Zhang, Min, Chen, Ruiying, Xie, Qionghong, Hao, Chuan-Ming

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Asian Pacific Society of Nephrology Clinical Practice Guideline on Diabetic Kidney Disease – An Executive Summary by Liew, Adrian, Bavanandan, Sunita, Prasad, Narayan, Wong, Muh Geot, Chang, Jer Ming, Eiam‐Ong, Somchai, Hao, Chuan‐Ming, Lim, Chiao Yuen, Lim, Soo Kun, OH, Kook‐Hwan, Okada, Hirokazu, Susantitaphong, Paweena, Lydia, Aida, Tran, Huong Thi Bich, Villanueva, Russell, Yeo, See Cheng, Tang, Sydney C.W.

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Mechanisms of Scarring in Focal Segmental Glomerulosclerosis by Sun, Ke, Xie, Qionghong, Hao, Chuan-Ming

“…Background: Focal segmental glomerulosclerosis (FSGS) is a histologic pattern characterized by focal glomerular scarring, which often progresses to systemic…”
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