Search Results - "HANSSON, Mattias"

Single-Cell Gene Expression Analysis of a Human ESC Model of Pancreatic Endocrine Development Reveals Different Paths to β-Cell Differentiation by Petersen, Maja Borup Kjær, Azad, Ajuna, Ingvorsen, Camilla, Hess, Katja, Hansson, Mattias, Grapin-Botton, Anne, Honoré, Christian

“…The production of insulin-producing β cells from human embryonic stem cells (hESCs) in vitro represents a promising strategy for a cell-based therapy for type…”
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Understanding human fetal pancreas development using subpopulation sorting, RNA sequencing and single-cell profiling by Ramond, Cyrille, Beydag-Tasöz, Belin Selcen, Azad, Ajuna, van de Bunt, Martijn, Petersen, Maja Borup Kjær, Beer, Nicola L, Glaser, Nicolas, Berthault, Claire, Gloyn, Anna L, Hansson, Mattias, McCarthy, Mark I, Honoré, Christian, Grapin-Botton, Anne, Scharfmann, Raphael

“…To decipher the populations of cells present in the human fetal pancreas and their lineage relationships, we developed strategies to isolate pancreatic…”
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Reconstructing human pancreatic differentiation by mapping specific cell populations during development by Ramond, Cyrille, Glaser, Nicolas, Berthault, Claire, Ameri, Jacqueline, Kirkegaard, Jeannette Schlichting, Hansson, Mattias, Honoré, Christian, Semb, Henrik, Scharfmann, Raphaël

“…Information remains scarce on human development compared to animal models. Here, we reconstructed human fetal pancreatic differentiation using cell surface…”
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Collagen Type I Improves the Differentiation of Human Embryonic Stem Cells towards Definitive Endoderm by Rasmussen, Camilla Holzmann, Petersen, Dorthe Roenn, Moeller, Jonas Bech, Hansson, Mattias, Dufva, Martin

“…Human embryonic stem cells have the ability to generate all cell types in the body and can potentially provide an unlimited source of cells for cell…”
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PCR-mediated deletion of plasmid DNA by Hansson, Mattias D., Rzeznicka, Kamila, Rosenbäck, Matilda, Hansson, Mats, Sirijovski, Nick

“…The PCR-mediated plasmid DNA deletion method is a simple approach to delete DNA sequences from plasmids using only one round of PCR, with two primers, and…”
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Controlling fluid flow to improve cell seeding uniformity by Reynolds, Paul M, Holzmann Rasmussen, Camilla, Hansson, Mattias, Dufva, Martin, Riehle, Mathis O, Gadegaard, Nikolaj

“…Standard methods for seeding monolayer cell cultures in a multiwell plate or dish do not uniformly distribute cells on the surface. With traditional methods,…”
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Retinoic Acid Synthesis Promotes Development of Neural Progenitors from Mouse Embryonic Stem Cells by Suppressing Endogenous, Wnt‐Dependent Nodal Signaling by Engberg, Nina, Kahn, Morten, Petersen, Dorthe Rønn, Hansson, Mattias, Serup, Palle

“…Embryonic stem (ES) cells differentiate spontaneously toward a neuroectodermal fate in serum‐free, adherent monocultures. Here, we show that this spontaneous…”
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Analysis of Differentiation Protocols Defines a Common Pancreatic Progenitor Molecular Signature and Guides Refinement of Endocrine Differentiation by Wesolowska-Andersen, Agata, Jensen, Rikke Rejnholdt, Alcántara, Marta Pérez, Beer, Nicola L., Duff, Claire, Nylander, Vibe, Gosden, Matthew, Witty, Lorna, Bowden, Rory, McCarthy, Mark I., Hansson, Mattias, Gloyn, Anna L., Honore, Christian

“…Several distinct differentiation protocols for deriving pancreatic progenitors (PPs) from human pluripotent stem cells have been described, but it remains to…”
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Porphyrin Binding and Distortion and Substrate Specificity in the Ferrochelatase Reaction: The Role of Active Site Residues by Karlberg, Tobias, Hansson, Mattias D., Yengo, Raymond K., Johansson, Renzo, Thorvaldsen, Hege O., Ferreira, Gloria C., Hansson, Mats, Al-Karadaghi, Salam

“…The specific insertion of a divalent metal ion into tetrapyrrole macrocycles is catalyzed by a group of enzymes called chelatases. Distortion of the…”
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Synergistic platelet inhibition between Omega-3 and acetylsalicylic acid dose titration; an observational study by Bagger, Harald, Hansson, Mattias, Kander, Thomas, Schött, Ulf

“…Omega-3 and acetylsalicylic acid (ASA) are two widely used "over-the-counter" drugs. Previous research has shown multiple electrode aggregometry (MEA) can…”
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Application-Oriented Bulk Cryopreservation of Human iPSCs in Cryo Bags Followed by Direct Inoculation in Scalable Suspension Bioreactors for Expansion and Neural Differentiation by Meiser, Ina, Alstrup, Monica, Khalesi, Elham, Stephan, Bianca, Speicher, Anna M, Majer, Julia, Kwok, Chee Keong, Neubauer, Julia C, Hansson, Mattias, Zimmermann, Heiko

“…Stem cell-based therapies are promising tools for regenerative medicine and require bulk numbers of high-quality cells. Currently, cells are produced on demand…”
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Amino Acid Residues His183 and Glu264 in Bacillus subtilis Ferrochelatase Direct and Facilitate the Insertion of Metal Ion into Protoporphyrin IX by Hansson, Mattias D, Karlberg, Tobias, Rahardja, Muhammad Arys, Al-Karadaghi, Salam, Hansson, Mats

“…Ferrochelatase catalyzes the terminal step in the heme biosynthetic pathway, i.e., the incorporation of Fe(II) into protoporphyrin IX. Various biochemical and…”
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Segmentation of B-mode cardiac ultrasound data by Bayesian Probability Maps by Hansson, Mattias, Brandt, Sami S., Lindström, Johan, Gudmundsson, Petri, Jujić, Amra, Malmgren, Andreas, Cheng, Yuanji

“…[Display omitted] •We want to determine the position of the endocardium in B-mode ultrasound sequences.•Bayesian Probability Maps give the probability of…”
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A late requirement for Wnt and FGF signaling during activin-induced formation of foregut endoderm from mouse embryonic stem cells by Hansson, Mattias, Olesen, Dorthe R., Peterslund, Janny M.L., Engberg, Nina, Kahn, Morten, Winzi, Maria, Klein, Tino, Maddox-Hyttel, Poul, Serup, Palle

“…Here we examine how BMP, Wnt, and FGF signaling modulate activin-induced mesendodermal differentiation of mouse ES cells grown under defined conditions in…”
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Artifactual Insulin Release From Differentiated Embryonic Stem Cells by HANSSON, Mattias, TONNING, Anna, MELTON, Douglas, SEMB, Henrik, SERUP, Palle, FRANDSEN, Ulrik, PETRI, Andreas, RAJAGOPAL, Jayaraj, ENGLUND, Mikael C. O, HELLER, R. Scott, HAKANSSON, Joakim, FLECKNER, Jan, SKÖLD, Helen Nilsson

“…Artifactual Insulin Release From Differentiated Embryonic Stem Cells Mattias Hansson 1 , Anna Tonning 2 , Ulrik Frandsen 1 , Andreas Petri 1 3 , Jayaraj…”
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NKX6.1 induced pluripotent stem cell reporter lines for isolation and analysis of functionally relevant neuronal and pancreas populations by Gupta, Shailesh Kumar, Wesolowska-Andersen, Agata, Ringgaard, Anna K., Jaiswal, Himjyot, Song, Luyan, Hastoy, Benoit, Ingvorsen, Camilla, Taheri-Ghahfarokhi, Amir, Magnusson, Björn, Maresca, Marcello, Jensen, Rikke R., Beer, Nicola L., Fels, Johannes J., Grunnet, Lars G., Thomas, Melissa K., Gloyn, Anna L., Hicks, Ryan, McCarthy, Mark I., Hansson, Mattias, Honoré, Christian

“…Recent studies have reported significant advances in the differentiation of human pluripotent stem cells to clinically relevant cell types such as the insulin…”
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Bacterial ferrochelatase turns human: Tyr13 determines the apparent metal specificity of Bacillus subtilis ferrochelatase by Hansson, Mattias D, Karlberg, Tobias, Söderberg, Christopher A. G, Rajan, Sreekanth, Warren, Martin J, Al-Karadaghi, Salam, Rigby, Stephen E. J, Hansson, Mats

“…Ferrochelatase catalyzes the insertion of Fe²⁺ into protoporphyrin IX. The enzymatic product heme (protoheme IX) is a well-known cofactor in a wide range of…”
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Metallation of the Transition-state Inhibitor N-methyl Mesoporphyrin by Ferrochelatase: Implications for the Catalytic Reaction Mechanism by Shipovskov, Stepan, Karlberg, Tobias, Fodje, Michel, Hansson, Mattias D., Ferreira, Gloria C., Hansson, Mats, Reimann, Curt T., Al-Karadaghi, Salam

“…Insertion of metals into various tetrapyrroles is catalysed by a group of enzymes called chelatases, e.g. nickel, cobalt, magnesium and ferro-chelatase. It has…”
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Crosstalk between metal ions in Bacillus subtilis ferrochelatase by Hansson, Mattias D, Lindstam, Mats, Hansson, Mats

“…Ferrochelatase (EC 4.99.1.1), the terminal enzyme in the heme biosynthetic pathway, catalyzes the insertion of Fe2+ into protoporphyrin IX, generating heme. In…”
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The suitability of Hester–Dendy macroinvertebrate samplers in fluctuating flows by Hansson, Mattias, Lind, Lovisa, Vernby, Andreas, Greenberg, Larry, Watz, Johan

“…Reliable methods for assessing the ecological status of degraded rivers are essential for evaluating restoration efforts in lotic habitats. Several methods are…”
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