Search Results - "HANSON, Richard W"

Resurgence of Serine: An Often Neglected but Indispensable Amino Acid by Kalhan, Satish C., Hanson, Richard W.

“…Serine is generally classified as a nutritionally nonessential (dispensable) amino acid, but metabolically, serine is indispensible and plays an essential role…”
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What Is the Metabolic Role of Phosphoenolpyruvate Carboxykinase? by Yang, Jianqi, Kalhan, Satish C., Hanson, Richard W.

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Plasma metabolomic profile in nonalcoholic fatty liver disease by Kalhan, Satish C, Guo, Lining, Edmison, John, Dasarathy, Srinivasan, McCullough, Arthur J, Hanson, Richard W, Milburn, Mike

“…Abstract The plasma profile of subjects with nonalcoholic fatty liver disease (NAFLD), steatosis, and steatohepatitis (NASH) was examined using an untargeted…”
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Glyceroneogenesis Is the Dominant Pathway for Triglyceride Glycerol Synthesis in Vivo in the Rat by Nye, Colleen K., Hanson, Richard W., Kalhan, Satish C.

“…Triglyceride synthesis in mammalian tissues requires glycerol 3-phosphate as the source of triglyceride glycerol. In this study the relative contribution of…”
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The dynamic metabolism of hyaluronan regulates the cytosolic concentration of UDP-GlcNAc by Hascall, Vincent C., Wang, Aimin, Tammi, Markku, Oikari, Sanna, Tammi, Raija, Passi, Alberto, Vigetti, Davide, Hanson, Richard W., Hart, Gerald W.

“…Hyaluronan, a macromolecular glycosaminoglycan, is normally synthesized by hyaluronan synthases at the plasma membrane using cytosolic UDP-GlcUA and UDP-GlcNAc…”
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The key role of anaplerosis and cataplerosis for citric acid cycle function by Owen, Oliver E, Kalhan, Satish C, Hanson, Richard W

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Analysis of the adult human plasma metabolome by Lawton, Kay A, Berger, Alvin, Mitchell, Matthew, Milgram, K Eric, Evans, Anne M, Guo, Lining, Hanson, Richard W, Kalhan, Satish C, Ryals, John A, Milburn, Michael V

“…It is well established that disease states are associated with biochemical changes (e.g., diabetes/glucose, cardiovascular disease/cholesterol), as are…”
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Aspects of the Control of Phosphoenolpyruvate Carboxykinase Gene Transcription by Yang, Jianqi, Reshef, Lea, Cassuto, Hanoch, Aleman, Gabriela, Hanson, Richard W.

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Regulation of Hepatic Gluconeogenesis by an ER-Bound Transcription Factor, CREBH by Lee, Min-Woo, Chanda, Dipanjan, Yang, Jianqi, Oh, Hyunhee, Kim, Su Sung, Yoon, Young-Sil, Hong, Sungpyo, Park, Keun-Gyu, Lee, In-Kyu, Choi, Cheol Soo, Hanson, Richard W., Choi, Hueng-Sik, Koo, Seung-Hoi

“…Endoplasmic reticulum (ER)-bound transcription factor families are shown to be involved in the control of various metabolic pathways. Here, we report a…”
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Enhanced Energy Metabolism Contributes to the Extended Life Span of Calorie-restricted Caenorhabditis elegans by Yuan, Yiyuan, Kadiyala, Chandra S., Ching, Tsui-Ting, Hakimi, Parvin, Saha, Sudipto, Xu, Hua, Yuan, Chao, Mullangi, Vennela, Wang, Liwen, Fivenson, Elayne, Hanson, Richard W., Ewing, Rob, Hsu, Ao-Lin, Miyagi, Masaru, Feng, Zhaoyang

“…Caloric restriction (CR) markedly extends life span and improves the health of a broad number of species. Energy metabolism fundamentally contributes to the…”
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Overexpression of the Cytosolic Form of Phosphoenolpyruvate Carboxykinase (GTP) in Skeletal Muscle Repatterns Energy Metabolism in the Mouse by Hakimi, Parvin, Yang, Jianqi, Casadesus, Gemma, Massillon, Duna, Tolentino-Silva, Fatima, Nye, Colleen K., Cabrera, Marco E., Hagen, David R., Utter, Christopher B., Baghdy, Yacoub, Johnson, David H., Wilson, David L., Kirwan, John P., Kalhan, Satish C., Hanson, Richard W.

“…Transgenic mice, containing a chimeric gene in which the cDNA for phosphoenolpyruvate carboxykinase (GTP) (PEPCK-C) (EC 4.1.1.32) was linked to the α-skeletal…”
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Metabolic and Genomic Response to Dietary Isocaloric Protein Restriction in the Rat by Kalhan, Satish C., Uppal, Sonal O., Moorman, Jillian L., Bennett, Carole, Gruca, Lourdes L., Parimi, Prabhu S., Dasarathy, Srinivasan, Serre, David, Hanson, Richard W.

“…We have examined hepatic, genomic, and metabolic responses to dietary protein restriction in the non-pregnant Sprague-Dawley rat. Animals were pair-fed either…”
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REGULATION OF PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP) GENE EXPRESSION by Hanson, Richard W, Reshef, Lea

“…Phosphoenolpyruvate carboxykinase (GTP) (EC 4.1.1.32) (PEPCK) is a key enzyme in the synthesis of glucose in the liver and kidney and of glyceride-glycerol in…”
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Ablation of Promyelocytic Leukemia Protein (PML) Re-patterns Energy Balance and Protects Mice from Obesity Induced by a Western Diet by Cheng, Xiwen, Guo, Shuang, Liu, Yu, Chu, Hao, Hakimi, Parvin, Berger, Nathan A., Hanson, Richard W., Kao, Hung-Ying

“…The promyelocytic leukemia protein is a well known tumor suppressor, but its role in metabolism is largely unknown. Mice with a deletion in the gene for PML…”
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Cited2, a Transcriptional Modulator Protein, Regulates Metabolism in Murine Embryonic Stem Cells by Li, Qiang, Hakimi, Parvin, Liu, Xia, Yu, Wen-Mei, Ye, Fang, Fujioka, Hisashi, Raza, Syed, Shankar, Eswar, Tang, Fangqiang, Dunwoodie, Sally L., Danielpour, David, Hoppel, Charles L., Ramírez-Bergeron, Diana L., Qu, Cheng-Kui, Hanson, Richard W., Yang, Yu-Chung

“…CREB-binding protein (CBP)/p300 interacting transactivator with glutamic acid (Glu) and aspartic acid (Asp)-tail 2 (Cited2) was recently shown to be essential…”
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Glycine and urea kinetics in nonalcoholic steatohepatitis in human: effect of intralipid infusion by Dasarathy, Srinivasan, Kasumov, Takhar, Edmison, John M, Gruca, Lourdes L, Bennett, Carole, Duenas, Clarita, Marczewski, Susan, McCullough, Arthur J, Hanson, Richard W, Kalhan, Satish C

“…The rates of oxidation of glycine and ureagenesis were quantified in the basal state and in response to an intravenous infusion of intralipid with heparin (IL)…”
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Glucocorticoids Regulate Transcription of the Gene for Phosphoenolpyruvate Carboxykinase in the Liver via an Extended Glucocorticoid Regulatory Unit by Cassuto, Hanoch, Kochan, Karen, Chakravarty, Kaushik, Cohen, Hannah, Blum, Barak, Olswang, Yael, Hakimi, Parvin, Xu, Chuan, Massillon, Duna, Hanson, Richard W., Reshef, Lea

“…The hepatic transcriptional regulation by glucocorticoids of the cytosolic form of phosphoenolpyruvate carboxykinase (PEPCK-C) gene is coordinated by…”
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A computer model of gluconeogenesis and lipid metabolism in the perfused liver by Chalhoub, Elie, Hanson, Richard W, Belovich, Joanne M

“…A mathematical model of the perfused rat liver was developed to predict intermediate metabolite concentrations and fluxes in response to changes in various…”
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Nanoparticles of Compacted DNA Transfect Postmitotic Cells by Liu, Ge, Li, DeShan, Pasumarthy, Murali K., Kowalczyk, Tomasz H., Gedeon, Christopher R., Hyatt, Susannah L., Payne, Jennifer M., Miller, Timothy J., Brunovskis, Peter, Fink, Tamara L., Muhammad, Osman, Moen, Robert C., Hanson, Richard W., Cooper, Mark J.

“…Charge-neutral DNA nanoparticles have been developed in which single molecules of DNA are compacted to their minimal possible size. We speculated that the…”
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Phosphoenolpyruvate carboxykinase and the critical role of cataplerosis in the control of hepatic metabolism by Hakimi, Parvin, Johnson, Mark T, Yang, Jianqi, Lepage, David F, Conlon, Ronald A, Kalhan, Satish C, Reshef, Lea, Tilghman, Shirley M, Hanson, Richard W

“…The metabolic function of PEPCK-C is not fully understood; deletion of the gene for the enzyme in mice provides an opportunity to fully assess its function…”
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