Search Results - "HANSEN, Troels Krarup"

MASP‐2 deficiency does not prevent the progression of diabetic kidney disease in a mouse model of type 1 diabetes by Charlotte Brinck, Holt, Lene, Halkjær, Tom, Dudler, Wilhelm, Schwaeble, Troels Krarup, Hansen, Steffen, Thiel, Jakob Appel, Østergaard

“…Mannan‐binding lectin (MBL) initiates the lectin pathway of complement and has been linked to albuminuria and mortality in diabetes. We hypothesize that…”
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FGF21 and glycemic control in patients with T1D by Rosell Rask, Simone, Krarup Hansen, Troels, Bjerre, Mette

“…Purpose Fibroblast growth factor (FGF) 21 is a circulating hormone with an important role in metabolic regulation. FGF21 production in humans responds…”
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Tight Glycemic Control Protects the Myocardium and Reduces Inflammation in Neonatal Heart Surgery by Vlasselaers, Dirk, MD, PhD, Mesotten, Dieter, MD, PhD, Langouche, Lies, PhD, Vanhorebeek, Ilse, PhD, van den Heuvel, Ingeborg, MD, Milants, Ilse, RN, Wouters, Pieter, MS, Wouters, Patrick, MD, PhD, Meyns, Bart, MD, PhD, Bjerre, Mette, PhD, Hansen, Troels Krarup, MD, PhD, Van den Berghe, Greet, MD, PhD

“…Background Neonatal cardiac surgery evokes hyperglycemia and a systemic inflammatory response. Hyperglycemia is associated with intensified inflammation and…”
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ChatGPT- versus human-generated answers to frequently asked questions about diabetes: A Turing test-inspired survey among employees of a Danish diabetes center by Hulman, Adam, Dollerup, Ole Lindgård, Mortensen, Jesper Friis, Fenech, Matthew E, Norman, Kasper, Støvring, Henrik, Hansen, Troels Krarup

“…Large language models have received enormous attention recently with some studies demonstrating their potential clinical value, despite not being trained…”
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Randomized controlled study to evaluate the impact of flexible patient‐controlled visits in people with type 1 diabetes: The DiabetesFlex Trial by Laurberg, Tinne, Schougaard, Liv Marit Valen, Hjollund, Niels Henrik Ingvar, Lomborg, Kirsten Elisabeth, Hansen, Troels Krarup, Jensen, Annesofie Lunde

“…Aim The objective of this study was to assess the impact of health care–initiated visits versus patient‐controlled flexible visits on clinical and…”
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Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit by HENCKAERTS, Liesbet, NIELSEN, Kaspar R, VERMEIRE, Séverine, RUTGEERTS, Paul, THIEL, Steffen, WILMER, Alexander, KRARUP HANSEN, Troels, VAN DEN BERGHE, Greet, STEFFENSEN, Rudi, VAN STEEN, Kristel, MATHIEU, Chantal, GIULIETTI, Annapaula, WOUTERS, Pieter J, MILANTS, Ilse, VANHOREBEEK, Ilse, LANGOUCHE, Lies

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Switching to Degludec from Other Basal Insulins is Associated with Reduced Hypoglycemia Rates: a Prospective Study by Fadini, Gian Paolo, Feher, Michael, Hansen, Troels Krarup, de Valk, Harold W, Koefoed, Mette Marie, Wolden, Michael, Zimmermann, Esther, Jendle, Johan

“…Observational studies of insulin degludec (degludec) with hypoglycemia events prospectively recorded are lacking. To evaluate the safety and effectiveness of…”
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Flexible patient‐reported outcome‐based telehealth follow‐up for type 1 diabetes: A qualitative study by Jensen, Annesofie L., Schougaard, Liv Marit Valen, Laurberg, Tinne, Hansen, Troels Krarup, Lomborg, Kirsten

“…Background Successful diabetes management requires collaboration between patients and healthcare professionals and should be aligned with an individual's…”
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Effects of DPP‐4 inhibitors, GLP‐1 receptor agonists, SGLT‐2 inhibitors and sulphonylureas on mortality, cardiovascular and renal outcomes in type 2 diabetes: A network meta‐analyses‐driven approach by Brønden, Andreas, Christensen, Mikkel Bring, Glintborg, Dorte, Snorgaard, Ole, Kofoed‐Enevoldsen, Allan, Madsen, Gitte Krogh, Toft, Katja, Kristensen, Jette Kolding, Højlund, Kurt, Hansen, Troels Krarup, Søndergaard, Esben, Hansen, Katrine Bagge

“…Aims The aim of our meta‐analyses was to compare the effects of glucose‐lowering drugs on mortality, cardiovascular and renal endpoints for a range of type 2…”
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Hypoglycemia event prediction from CGM using ensemble learning by Fleischer, Jesper, Hansen, Troels Krarup, Cichosz, Simon Lebech

“…This work sought to explore the potential of using standalone continuous glucose monitor (CGM) data for the prediction of hypoglycemia utilizing a large cohort…”
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Safety and convenience of once-weekly somapacitan in adult GH deficiency: a 26-week randomized, controlled trial by Johannsson, Gudmundur, Feldt-Rasmussen, Ulla, Håkonsson, Ida Holme, Biering, Henrik, Rodien, Patrice, Tahara, Shigeyuki, Toogood, Andrew, Rasmussen, Michael Højby

“…Objective Somapacitan is a reversible albumin-binding growth hormone (GH) derivative, developed for once-weekly administration. This study aimed to evaluate…”
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Effect of insulin degludec versus insulin glargine U100 on nocturnal glycaemia assessed by plasma glucose profiles in people with type 1 diabetes prone to nocturnal severe hypoglycaemia by Brøsen, Julie Maria Bøggild, Agesen, Rikke Mette, Kristensen, Peter Lommer, Alibegovic, Amra Ciric, Andersen, Henrik Ullits, Beck‐Nielsen, Henning, Gustenhoff, Peter, Hansen, Troels Krarup, Hedetoft, Christoffer, Jensen, Tonny, Stolberg, Charlotte Røn, Juhl, Claus Bogh, Lerche, Susanne Søgaard, Nørgaard, Kirsten, Parving, Hans‐Henrik, Tarnow, Lise, Thorsteinsson, Birger, Pedersen‐Bjergaard, Ulrik

“…Aim To compare nocturnal glucose profiles according to hourly plasma glucose measurements during treatment with insulin degludec and insulin glargine U100 in a…”
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Ghrelin Infusion in Humans Induces Acute Insulin Resistance and Lipolysis Independent of Growth Hormone Signaling by VESTERGAARD, Esben Thyssen, GORMSEN, Lars Christian, JESSEN, Niels, LUND, Sten, HANSEN, Troels Krarup, MOLLER, Niels, JORGENSEN, Jens Otto Lunde

“…Ghrelin Infusion in Humans Induces Acute Insulin Resistance and Lipolysis Independent of Growth Hormone Signaling Esben Thyssen Vestergaard , Lars Christian…”
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Glycemic variability is associated with reduced cardiac autonomic modulation in women with type 2 diabetes by Fleischer, Jesper, Lebech Cichosz, Simon, Hoeyem, Pernille, Laugesen, Esben, Loegstrup Poulsen, Per, Sandahl Christiansen, Jens, Tarnow, Lise, Hansen, Troels Kraup

“…To investigate the sex differences in cardiac autonomic modulation in patients with newly diagnosed type 2 diabetes and to determine whether cardiac autonomic…”
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Intensive Insulin Therapy Exerts Antiinflammatory Effects in Critically Ill Patients and Counteracts the Adverse Effect of Low Mannose-Binding Lectin Levels by Hansen, Troels Krarup, Thiel, Steffen, Wouters, Pieter Jozef, Christiansen, Jens Sandahl, Van den Berghe, Greet

“…Adverse outcome of critical illness is often caused by systemic inflammation and sepsis. A recent study showed that mortality is significantly reduced by…”
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Mannose-binding lectin and risk of infections in type 2 diabetes: A Danish cohort study by Gedebjerg, Anne, Thomsen, Reimar Wernich, Kjaergaard, Alisa Devedzic, Steffensen, Rudi, Nielsen, Jens Steen, Rungby, Jørgen, Friborg, Søren Gunnar, Brandslund, Ivan, Thiel, Steffen, Beck-Nielsen, Henning, Sørensen, Henrik Toft, Hansen, Troels Krarup, Bjerre, Mette

“…In individuals at increased risk of infections, e.g., patients with type 2 diabetes, low MBL may have detrimental effects. We used the Mendelian randomization…”
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The pattern-recognition molecule H-ficolin in relation to diabetic kidney disease, mortality, and cardiovascular events in type 1 diabetes by Østergaard, Jakob Appel, Jansson Sigfrids, Fanny, Forsblom, Carol, Dahlström, Emma H., Thorn, Lena M., Harjutsalo, Valma, Flyvbjerg, Allan, Thiel, Steffen, Hansen, Troels Krarup, Groop, Per-Henrik

“…H-ficolin recognizes patterns on microorganisms and stressed cells and can activate the lectin pathway of the complement system. We aimed to assess H-ficolin…”
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Diabetes Is Associated with Increased Autoreactivity of Mannan-Binding Lectin by Hansen, Troels Krarup, Thiel, Steffen, Østergaard, Jakob Appel, Axelgaard, Esben

“…Mannan-binding lectin (MBL) has been reported to be involved in the pathophysiology of diabetic nephropathy. MBL is a pattern-recognition molecule of the…”
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Complement Receptor 2 Based Immunoassay Measuring Activation of the Complement System at C3-Level in Plasma Samples From Mice and Humans by Halkjær, Lene, Troldborg, Anne, Pedersen, Henrik, Jensen, Lisbeth, Hansen, Annette Gudmann, Hansen, Troels Krarup, Bjerre, Mette, Østergaard, Jakob Appel, Thiel, Steffen

“…We aimed at establishing a sensitive and robust assay for estimation of systemic complement activation at complement component C3 level in mouse and human…”
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Continuous glucose monitoring adds information beyond HbA1c in well-controlled diabetes patients with early cardiovascular autonomic neuropathy by Fleischer, Jesper, Laugesen, Esben, Cichosz, Simon Lebech, Hoeyem, Pernille, Dejgaard, Thomas Fremming, Poulsen, Per Loegstrup, Tarnow, Lise, Hansen, Troels Krarup

“…Hyperglycemia as evaluated by HbA1c is a risk factor for the development of cardiovascular autonomic neuropathy (CAN). The aim of the present study was to…”
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