Search Results - "HANSEN, Nils"

Screening of DNA-Encoded Small Molecule Libraries inside a Living Cell by Petersen, Lars K, Christensen, Allan B, Andersen, Jacob, Folkesson, Charlotta G, Kristensen, Ole, Andersen, Charlotte, Alzu, Amaya, Sløk, Frank A, Blakskjær, Peter, Madsen, Daniel, Azevedo, Carlos, Micco, Iolanda, Hansen, Nils J. V

“…DNA-encoded small molecule libraries (DELs) have facilitated the discovery of novel modulators of many different therapeutic protein targets. We report the…”
Get full text

The holist tradition in twentieth century genetics. Wilhelm Johannsen's genotype concept by Roll‐Hansen, Nils

“…The terms ‘genotype’, ‘phenotype’ and ‘gene’ originally had a different meaning from that in the Modern Synthesis. These terms were coined in the first decade…”
Get full text

Providing effective constraints for developing ketene combustion mechanisms: A detailed kinetic investigation of diacetyl flames by Sun, Wenyu, Wang, Jiaxing, Huang, Can, Hansen, Nils, Yang, Bin

“…Ketene is an important combustion intermediate, but due to its high reactivity, it has been difficult to validate the corresponding kinetic sub-mechanisms with…”
Get full text

Mass Spectrometric Lipid Profiles of Picosecond Infrared Laser‐Generated Tissue Aerosols Discriminate Different Brain Tissues by Wurlitzer, Marcus, Hessling, Elisabeth, Rinas, Karsten, Fuh, MarcelineManka, Petersen, Hannes, Ricklefs, Franz, Lamszus, Katrin, Regelsberger, Jan, Maier, Stephanie, Kruber, Sebastian, Hansen, Nils‐Owe, Miller, RJDwayne, Schlüter, Hartmut

“…Background and Objectives A picosecond infrared laser (PIRL) has recently been demonstrated to cut biological tissue without scar formation based on the…”
Get full text

Unraveling the structure and chemical mechanisms of highly oxygenated intermediates in oxidation of organic compounds by Wang, Zhandong, Popolan-Vaida, Denisia M., Chen, Bingjie, Moshammer, Kai, Mohamed, Samah Y., Wang, Heng, Sioud, Salim, Raji, Misjudeen A., Kohse-Höinghaus, Katharina, Hansen, Nils, Dagaut, Philippe, Leone, Stephen R., Sarathy, S. Mani

“…Decades of research on the autooxidation of organic compounds have provided fundamental and practical insights into these processes; however, the structure of…”
Get full text

Biofuel Combustion Chemistry: From Ethanol to Biodiesel by Kohse-Höinghaus, Katharina, Oßwald, Patrick, Cool, Terrill A, Kasper, Tina, Hansen, Nils, Qi, Fei, Westbrook, Charles K, Westmoreland, Phillip R

“…Biofuels, such as bio-ethanol, bio-butanol, and biodiesel, are of increasing interest as alternatives to petroleum-based transportation fuels because they…”
Get full text

Quantification of the Keto-Hydroperoxide (HOOCH2OCHO) and Other Elusive Intermediates during Low-Temperature Oxidation of Dimethyl Ether by Moshammer, Kai, Jasper, Ahren W, Popolan-Vaida, Denisia M, Wang, Zhandong, Bhavani Shankar, Vijai Shankar, Ruwe, Lena, Taatjes, Craig A, Dagaut, Philippe, Hansen, Nils

“…This work provides new temperature-dependent mole fractions of elusive intermediates relevant to the low-temperature oxidation of dimethyl ether (DME). It…”
Get full text

Inhibition of interleukin-1β reduces myelofibrosis and osteosclerosis in mice with JAK2-V617F driven myeloproliferative neoplasm by Rai, Shivam, Grockowiak, Elodie, Hansen, Nils, Luque Paz, Damien, Stoll, Cedric B., Hao-Shen, Hui, Mild-Schneider, Gabriele, Dirnhofer, Stefan, Farady, Christopher J., Méndez-Ferrer, Simón, Skoda, Radek C.

“…Interleukin-1β (IL-1β) is a master regulator of inflammation. Increased activity of IL-1β has been implicated in various pathological conditions including…”
Get full text

An experimental and kinetic modeling study on dimethyl carbonate (DMC) pyrolysis and combustion by Sun, Wenyu, Yang, Bin, Hansen, Nils, Westbrook, Charles K., Zhang, Feng, Wang, Gao, Moshammer, Kai, Law, Chung K.

“…Dimethyl carbonate (DMC) is a promising oxygenated additive or substitute for hydrocarbon fuels, because of the absence of C–C bonds and the large oxygen…”
Get full text

IL1RAP antibodies block IL-1–induced expansion of candidate CML stem cells and mediate cell killing in xenograft models by Ågerstam, Helena, Hansen, Nils, von Palffy, Sofia, Sandén, Carl, Reckzeh, Kristian, Karlsson, Christine, Lilljebjörn, Henrik, Landberg, Niklas, Askmyr, Maria, Högberg, Carl, Rissler, Marianne, Porkka, Kimmo, Wadenvik, Hans, Mustjoki, Satu, Richter, Johan, Järås, Marcus, Fioretos, Thoas

“…Chronic myeloid leukemia (CML) is currently treated with tyrosine kinase inhibitors, but these do not effectively eliminate the CML stem cells. As a…”
Get full text

Detection and Identification of the Keto-Hydroperoxide (HOOCH2OCHO) and Other Intermediates during Low-Temperature Oxidation of Dimethyl Ether by Moshammer, Kai, Jasper, Ahren W, Popolan-Vaida, Denisia M, Lucassen, Arnas, Diévart, Pascal, Selim, Hatem, Eskola, Arkke J, Taatjes, Craig A, Leone, Stephen R, Sarathy, S. Mani, Ju, Yiguang, Dagaut, Philippe, Kohse-Höinghaus, Katharina, Hansen, Nils

“…In this paper we report the detection and identification of the keto-hydroperoxide (hydroperoxymethyl formate, HPMF, HOOCH2OCHO) and other partially oxidized…”
Get full text

A further experimental and modeling study of acetaldehyde combustion kinetics by Tao, Tao, Kang, Shiqing, Sun, Wenyu, Wang, Jiaxing, Liao, Handong, Moshammer, Kai, Hansen, Nils, Law, Chung K., Yang, Bin

“…Acetaldehyde is an important intermediate and a toxic emission in the combustion of fuels, especially for biofuels. To better understand its combustion…”
Get full text

Wear Behavior of Metal Bonded Grinding Tools When Grinding Ti-6Al-4V in an Oxygen-Free Atmosphere by Denkena, Berend, Bergmann, Benjamin, Hansen, Nils, Heller, Christian

“…In the current study, the wear behavior of bronze-bonded grinding tools when grinding the titanium alloy Ti-6Al-4V was explored. In this process, oxidation…”
Get full text

Additional chain-branching pathways in the low-temperature oxidation of branched alkanes by Wang, Zhandong, Zhang, Lidong, Moshammer, Kai, Popolan-Vaida, Denisia M., Shankar, Vijai Shankar Bhavani, Lucassen, Arnas, Hemken, Christian, Taatjes, Craig A., Leone, Stephen R., Kohse-Höinghaus, Katharina, Hansen, Nils, Dagaut, Philippe, Sarathy, S. Mani

“…Chain-branching reactions represent a general motif in chemistry, encountered in atmospheric chemistry, combustion, polymerization, and photochemistry; the…”
Get full text

Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia by Ågerstam, Helena, Karlsson, Christine, Hansen, Nils, Sandén, Carl, Askmyr, Maria, von Palffy, Sofia, Högberg, Carl, Rissler, Marianne, Wunderlich, Mark, Juliusson, Gunnar, Richter, Johan, Sjöström, Kjell, Bhatia, Ravi, Mulloy, James C., Järås, Marcus, Fioretos, Thoas

“…Acute myeloid leukemia (AML) is associated with a poor survival rate, and there is an urgent need for novel and more efficient therapies, ideally targeting AML…”
Get full text

Influence of an Oxygen-Free Atmosphere on Process Forces and Workpiece Quality during the Surface Grinding of Ti-6Al-4V by Denkena, Berend, Bergmann, Benjamin, Hansen, Nils, Lang, Roman

“…Most manufacturing processes, such as grinding, are usually conducted in a standard air atmosphere. The oxygen within this atmosphere leads to oxidation…”
Get full text

Exploring the high-temperature kinetics of diethyl carbonate (DEC) under pyrolysis and flame conditions by Sun, Wenyu, Huang, Can, Tao, Tao, Zhang, Feng, Li, Wei, Hansen, Nils, Yang, Bin

“…To pursue insights into the high-temperature kinetics of diethyl carbonate (DEC), a potential clean oxygenated additive for diesel fuels, a systematical…”
Get full text

Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein by Järås, Marcus, Johnels, Petra, Hansen, Nils, Ågerstam, Helena, Tsapogas, Panagiotis, Rissler, Marianne, Lassen, Carin, Olofsson, Tor, Bjerrum, Ole Weis, Richter, Johan, Fioretos, Thoas

“…Chronic myeloid leukemia (CML) is genetically characterized by the Philadelphia (Ph) chromosome, formed through a reciprocal translocation between chromosomes…”
Get full text

Comparative study of wound healing in rat skin following incision with a novel picosecond infrared laser (PIRL) and different surgical modalities by Petersen, Hannes, Tavakoli, Fatemeh, Kruber, Sebastian, Münscher, Adrian, Gliese, Alexandra, Hansen, Nils-Owe, Uschold, Stephanie, Eggert, Dennis, Robertson, Wesley D., Gosau, Tobias, Sehner, Susanne, Kwiatkowski, Marcel, Schlüter, Hartmut, Schumacher, Udo, Knecht, Rainald, Miller, R.J. Dwayne

“…Background and Objective As a result of wound healing the original tissue is replaced by dysfunctional scar tissue. Reduced tissue damage during surgical…”
Get full text

Sampling of Tissues with Laser Ablation for Proteomics: Comparison of Picosecond Infrared Laser and Microsecond Infrared Laser by Krutilin, Andrey, Maier, Stephanie, Schuster, Raphael, Kruber, Sebastian, Kwiatkowski, Marcel, Robertson, Wesley D, Hansen, Nils-Owe, Miller, R. J. Dwayne, Schlüter, Hartmut

“…It was recently shown that sampling of tissues with a picosecond infrared laser (PIRL) for analysis with bottom-up proteomics is advantageous compared to…”
Get full text