Search Results - "HANOCQ, M"

Photodynamic DNA damage mediated by δ-aminolevulinic acid-induced porphyrins by Duez, P., Hanocq, M., Dubois, J.

“…The mutagenic properties of UVA are thought to be predominantly radical-mediated, which supposes endogenous sensitizers. In order to investigate a possible…”
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Ethyl acetate extraction procedure and isocratic high-performance liquid chromatographic assay for testosterone metabolites in cell microsomes by Baltes, M.R.H, Dubois, J.G, Hanocq, M

“…An isocratic reversed-phase high-performance liquid chromatography (HPLC) method was developed and validated for separation of testosterone and its main…”
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Application to drug–food interactions of living cells as in vitro model expressing cytochrome P450 activity: enzyme inhibition by lemon juice by Baltes, M.R.H, Dubois, J.G, Hanocq, M

“…Classical inhibitors of human cytochrome P450 3A4 activity, such as ketoconazol and quercetin, are tested to prove the efficiency of a new metabolisation model…”
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Chromatographic determination of 8-oxo-7,8-dihydro-2'-deoxyguanosine in cellular DNA: a validation study by Duez, P, Helson, M, Some, T I, Dubois, J, Hanocq, M

“…Although a series of biomarkers are widely used for the estimation of oxidative damage to biomolecules, validations of the analytical methods have seldom been…”
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Synthesis and cytotoxicity studies of new analogues of polyamines by Badolo, L, Gelbcke, M, Dubois, J, Hanocq, M

“…In order to regulate simultaneously the biosynthesis and the transport of natural polyamines, the synthesis of a series of N-methylated analogues of…”
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Ability of bisbenzylputrescine and propanediamine analogs to modulate the intracellular polyamine pool of P388D1 cells by BADOLO, L, HANOCQ, M, DUBOIS, J

“…The effects of a series of bisbenzyldiamine analogs have been tested on P388D1 cell line in vitro. Their effects on cell growth, polyamine oxidase (PAO)…”
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HPLC determination of a new multidrug resistance modulator (S9788) extracted from cancer cells in vitro by Tassin, J.P., Dubois, J., Hanocq, M., Atassi, G.

“…S9788 is a novel triazinodiaminopiperidine derivative which reverses the multidrug resistance of tumour cells to anticancer drugs. In this study, a new HPLC…”
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Chlordiazepoxide photoisomerization kinetics into oxaziridine. A HPLC study by Soentjens-Werts, V., Dubois, J.G., Atassi, G., Hanocq, M.

“…It was proved that the N 4-oxide group included in chlordiazepoxide (CDZ) is involved in its phototoxicity. At a wavelength of 350 nm, CDZ photoisomerizes only…”
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Comparison of two cytotoxicity assays--tetrazolium derivative reduction (MTT) and tritiated thymidine uptake--on three malignant mouse cell lines using chemotherapeutic agents and investigational drugs by Arnould, R, Dubois, J, Abikhalil, F, Libert, A, Ghanem, G, Atassi, G, Hanocq, M, Lejeune, F J

“…Two different techniques [reduction of a tetrazolium derivative (MTT) and 3HTdR uptake assays] were compared in order to evaluate the cytotoxic effects of…”
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Simultaneous determination of the ionisation and dimerization constants and the partition and ion pair extraction coefficients for 1–8 naphtyridine derivatives by Abi Khalil, F., Van Damme, M., Hanocq, M., Mauriac, P., Saint-Germain, J., Bouzard, D., Dauphin, J.F.

“…Conventional experimental studies of water/octanol partition at different pHs and concentrations were used to simultaneously evaluate (i) the true P…”
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Cytotoxicity of polyamines to Amoeba proteus : Role of polyamine oxidase by SCHENKEL, E, DUBOIS, J. G, HELSON-CAMBIER, M, HANOCQ, M

“…It has been shown that oxidation of polyamines by polyamine oxidases can produce toxic compounds (H2O2, aldehydes, ammonia) and that the polyamine…”
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Use of an Amoeba proteus model for in vitro cytotoxicity testing in phytochemical research. Application to Euphorbia hirta extracts by Duez, P, Livaditis, A, Guissou, P I, Sawadogo, M, Hanocq, M

“…Amoeba proteus is proposed as a low-cost multi-purpose biochemical tool for screening and standardizing cytotoxic plant extracts with possible application in…”
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A new method to estimate parameters of pharmacokinetics with enterohepatic circulation by ABI KHALIL, F, HANOCQ, M, DUBOIS, J

“…A new method of estimating pharmacokinetic parameters for enterohepatic recirculation models is presented. The algorithm, based on the simplex method, assures…”
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Tumor pharmacokinetics of hexamethylmelamine in CDF1 mice bearing P388 leukemia by Dubois, J, Atassi, G, Hanocq, M, Abikhalil, F

“…The pharmacokinetics and metabolism of hexamethylmelamine (HMM) have been studied in CDF1, mice bearing P388 leukemia. The results obtained for this tumor,…”
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Pharmacokinetics and metabolism of hexamethylmelamine in mice bearing renal cell tumors by DUBOIS, J, ATASSI, G, HANOCQ, M, ABIKHALIL, F

“…The pharmacokinetics of hexamethylmelamine (HMM) and its main metabolites hydroxymethylpentamethylmelamine (HMPMM), pentamethylmelamine (PMM), and 2,2,4,6,…”
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Plasma and erythrocyte zinc, copper and selenium in cystic fibrosis by Neve, J, Van Geffel, R, Hanocq, M, Molle, L

“…Plasma and erythrocyte zinc, copper and selenium were measured in 20 cystic fibrosis children, aged 7 to 19 years. Mean plasma zinc and copper levels were not…”
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Pharmacokinetics and metabolism of hexamethylmelamine in mice after IP administration by DUBOIS, J, ATASSI, G, HANOCQ, M, ABIKHALIL, F

“…The pharmacokinetics of hexamethylmelamine (HMM) and its first metabolite (hydroxymethylpentamethylmelamine: HMPMM) following IP bolus dose of 200 mg/kg were…”
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Improved high-performance liquid chromatographic method for the determination of polyamines as their benzoylated derivatives: application to P388 cancer cells by Schenkel, E., Berlaimont, V., Dubois, J., Helson-Cambier, M., Hanocq, M.

“…A simple reversed-phase HPLC method was developed for the determination of eight polyamines or monoacetylpolyamines, as their benzoylated derivatives…”
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In vitro cytotoxicity of hexamethylmelamine (HMM) and its derivatives by Dubois, J, Arnould, R, Abikhalil, F, Hanocq, M, Atassi, G, Ghanem, G, Libert, A, Lejeune, F J

“…The cytotoxicity of hexamethylmelamine (HMM) and its metabolites was investigated in three murine cell lines: one in vitro naturally sensitive to HMM (RC) and…”
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Naphthylisoquinoline alkaloids exhibit strong growth-inhibiting activities against Plasmodium falciparum and P. berghei in vitro--structure-activity relationships of dioncophylline C by François, G, Timperman, G, Holenz, J, Aké Assi, L, Geuder, T, Maes, L, Dubois, J, Hanocq, M, Bringmann, G

“…The growth-inhibiting activities of naturally occurring naphthylisoquinoline alkaloids against asexual blood stages of Plasmodium falciparum (NF 54, clone…”
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