Search Results - "HANNA, M. G. JR"
-
1
Delayed cutaneous hypersensitivity to autologous tumor cells in colorectal cancer patients immunized with an autologous tumor cell: Bacillus Calmette-Guérin vaccine
Published in Cancer research (Chicago, Ill.) (01-04-1984)“…The principles and procedures of active specific immunotherapy developed from studies with the inbred guinea pig hepatocarcinoma model were used as the basis…”
Get full text
Journal Article -
2
Adjuvant active specific immunotherapy of stage II and stage III colon cancer with an autologous tumor cell vaccine: first randomized phase III trials show promise
Published in Vaccine (21-03-2001)“…We performed three multi-institutional, prospectively randomized, controlled clinical trials, assessing the therapeutic effect of post-resection adjuvant…”
Get full text
Journal Article Conference Proceeding -
3
Adjuvant active specific immunotherapy for human colorectal cancer: 6.5-year median follow-up of a phase III prospectively randomized trial
Published in Journal of clinical oncology (01-03-1993)“…Patients with colon or rectal cancer were entered onto a prospectively randomized, controlled clinical trial of active specific immunotherapy (ASI) with an…”
Get more information
Journal Article -
4
Preclinical studies on the pharmacokinetic properties of human monoclonal antibodies to colorectal cancer and their use for detection of tumors
Published in Cancer research (Chicago, Ill.) (01-08-1988)“…We studied the pharmacokinetic properties of two human monoclonal antibodies to colon carcinoma cells and their ability to detect tumors in nude mice bearing…”
Get full text
Journal Article -
5
A diagnostic-prognostic test for bladder cancer using a monoclonal antibody-based enzyme-linked immunoassay for detection of urinary fibrin(ogen) degradation products
Published in Cancer research (Chicago, Ill.) (01-12-1984)“…An enzyme-linked immunosorbent assay (ELISA) using a monoclonal antibody was developed to determine the clinical value of urinary fibrinogen/fibrin degradation…”
Get full text
Journal Article -
6
Radioimmunoscintigraphy of recurrent, metastatic, or occult colorectal cancer with technetium 99m-labeled totally human monoclonal antibody 88BV59: results of pivotal, phase III multicenter studies
Published in Journal of clinical oncology (01-05-1998)“…To assess the performance and potential clinical impact of a totally human monoclonal antibody, 88BV59 (HumaSPECT) (INTRACEL, Corp, Rockville, MD), in 202…”
Get more information
Journal Article -
7
Guinea pig line 10 hepatocarcinoma model: characterization of monoclonal antibody and in vivo effect of unconjugated antibody and antibody conjugated to diphtheria toxin A chain
Published in Cancer research (Chicago, Ill.) (01-09-1983)“…Monoclonal antibodies were raised against the guinea pig line 10 (L10) hepatocarcinoma, and an IgG1-producing hybridoma (D3) was selected for further study. D3…”
Get full text
Journal Article -
8
Immunotherapy of Metastases Enhances Subsequent Chemotherapy
Published in Science (American Association for the Advancement of Science) (23-07-1982)“…In many multimodal therapies of cancer, postsurgical chemotherapy is administered before immunotherapy for treatment of micrometastatic disease. This sequence…”
Get full text
Journal Article -
9
Morphological and functional aspects of active specific immunotherapy of established pulmonary metastases in guinea pigs
Published in Cancer research (Chicago, Ill.) (01-10-1981)“…Using active specific immunotherapy, the authors evaluated the efficacy of syngeneic tumor cell vaccines supplemented with the adjuvant Mycobacterium bovis…”
Get full text
Journal Article -
10
Prospectively randomized trial of adjuvant active-specific immunotherapy for human colorectal cancer
Published in Cancer (15-03-1985)“…Over the last four years a guinea pig model of active-specific immunotherapy (ASI) with a syngeneic tumor cell:bacillus calmette-Guerin (BCG) vaccine was…”
Get more information
Journal Article -
11
Synergistic effects of active specific immunotherapy and chemotherapy in guinea pigs with disseminated cancer
Published in The Journal of immunology (1950) (01-06-1983)“…Sewall Wright strain 2 guinea pigs bearing pulmonary metastases of the syngeneic line 10 (L10) hepatocarcinoma were treated with a vaccine composed of 10(7)…”
Get full text
Journal Article -
12
A key to the backdoor into the castle: The clinical ramifications of immunoediting driven by antigenic competition
Published in Human vaccines & immunotherapeutics (03-07-2017)“…Over the last decade the field of cancer biology has gained considerable data on genomic heterogeneity. This situation creates challenges and possibly…”
Get full text
Journal Article -
13
Active specific immunotherapy for stage II and stage III human colon cancer: a randomised trial
Published in The Lancet (British edition) (30-01-1999)“…Colon cancer is curable by surgery, but cure rate depends on the extent of disease. We investigated whether adjuvant active specific immunotherapy (ASI) with…”
Get full text
Journal Article -
14
Generation of tumor cell-reactive human monoclonal antibodies using peripheral blood lymphocytes from actively immunized colorectal carcinoma patients
Published in Cancer research (Chicago, Ill.) (01-08-1985)“…The use of human monoclonal antibodies (MCA) in the detection and treatment of human cancer has been limited by the apparent scarcity of MCA to tumor cell…”
Get full text
Journal Article -
15
Immunotherapy with autologous tumor cell-BCG vaccine in patients with colon cancer: a prospective study of medical and economic benefits
Published in Vaccine (18-03-2005)“…We have completed a multicenter, randomized controlled phase III clinical trial in Stages II and III colon cancer patients with active specific immunotherapy…”
Get full text
Journal Article Conference Proceeding -
16
Adjuvant Active Specific Immunotherapy for Stage II and III Colon Cancer With an Autologous Tumor Cell Vaccine: Eastern Cooperative Oncology Group Study E5283
Published in Journal of clinical oncology (01-01-2000)“…A randomized phase III clinical trial of adjuvant active specific immunotherapy (ASI) with an autologous tumor cell-bacillus Calmette-Guérin (BCG) vaccine was…”
Get full text
Journal Article -
17
Leukoregulin, a direct-acting anticancer immunological hormone that is distinct from lymphotoxin and interferon
Published in Cancer research (Chicago, Ill.) (01-02-1985)“…Human lymphokine preparations can directly lyse or suppress proliferation of human tumor cells or can enhance the susceptibility of human tumor cells to lysis…”
Get full text
Journal Article -
18
Delayed-type hypersensitivity reactions to tumor-associated antigens in colon carcinoma patients immunized with an autologous tumor cell/Bacillus Calmette-Guérin vaccine
Published in Cancer research (Chicago, Ill.) (01-02-1993)“…Five different colon tumor-associated antigens (CTAA) were tested for their ability to induce an immune response in vivo and in vitro in ten colon carcinoma…”
Get full text
Journal Article -
19
Morphological evidence for the translocation of lysosomal organelles from cytotoxic macrophages into the cytoplasm of tumor target cells
Published in Cancer research (Chicago, Ill.) (01-12-1976)“…In this study we have recorded in detail the morphological sequence of interactions between activated macrophages and tumor target cells in vitro. The study is…”
Get full text
Journal Article -
20
Immunotherapy of established micrometastases with Bacillus Calmette-Guérin tumor cell vaccine
Published in Cancer research (Chicago, Ill.) (01-01-1978)“…We evaluated the use of Bacillus Calmette-Guérin admixed with tumor cells as a vaccine to induce systemic tumor immunity for therapy of subclinical…”
Get full text
Journal Article