Search Results - "HANLEY, J. J"
-
1
Studies in the history of probability and statistics, LI: the first conditional logistic regression
Published in Biometrika (16-10-2024)“…Summary Statisticians and epidemiologists generally cite the publications of Prentice & Breslow (1978) and Breslow et al. (1978) as the first description and…”
Get full text
Journal Article -
2
Analytical study of the accuracy of discrete element simulations
Published in International journal for numerical methods in engineering (06-01-2017)“…Summary The numerical errors was used to verify the correctness of key results. The truncation errors, which are larger than the round‐off errors by orders of…”
Get full text
Journal Article -
3
Role of ion channels and transporters in cell migration
Published in Physiological reviews (01-10-2012)“…Cell motility is central to tissue homeostasis in health and disease, and there is hardly any cell in the body that is not motile at a given point in its life…”
Get full text
Journal Article -
4
Tumor-Intrinsic PD-L1 Signaling in Cancer Initiation, Development and Treatment: Beyond Immune Evasion
Published in Frontiers in oncology (19-09-2018)“…Although the role of PD-L1 in suppressing the anti-tumor immune response is extensively documented, recent discoveries indicate a distinct tumor-intrinsic role…”
Get full text
Journal Article -
5
Warfarin reversal
Published in Journal of clinical pathology (01-11-2004)“…Warfarin is the most commonly used oral anticoagulant in the UK. It is associated with few side effects apart from haemorrhage. The most appropriate way to…”
Get full text
Journal Article Book Review -
6
Effect of Obesity on the Pharmacokinetics of Drugs in Humans
Published in Clinical pharmacokinetics (01-02-2010)“…The prevalence of obesity has dramatically increased in recent years and now includes a significant proportion of the world’s children, adolescents and adults…”
Get full text
Journal Article -
7
Elusive physiological role of prostatic acid phosphatase (PAP): generation of choline for sperm motility via auto-and paracrine cholinergic signaling
Published in Frontiers in physiology (2023)“…Prostatic acid phosphatase (PAP) exists as two splice variants, secreted PAP and transmembrane PAP, the latter of which is implicated in antinociceptive…”
Get full text
Journal Article -
8
Brigatinib Versus Crizotinib in Advanced ALK Inhibitor-Naive ALK-Positive Non-Small Cell Lung Cancer: Second Interim Analysis of the Phase III ALTA-1L Trial
Published in Journal of clinical oncology (01-11-2020)“…Brigatinib, a next-generation anaplastic lymphoma kinase (ALK) inhibitor, demonstrated superior progression-free survival (PFS) and improved health-related…”
Get full text
Journal Article -
9
Long Non-coding RNA NEAT1: A Novel Target for Diagnosis and Therapy in Human Tumors
Published in Frontiers in genetics (15-10-2018)“…The nuclear paraspeckle assembly transcript 1 (NEAT1, a long non-coding RNA) is frequently overexpressed in human tumors, and higher NEAT1 expression is…”
Get full text
Journal Article -
10
Helium, Oxygen, Proton, and Electron (HOPE) Mass Spectrometer for the Radiation Belt Storm Probes Mission
Published in Space science reviews (01-11-2013)“…The HOPE mass spectrometer of the Radiation Belt Storm Probes (RBSP) mission (renamed the Van Allen Probes) is designed to measure the in situ plasma ion and…”
Get full text
Journal Article -
11
Fabric and Effective Stress Distribution in Internally Unstable Soils
Published in Journal of geotechnical and geoenvironmental engineering (01-12-2014)“…AbstractInternal instability is a form of internal erosion in broadly graded cohesionless soils in which fine particles can be eroded at lower hydraulic…”
Get full text
Journal Article -
12
Use of a Real-Time Locating System for Contact Tracing of Health Care Workers During the COVID-19 Pandemic at an Infectious Disease Center in Singapore: Validation Study
Published in Journal of medical Internet research (26-05-2020)“…In early 2020, coronavirus disease (COVID-19) emerged and spread by community and nosocomial transmission. Effective contact tracing of potentially exposed…”
Get full text
Journal Article -
13
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype
Published in Nature cell biology (01-09-2015)“…Senescent cells secrete a combination of factors collectively known as the senescence-associated secretory phenotype (SASP). The SASP reinforces senescence and…”
Get full text
Journal Article -
14
PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells
Published in Cancer cell (09-07-2018)“…Oncogene-induced senescence is a potent tumor-suppressive response. Paradoxically, senescence also induces an inflammatory secretome that promotes…”
Get full text
Journal Article -
15
Exploring lncRNA-Mediated Regulatory Networks in Endometrial Cancer Cells and the Tumor Microenvironment: Advances and Challenges
Published in Cancers (16-02-2019)“…Recent studies have revealed both the promise and challenges of targeting long non-coding RNAs (lncRNAs) to diagnose and treat endometrial cancer (EC). LncRNAs…”
Get full text
Journal Article -
16
Geography of suicide in Japan: spatial patterning and rural–urban differences
Published in Social Psychiatry and Psychiatric Epidemiology (01-05-2021)“…Purpose There are notable geographic variations in incidence rates of suicide both in Japan and globally. Previous studies have found that rurality/urbanity…”
Get full text
Journal Article -
17
B7H3 As a Promoter of Metastasis and Promising Therapeutic Target
Published in Frontiers in oncology (06-07-2018)“…B7H3 (also known as CD276, an immune checkpoint molecule) is aberrantly overexpressed in many types of cancer, and such upregulation is generally associated…”
Get full text
Journal Article -
18
Developmental surface and phonological dyslexia in both Greek and English
Published in Cognition (01-11-2017)“…The hallmark of developmental surface dyslexia in English and French is inaccurate reading of words with atypical spelling-sound correspondences. According to…”
Get full text
Journal Article -
19
Clinical Pharmacology of Ixazomib: The First Oral Proteasome Inhibitor
Published in Clinical pharmacokinetics (01-04-2019)“…Ixazomib, the first oral proteasome inhibitor, is approved in combination with lenalidomide and dexamethasone for the treatment of patients with multiple…”
Get full text
Journal Article -
20
Inference for covariate‐adjusted time‐dependent prognostic accuracy measures
Published in Statistics in medicine (15-10-2023)“…Evaluating the prognostic performance of candidate markers for future disease onset or progression is one of the major goals in medical research. A marker's…”
Get full text
Journal Article