Search Results - "HANGAISHI, Akira"

The effect of iron overload and chelation on erythroid differentiation by Taoka, Kazuki, Kumano, Keiki, Nakamura, Fumihiko, Hosoi, Masataka, Goyama, Susumu, Imai, Yoichi, Hangaishi, Akira, Kurokawa, Mineo

“…We investigated the mechanisms of hematopoietic disorders caused by iron overload and chelation, in particular, the inhibition of erythroblast differentiation…”
Get full text

A robust algorithm for copy number detection using high-density oligonucleotide single nucleotide polymorphism genotyping arrays by NANNYA, Yasuhito, SANADA, Masashi, OGAWA, Seishi, NAKAZAKI, Kumi, HOSOYA, Noriko, LILI WANG, HANGAISHI, Akira, KUROKAWA, Mineo, CHIBA, Shigeru, BAILEY, Dione K, KENNEDY, Giulia C

“…We have developed a robust algorithm for copy number analysis of the human genome using high-density oligonucleotide microarrays containing 116,204…”
Get full text

Prolonged neutropenia is a risk of oral adverse events-related sepsis but is not associated with prognosis of tooth extraction in hematopoietic stem cell transplant recipients: A retrospective study by Shimada, Yasuyuki, Shiko, Yuki, Hangaishi, Akira, Kawasaki, Yohei, Maruoka, Yutaka

“…Although the oral cavity has been identified as a potential site of infection in hematologic malignancies and oral adverse events (OAEs) have been reported to…”
Get full text

Mental foramen in panoramic radiography can be a reference for discrimination of punched-out lesions in the mandible in patients with symptomatic multiple myeloma: A cross-sectional study by Shimada, Yasuyuki, Shiko, Yuki, Nakamura, Fumihiko, Hangaishi, Akira, Kawasaki, Yohei, Maruoka, Yutaka

“…Multiple myeloma (MM) is a hematopoietic malignancy characterized by monoclonal proliferation of plasma cells. MM features bony radiolucencies called…”
Get full text

Gain‐of‐function mutations and copy number increases of Notch2 in diffuse large B‐cell lymphoma by Lee, Suk‐young, Kumano, Keiki, Nakazaki, Kumi, Sanada, Masashi, Matsumoto, Akihiko, Yamamoto, Go, Nannya, Yasuhito, Suzuki, Ritsuro, Ota, Satoshi, Ota, Yasunori, Izutsu, Koji, Sakata‐Yanagimoto, Mamiko, Hangaishi, Akira, Yagita, Hideo, Fukayama, Masashi, Seto, Masao, Kurokawa, Mineo, Ogawa, Seishi, Chiba, Shigeru

“…Signaling through the Notch1 receptor has a pivotal role in early thymocyte development. Gain of Notch1 function results in the development of T‐cell acute…”
Get full text

Autologous hematopoietic cell transplantation for myeloma patients with hepatitis B virus or hepatitis C virus in the era of novel agents by Mizuno, Shohei, Takami, Akiyoshi, Takamatsu, Hiroyuki, Hanamura, Ichiro, Shimazu, Yutaka, Hangaishi, Akira, Tsukada, Nobuhiro, Kako, Shinichi, Kikuchi, Taku, Ota, Shuichi, Shimizu, Hiroaki, Iida, Shinsuke, Yoshioka, Satoshi, Sawa, Masashi, Fukuda, Takahiro, Kanda, Yoshinobu, Atsuta, Yoshiko, Kawamura, Koji

Get full text

Changing trends in the risk factors for second primary malignancies after autologous stem cell transplantation for multiple myeloma before and after the introduction of proteasome inhibitors and immunomodulatory drugs by Takamatsu, Hiroyuki, Matsuda, Tomohiro, Mizuno, Shohei, Takahashi, Tsutomu, Fuchida, Shin-Ichi, Hanamura, Ichiro, Kataoka, Keisuke, Tsukada, Nobuhiro, Matsumoto, Morio, Hangaishi, Akira, Doki, Noriko, Uchida, Naoyuki, Sawa, Masashi, Maruyama, Yumiko, Kurahashi, Shingo, Nagafuji, Koji, Harazaki, Yoriko, Kako, Shinichi, Iida, Shinsuke, Ichinohe, Tatsuo, Kanda, Yoshinobu, Atsuta, Yoshiko, Sunami, Kazutaka

“…The incidence of second primary malignancies (SPM) in long-term survivors of multiple myeloma (MM) is increasing because of increased life expectancy. We…”
Get full text

Monitoring trough concentration of voriconazole is important to ensure successful antifungal therapy and to avoid hepatic damage in patients with hematological disorders by Ueda, Koki, Nannya, Yasuhito, Kumano, Keiki, Hangaishi, Akira, Takahashi, Tsuyoshi, Imai, Yoichi, Kurokawa, Mineo

“…We investigated the role of therapeutic dose monitoring (TDM) in the treatment of fungal infections with voriconazole through 49 analyses of 34 patients who…”
Get full text

Escape hematopoiesis by donor-derived 6pLOH(+) hematopoietic stem cells in a marrow transplant recipient with late graft failure by Hino, Toshiya, Imi, Tatsuya, Hangaishi, Akira, Kamoda, Yoshimasa, Iizuka, Hiromitsu, Hirao, Masako, Kida, Michiko, Tojo, Arinobu, Nakao, Shinji, Usuki, Kensuke

Get full text

Characterization of myeloid neoplasms following allogeneic hematopoietic cell transplantation by Kuno, Masatomo, Yamasaki, Satoshi, Fujii, Nobuharu, Ishida, Yasushi, Fukuda, Takahiro, Kataoka, Keisuke, Uchida, Naoyuki, Katayama, Yuta, Sato, Maho, Onai, Daishi, Miyamoto, Toshihiro, Ota, Shuichi, Yoshioka, Satoshi, Ara, Takahide, Hangaishi, Akira, Hashii, Yoshiko, Onizuka, Makoto, Ichinohe, Tatsuo, Atsuta, Yoshiko, Inamoto, Yoshihiro

“…We compared characteristics of myeloid neoplasms (MNs) following allogeneic hematopoietic cell transplantation (HCT) versus autologous HCT using a Japanese HCT…”
Get full text

Highly Sensitive Method for Genomewide Detection of Allelic Composition in Nonpaired, Primary Tumor Specimens by Use of Affymetrix Single-Nucleotide–Polymorphism Genotyping Microarrays by Yamamoto, Go, Nannya, Yasuhito, Kato, Motohiro, Sanada, Masashi, Levine, Ross L., Kawamata, Norihiko, Hangaishi, Akira, Kurokawa, Mineo, Chiba, Shigeru, Gilliland, D. Gary, Koeffler, H. Phillip, Ogawa, Seishi

“…Loss of heterozygosity (LOH), either with or without accompanying copy-number loss, is a cardinal feature of cancer genomes that is tightly linked to cancer…”
Get full text

The influence of pre-admission antiplatelet and anticoagulation therapy on the illness severity in hospitalized patients with COVID-19 in Japan by Togano, Tomiteru, Uemura, Yukari, Asai, Yusuke, Hayakawa, Kayoko, Matsunaga, Nobuaki, Terada, Mari, Ohtsu, Hiroshi, Suzuki, Setsuko, Toyoda, Ako, Hara, Hisao, Sato, Rubuna, Ishikane, Masahiro, Kinoshita-Iwamoto, Noriko, Hangaishi, Akira, Ohmagari, Norio

“…Many articles have reported that the coronavirus disease 2019 (COVID-19) causes coagulation abnormalities and pulmonary thrombosis, contributing to a poorer…”
Get full text

The safety of plasma apheresis from donors recovering from COVID-19 infection in Japan by Kamo-Imai, Ayumi, Togano, Tomiteru, Sato, Motohiko, Kawakami, Yuiko, Inaba, Kumi, Shimazu, Hiroshi, Igarashi, Saori, Tanaka, Keiko, Terada, Mari, Kinoshita-Iwamoto, Noriko, Saito, Sho, Kutsuna, Satoshi, Hangaishi, Akira, Morioka, Shinichiro, Takahashi, Kenzo, Miyata, Satoshi, Ohmagari, Norio

“…Since 2020, the novel coronavirus infection (COVID-19) has spread globally. A few studies have investigated the safety of COVID-19 convalescent plasma (CCP)…”
Get full text

Efficacy of convalescent plasma therapy for COVID-19 in Japan: An open-label, randomized, controlled trial by Saito, Sho, Kutsuna, Satoshi, Akifumi, Imamura, Hase, Ryota, Oda, Rentaro, Terada, Junko, Shimizu, Yosuke, Uemura, Yukari, Takamatsu, Yuki, Yasuhara, Akemi, Shiratori, Katsuyuki, Satake, Masahiro, Sakamoto, Naoya, Miyazaki, Yasunari, Shimizu, Hidefumi, Togano, Tomiteru, Matsunaga, Akihiro, Okuma, Kazu, Hamaguchi, Isao, Fujisawa, Kyoko, Nagashima, Maki, Ashida, Shinobu, Terada, Mari, Kimura, Akiko, Morioka, Shinichiro, Matsubayashi, Keiji, Tsuno, Nelson Hirokazu, Kojima, Makiko, Kuramitsu, Madoka, Tezuka, Kenta, Ikebe, Emi, Ishizaka, Yukihito, Kenji, Maeda, Hangaishi, Akira, Mikami, Ayako, Sugiura, Wataru, Ohmagari, Norio, Mitsuya, Hiroaki

“…Convalescent plasma is a potential therapeutic option for patients with coronavirus disease 2019 (COVID-19). Despite its use for treating several viral…”
Get full text

Efficacy and Safety of Treatment with Plasma from COVID-19-Recovered Individuals by Terada, Mari, Saito, Sho, Kutsuna, Satoshi, Kinoshita-Iwamoto, Noriko, Togano, Tomiteru, Hangaishi, Akira, Shiratori, Katsuyuki, Takamatsu, Yuki, Maeda, Kenji, Ishizaka, Yukihito, Ohtsu, Hiroshi, Satake, Masahiro, Mitsuya, Hiroaki, Ohmagari, Norio

“…Convalescent plasma therapy, which involves administering plasma from recovered coronavirus disease 2019 (COVID-19) patients to infected individuals, is being…”
Get full text

R‐CHOP‐14 versus R‐CHOP‐14/CHASER for upfront autologous transplantation in diffuse large B‐cell lymphoma: JCOG0908 study by Kagami, Yoshitoyo, Yamamoto, Kazuhito, Shibata, Taro, Tobinai, Kensei, Imaizumi, Yoshitaka, Uchida, Toshiki, Shimada, Kazuyuki, Minauchi, Koichiro, Fukuhara, Noriko, Kobayashi, Hirofumi, Yamauchi, Nobuhiko, Tsujimura, Hideki, Hangaishi, Akira, Tominaga, Ryo, Suehiro, Youko, Yoshida, Shinichiro, Inoue, Yoshiko, Suzuki, Sachiko, Tokuhira, Michihide, Kusumoto, Shigeru, Kuroda, Junya, Yakushijin, Yoshihiro, Takamatsu, Yasushi, Kubota, Yasushi, Nosaka, Kisato, Morishima, Satoko, Nakamura, Shigeo, Ogura, Michinori, Maruyama, Dai, Hotta, Tomomitsu, Morishima, Yasuo, Tsukasaki, Kunihiro, Nagai, Hirokazu

“…The efficiency of upfront consolidation with high‐dose chemotherapy/autologous stem‐cell transplantation (HDCT/ASCT) for newly diagnosed high‐risk diffuse…”
Get full text

A Case of Recurrent Ovarian Cancer and Therapy-Related Acute Myeloid Leukemia Treated with Azacitidine by Ando, Kenju, Shimomura, Akihiko, Nasu, Ryo, Nakanishi, Misao, Kawamura, Yukino, Hangaishi, Akira, Oishi, Hajime, Shimizu, Chikako

“…Abstract Therapy-related myelodysplastic syndrome (tMDS) and acute myeloid leukemia (tAML) are lethal complications of chemotherapy. The incidence rates are…”
Get full text

A novel protocol for de-isolating moderately and severely immunocompromised COVID-19 patients by Kamegai, Kohei, Iwamoto, Noriko, Ishikane, Masahiro, Yamamoto, Kei, Horii, Kumi, Kubota, Shiho, Hangaishi, Akira, Shimazu, Hiroshi, Togano, Tomiteru, Yamashita, Hiroyuki, Yamada, Yasuhide, Ohmagari, Norio

“…Immunocompromised coronavirus disease 2019 patients are at a higher risk of prolonged viral shedding than immunocompetent patients. However, as of August 2023,…”
Get full text

Novel Molecular Pathogenesis and Therapeutic Target in Acute Erythroid Leukemia by Takeda, June, Yoshida, Kenichi, Nannya, Yasuhito, Shih, Lee-Yung, Kon, Ayana, Yoda, Akinori, Ochi, Yotaro, Shiozawa, Yusuke, Yoshizato, Tetsuichi, Kerr, Cassandra M, Shiraishi, Yuichi, Chiba, Kenichi, Nagata, Yasunobu, Hangaishi, Akira, Kitano, Toshiyuki, Ishiyama, Ken, Tsurumi, Hisashi, Miyazaki, Yasushi, Hiramoto, Nobuhiro, Ishikawa, Takayuki, Takaori-Kondo, Akifumi, Nakagawa, Masahiro, Sanada, Masashi, Nakazawa, Hideyuki, Kataoka, Keisuke, Saiki, Ryunosuke, Tanaka, Hiroko, Usuki, Kensuke, Miyawaki, Shuichi, Miyano, Satoru, Ganser, Arnold, Heuser, Michael, Maciejewski, Jaroslaw P., Thol, Felicitas, Makishima, Hideki, Ogawa, Seishi

“…Acute erythroid leukemia (AEL) is a unique subtype of acute myeloid leukemia (AML) characterized by erythroid predominance and dysplasia, which is…”
Get full text

Blimp-1 is a tumor suppressor gene in lymphoid malignancies by Hangaishi, Akira, Kurokawa, Mineo

“…B lymphocyte-induced maturation protein (Blimp-1) is a transcriptional factor, which controls the terminal differentiation of mature B cells to plasma cells…”
Get full text