Search Results - "HANDLEY, V. W"
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The Human Myelin Basic Protein Gene is Included within a 179-Kilobase Transcription Unit: Expression in the Immune and Central Nervous Systems
Published in Proceedings of the National Academy of Sciences - PNAS (15-11-1993)“…Two human Golli (for gene expressed in the oligodendrocyte lineage)-MBP (for myelin basic protein) cDNAs have been isolated from a human oligodendroglioma cell…”
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Expression of myelin protein genes and other myelin components in an oligodendrocytic cell line conditionally immortalized with a temperature-sensitive retrovirus
Published in Journal of neurochemistry (01-02-1993)“…We have conditionally immortalized oligodendrocytes isolated from normal and shiverer primary mouse brain cultures through the use of the retroviral vector…”
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The major myelin protein genes are expressed in the human thymus
Published in Journal of neuroscience research (15-09-1996)“…Demyelinating diseases, such as multiple sclerosis (MS) in man or experimental allergic encephalomyelitis (EAE) in rodents, may include an associated immune…”
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Thymocytes Express the golli Products of the Myelin Basic Protein Gene and Levels of Expression Are Stage Dependent
Published in The Journal of immunology (1950) (15-11-2000)“…The golli products of the myelin basic protein gene have been shown to be expressed in mouse thymus and brain. The full repertoire of thymic cell types…”
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DM20 mRNA splice product of the myelin proteolipid protein gene is expressed in the murine heart
Published in Journal of neuroscience research (01-09-1992)“…Northern blot analysis of poly A(+) RNA isolated from mouse heart revealed the expression of 3.3 and 2.4 kb mRNAs that hybridized with a cDNA for the mouse…”
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Expression of a novel transcript of the myelin basic protein gene
Published in Journal of neurochemistry (01-06-1990)“…A cDNA (M41) corresponding to a mouse myelin basic protein (MBP) mRNA with a longer 5'-untranslated region than predicted from earlier studies of MBP gene…”
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Structure and developmental regulation of Golli-mbp, a 105-kilobase gene that encompasses the myelin basic protein gene and is expressed in cells in the oligodendrocyte lineage in the brain
Published in The Journal of biological chemistry (05-03-1993)“…We have identified a novel transcription unit of 105 kilobases (called the Golli-mbp gene) that encompasses the mouse myelin basic protein (MBP) gene. Three…”
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Isolation and characterization of a cDNA encoding the zebra finch myelin proteolipid protein
Published in Neurochemical research (01-08-1994)“…A cDNA was isolated from a zebra finch telencephalon cDNA library that encodes the myelin proteolipid protein. The clone was 2874 nucleotides long containing…”
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Identification of a New Exon in the Myelin Proteolipid Protein Gene Encoding Novel Protein Isoforms That Are Restricted to the Somata of Oligodendrocytes and Neurons
Published in The Journal of neuroscience (01-10-1999)“…The myelin proteolipid protein (PLP) gene (i.e., the PLP/DM20 gene) has been of some interest because of its role in certain human demyelinating diseases, such…”
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Identification of a protein that interacts with the golli-myelin basic protein and with nuclear LIM interactor in the nervous system
Published in Journal of neuroscience research (15-02-2004)“…The myelin basic protein (MBP) gene encodes the classic MBPs and the golli proteins, which are related structurally to the MBPs but are not components of the…”
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Expression of the myelin proteolipid protein gene in the human fetal thymus
Published in Journal of neuroimmunology (01-07-1996)“…We have analyzed human fetal thymus and spleen for expression of the proteolipid protein (PLP) gene. We demonstrate that the PLP gene is transcribed in both…”
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Altered excitatory amino acid function and morphology of the cerebellum of the spastic Han-Wistar rat
Published in Brain research. Molecular brain research. (01-08-1991)“…A mutant strain of Han-Wistar rat carries an autosomal recessive gene producing spastic paresis which is characterized by ataxia, tremor and hind limb…”
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Structural features of myelin basic protein mRNAs influence their translational efficiencies
Published in Journal of neurochemistry (01-04-1994)“…The myelin basic protein (MBP) gene expresses several alternatively spliced products with the same 5' and 3' untranslated regions (UTRs). It has been reported…”
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Identification of genes in the oligodendrocyte lineage through the analysis of conditionally immortalized cell lines
Published in Developmental neuroscience (2001)“…The mouse oligodendrocyte cell lines, N19 and N20.1, were used as sources of potential stage-specific RNA in order to construct a subtraction library enriched…”
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