Search Results - "HANAOKA, F."

A multistep damage recognition mechanism for global genomic nucleotide excision repair by Sugasawa, K, Okamoto, T, Shimizu, Y, Masutani, C, Iwai, S, Hanaoka, F

“…A mammalian nucleotide excision repair (NER) factor, the XPC-HR23B complex, can specifically bind to certain DNA lesions and initiate the cell-free repair…”
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Conserved XPB Core Structure and Motifs for DNA Unwinding: Implications for Pathway Selection of Transcription or Excision Repair by Fan, Li, Arvai, Andrew S., Cooper, Priscilla K., Iwai, Shigenori, Hanaoka, Fumio, Tainer, John A.

“…The human xeroderma pigmentosum group B (XPB) helicase is essential for transcription, nucleotide excision repair, and TFIIH functional assembly. Here, we…”
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Polymerization by DNA polymerase   is blocked by cis-diamminedichloroplatinum(II) 1,3-d(GpTpG) cross-link: implications for cytotoxic effects in nucleotide excision repair-negative tumor cells by Chijiwa, S., Masutani, C., Hanaoka, F., Iwai, S., Kuraoka, I.

“…cis-Diamminedichloroplatinum(II) (cisplatin) forms DNA adducts that interfere with replication and transcription. The most common adducts formed in vivo are…”
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Novel DNA Microarray System for Analysis of Nascent mRNAs by Ohtsu, Masaya, Kawate, Mika, Fukuoka, Masashi, Gunji, Wataru, Hanaoka, Fumio, Utsugi, Takahiko, Onoda, Fumitoshi, Murakami, Yasufumi

“…Transcriptional activation and repression are a key step in the regulation of all cellular activities. The development of comprehensive analysis methods such…”
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DNA replication SOS polymerases by Hanaoka, Fumio

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Template activating factor I, a novel host factor required to stimulate the adenovirus core DNA replication by Matsumoto, K., Nagata, K., Ui, M., Hanaoka, F.

“…The adenovirus (Ad) genome in virion exists in the form of the Ad core, which is a complex of Ad DNA and viral basic proteins. The Ad core supported only…”
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Identification and characterization of XPC-binding domain of hHR23B by Masutani, Chikahide, Araki, Marito, Sugasawa, Kaoru, van der Spek, Peter J., Yamada, Ayumi, Uchida, Akio, Maekawa, Takafumi, Bootsma, Dirk, Hoeijmakers, Jan H. J., Hanaoka, Fumio

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Two human homologs of Rad23 are functionally interchangeable in complex formation and stimulation of XPC repair activity by Sugasawa, Kaoru, Ng, Jessica M. Y., Masutani, Chikahide, Maekawa, Takafumi, Uchida, Akio, van der Spek, Peter J., Eker, André P. M., Rademakers, Suzanne, Visser, Cécile, Aboussekhra, Abdelilah, Wood, Richard D., Hanaoka, Fumio, Bootsma, Dirk, Hoeijmakers, Jan H. J.

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Cell-free repair of UV-damaged simian virus 40 chromosomes in human cell extracts. I. Development of a cell-free system detecting excision repair of UV-irradiated SV40 chromosomes by SUGASAWA, K, MASUTANI, C, HANAOKA, F

“…Simian virus 40 minichromosomes were irradiated with ultraviolet light and used to study cell-free DNA repair reactions by soluble extracts of…”
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Human immunodeficiency virus type 1 Vpr interacts with HHR23A, a cellular protein implicated in nucleotide excision DNA repair by Withers-Ward, E S, Jowett, J B, Stewart, S A, Xie, Y M, Garfinkel, A, Shibagaki, Y, Chow, S A, Shah, N, Hanaoka, F, Sawitz, D G, Armstrong, R W, Souza, L M, Chen, I S

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Benzimidazolium triflate-activated synthesis of (6–4) photoproduct-containing oligonucleotides and its application by Iwai, Shigenori, Mizukoshi, Toshimi, Fujiwara, Yoshie, Masutani, Chikahide, Hanaoka, Fumio, Hayakawa, Yoshihiro

“…In the solid-phase synthesis of oligonucleotides containing the pyrimidine(6–4)pyrimidone photoproduct using a dinucleotide building block, considerable…”
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Studies of Nematode TFIIE Function Reveal a Link between Ser-5 Phosphorylation of RNA Polymerase II and the Transition from Transcription Initiation to Elongation by Yamamoto, Seiji, Watanabe, Yoshinori, van der Spek, Peter J., Watanabe, Tomomichi, Fujimoto, Hiroyuki, Hanaoka, Fumio, Ohkuma, Yoshiaki

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Molecular cloning of the cDNAs for the four subunits of mouse DNA polymerase alpha-primase complex and their gene expression during cell proliferation and the cell cycle by MIYAZAWA, H, IZUMI, M, TADA, S, TAKADA, R, MASUTANI, M, UI, M, HANAOKA, F

“…The DNA polymerase alpha-primase complex purified from mouse FM3A cells is composed of four polypeptides with molecular masses of 180, 68, 54, and 46 kDa. The…”
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Conformational Change in the Catalytic Site of the Ribonuclease YoeB Toxin by YefM Antitoxin by Kamada, Katsuhiko, Hanaoka, Fumio

“…The eubacterial chromosome encodes various addiction modules that control global levels of translation through RNA degradation. Crystal structures of the…”
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HHR23B, a human Rad23 homolog, stimulates XPC protein in nucleotide excision repair in vitro by Sugasawa, Kaoru, Masutani, Chikahide, Uchida, Akio, Maekawa, Takafumi, Spek, Peter J. van der, Bootsma, Dirk, Hoeijmakers, Jan H. J., Hanaoka, Fumio

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A human homologue of the yeast GST1 gene codes for a GTP‐binding protein and is expressed in a proliferation‐dependent manner in mammalian cells by Hoshino, S., Miyazawa, H., Enomoto, T., Hanaoka, F., Kikuchi, Y., Kikuchi, A., Ui, M.

“…A human homologue (GST1‐Hs) of the yeast GST1 gene that encodes a new GTP‐binding protein essential for the G1‐to‐S phase transition of the cell cycle was…”
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Structure-function analysis of the EF-hand protein centrin-2 for its intracellular localization and nucleotide excision repair by Nishi, Ryotaro, Sakai, Wataru, Tone, Daisuke, Hanaoka, Fumio, Sugasawa, Kaoru

“…Centrin-2 is an evolutionarily conserved, calmodulin-related protein, which is involved in multiple cellular functions including centrosome regulation and…”
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The comings and goings of nucleotide excision repair factors on damaged DNA by Egly, Jean-Marc, Riedl, Thilo, Hanaoka, Fumio

“…To understand the mechanism of nucleotide excision repair (NER), one of the major human DNA repair pathways, we have set up a DNA repair system in which a…”
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Complementation of defective translesion synthesis and UV light sensitivity in xeroderma pigmentosum variant cells by human and mouse DNA polymerase by Yamada, A., Masutani, C., Iwai, S., Hanaoka, F.

“…Defects in the human gene XPV result in the variant form of the genetic disease xeroderma pigmentosum (XP-V). XPV encodes DNA polymerase [eta], a novel DNA…”
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UV-Induced Ubiquitylation of XPC Protein Mediated by UV-DDB-Ubiquitin Ligase Complex by Sugasawa, Kaoru, Okuda, Yuki, Saijo, Masafumi, Nishi, Ryotaro, Matsuda, Noriyuki, Chu, Gilbert, Mori, Toshio, Iwai, Shigenori, Tanaka, Keiji, Tanaka, Kiyoji, Hanaoka, Fumio

“…The xeroderma pigmentosum group C (XPC) protein complex plays a key role in recognizing DNA damage throughout the genome for mammalian nucleotide excision…”
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