Search Results - "HAMORI, T"
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1
New non competitive AMPA antagonists
Published in Bioorganic & medicinal chemistry (01-08-2000)“…New halogen atom substituted 2,3-benzodiazepine derivatives condensed with an azole ring on the seven membered part of the ring system of type 3 and 4 as well…”
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Anxiolytic 2,3-benzodiazepines, their specific binding to the basal ganglia
Published in Progress in neurobiology (01-03-2000)“…Over the past 20 years, several members of the 2,3-benzodiazepine family have been synthesized. Some of these compounds--tofisopam (Grandaxin), girisopam,…”
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3
Structural analogues of some highly active non-competitive AMPA antagonists
Published in Bioorganic & medicinal chemistry letters (01-05-2000)“…Some 5-methyl analogues (14a-e) of the non-competitive AMPA antagonists 3-acylated 1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-4,5-dihydro-3H-2,3-benzodi…”
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Omeprazole and talampanel as two examples of retrometabolic drug design
Published in Pharmazie (01-05-2004)“…The goal of retrometabolic drug design is: "to design safe, locally active compounds with an improved therapeutic index". Here we describe two cases from our…”
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Neuropharmacology of a new psychotropic 2,3-benzodiazepine
Published in Arzneimittel-Forschung (01-10-1987)“…1-(3-Chlorophenyl)-4-methyl-7,8-dimethoxy-5H-2,3-benzodiazepine (GYKI 51189) is a new analogue of tofisopam. Due to the novel chemical structure this molecule…”
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A new psychoactive 5H-2,3-benzodiazepine with a unique spectrum of activity
Published in Arzneimittel-Forschung (01-08-1989)“…The neuropharmacological effects of 1-(4-amino-phenyl)-4-methyl-7,8-dimethoxy-5H-2,3-benzodiazepine (GYKI 52 322) were investigated and compared with those of…”
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Anxiolytic profile of girisopam and GYKI 52,322 (EGIS 6775). Comparison with chlordiazepoxide and buspirone
Published in Acta physiologica Hungarica (1992)“…The anxiolytic action of two 2,3-benzodiazepines: girisopam: GYKI 51,189 (EGIS 5810): (1-(3-chlorophenyl)-4-methyl-7,8-dimethoxy-5H-2,3-benzodiazepine), and…”
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Positive inotropic effects of GYKI-52 713 in conscious and anaesthetized animals
Published in Acta physiologica Hungarica (1990)Get more information
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