Search Results - "HAMILTON, Stanley"

Circulating plasma MiR-141 is a novel biomarker for metastatic colon cancer and predicts poor prognosis by Cheng, Hanyin, Zhang, Lina, Cogdell, David E, Zheng, Hong, Schetter, Aaron J, Nykter, Matti, Harris, Curtis C, Chen, Kexin, Hamilton, Stanley R, Zhang, Wei

“…Colorectal cancer (CRC) remains one of the major cancer types and cancer related death worldwide. Sensitive, non-invasive biomarkers that can facilitate…”
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Extended RAS Gene Mutation Testing in Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy: American Society of Clinical Oncology Provisional Clinical Opinion Update 2015 by Allegra, Carmen J, Rumble, R Bryan, Hamilton, Stanley R, Mangu, Pamela B, Roach, Nancy, Hantel, Alexander, Schilsky, Richard L

“…An American Society of Clinical Oncology Provisional Clinical Opinion (PCO) offers timely clinical direction after publication or presentation of potentially…”
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Hereditary colorectal cancer syndromes: American Society of Clinical Oncology Clinical Practice Guideline endorsement of the familial risk-colorectal cancer: European Society for Medical Oncology Clinical Practice Guidelines by Stoffel, Elena M, Mangu, Pamela B, Gruber, Stephen B, Hamilton, Stanley R, Kalady, Matthew F, Lau, Michelle Wan Yee, Lu, Karen H, Roach, Nancy, Limburg, Paul J

“…To provide recommendations on prevention, screening, genetics, treatment, and management for people at risk for hereditary colorectal cancer (CRC) syndromes…”
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Characterizing the Killer Colorectal Carcinomas by Hamilton, Stanley R.

“…In this issue of Cancer Cell, Yaeger et al. report mutations, copy number variations, and selected rearrangements from a large series of metastatic colorectal…”
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Molecular Landscape and Actionable Alterations in a Genomically Guided Cancer Clinical Trial: National Cancer Institute Molecular Analysis for Therapy Choice (NCI-MATCH) by Flaherty, Keith T, Gray, Robert J, Chen, Alice P, Li, Shuli, McShane, Lisa M, Patton, David, Hamilton, Stanley R, Williams, P Mickey, Iafrate, A John, Sklar, Jeffrey, Mitchell, Edith P, Harris, Lyndsay N, Takebe, Naoko, Sims, David J, Coffey, Brent, Fu, Tony, Routbort, Mark, Zwiebel, James A, Rubinstein, Larry V, Little, Richard F, Arteaga, Carlos L, Comis, Robert, Abrams, Jeffrey S, O'Dwyer, Peter J, Conley, Barbara A

“…Therapeutically actionable molecular alterations are widely distributed across cancer types. The National Cancer Institute Molecular Analysis for Therapy…”
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Molecular Biomarkers for the Evaluation of Colorectal Cancer: Guideline From the American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and the American Society of Clinical Oncology by Sepulveda, Antonia R, Hamilton, Stanley R, Allegra, Carmen J, Grody, Wayne, Cushman-Vokoun, Allison M, Funkhouser, William K, Kopetz, Scott E, Lieu, Christopher, Lindor, Noralane M, Minsky, Bruce D, Monzon, Federico A, Sargent, Daniel J, Singh, Veena M, Willis, Joseph, Clark, Jennifer, Colasacco, Carol, Rumble, R Bryan, Temple-Smolkin, Robyn, Ventura, Christina B, Nowak, Jan A

“…Purpose Molecular testing of colorectal cancers (CRCs) to improve patient care and outcomes of targeted and conventional therapies has been the center of many…”
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Defective Mismatch Repair As a Predictive Marker for Lack of Efficacy of Fluorouracil-Based Adjuvant Therapy in Colon Cancer by SARGENT, Daniel J, MARSONI, Silvia, RIBIC, Christine, GROTHEY, Axel, MOORE, Malcolm, ZANIBONI, Alberto, SEITZ, Jean-Francois, SINICROPE, Frank, GALLINGER, Steven, MONGES, Genevieve, THIBODEAU, Stephen N, LABIANCA, Roberto, HAMILTON, Stanley R, FRENCH, Amy J, KABAT, Brian, FOSTER, Nathan R, TORRI, Valter

“…Prior reports have indicated that patients with colon cancer who demonstrate high-level microsatellite instability (MSI-H) or defective DNA mismatch repair…”
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Nivolumab Is Effective in Mismatch Repair-Deficient Noncolorectal Cancers: Results From Arm Z1D-A Subprotocol of the NCI-MATCH (EAY131) Study by Azad, Nilofer S, Gray, Robert J, Overman, Michael J, Schoenfeld, Jonathan D, Mitchell, Edith P, Zwiebel, James A, Sharon, Elad, Streicher, Howard, Li, Shuli, McShane, Lisa M, Rubinstein, Larry, Patton, David R, Williams, P Mickey, Coffey, Brent, Hamilton, Stanley R, Bahary, Nathan, Suga, J Marie, Hatoum, Hassan, Abrams, Jeffrey S, Conley, Barbara A, Arteaga, Carlos L, Harris, Lyndsay, O'Dwyer, Peter J, Chen, Alice P, Flaherty, Keith T

“…The National Cancer Institute Molecular Analysis for Therapy Choice (NCI-MATCH) trial, the largest national precision oncology study to date (> 1,100 sites) of…”
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Pragmatic issues in biomarker evaluation for targeted therapies in cancer by de Gramont, Armand, Watson, Sarah, Ellis, Lee M., Rodón, Jordi, Tabernero, Josep, de Gramont, Aimery, Hamilton, Stanley R.

“…Key Points Predictive biomarkers are essential tools with regard to personalized medicine and health economics, and are crucial to improve the success rate of…”
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American Society of Clinical Oncology Provisional Clinical Opinion: Testing for KRAS Gene Mutations in Patients With Metastatic Colorectal Carcinoma to Predict Response to Anti–Epidermal Growth Factor Receptor Monoclonal Antibody Therapy by ALLEGROA, Carmen J, MILBURN JESSUP, J, SOMERFIELD, Mark R, HAMILTON, Stanley R, HAMMOND, Elizabeth H, HAYES, Daniel F, MCALLISTER, Pamela K, MORTON, Roscoe F, SCHILSKY, Richard L

“…An American Society of Clinical Oncology (ASCO) provisional clinical opinion (PCO), offers timely clinical direction to ASCO's oncologists following…”
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Increased Risk of Colorectal Cancer Development Among Patients With Serrated Polyps by Erichsen, Rune, Baron, John A, Hamilton-Dutoit, Stephen J, Snover, Dale C, Torlakovic, Emina Emilia, Pedersen, Lars, Frøslev, Trine, Vyberg, Mogens, Hamilton, Stanley R, Sørensen, Henrik Toft

“…Background & Aims Sessile serrated adenomas/polyps (SSA/Ps) and traditional serrated adenomas (TSAs) are now distinguished from hyperplastic polyps and…”
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Validation of Immunohistochemical Assays for Integral Biomarkers in the NCI-MATCH EAY131 Clinical Trial by Khoury, Joseph D, Wang, Wei-Lien, Prieto, Victor G, Medeiros, L Jeffrey, Kalhor, Neda, Hameed, Meera, Broaddus, Russell, Hamilton, Stanley R

“…Biomarkers that guide therapy selection are gaining unprecedented importance as targeted therapy options increase in scope and complexity. In conjunction with…”
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ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal–Anal Task Forces whitepaper by Dasari, Arvind, Morris, Van K., Allegra, Carmen J., Atreya, Chloe, Benson, Al B., Boland, Patrick, Chung, Ki, Copur, Mehmet S., Corcoran, Ryan B., Deming, Dustin A., Dwyer, Andrea, Diehn, Maximilian, Eng, Cathy, George, Thomas J., Gollub, Marc J., Goodwin, Rachel A., Hamilton, Stanley R., Hechtman, Jaclyn F., Hochster, Howard, Hong, Theodore S., Innocenti, Federico, Iqbal, Atif, Jacobs, Samuel A., Kennecke, Hagen F., Lee, James J., Lieu, Christopher H., Lenz, Heinz-Josef, Lindwasser, O. Wolf, Montagut, Clara, Odisio, Bruno, Ou, Fang-Shu, Porter, Laura, Raghav, Kanwal, Schrag, Deborah, Scott, Aaron J., Shi, Qian, Strickler, John H., Venook, Alan, Yaeger, Rona, Yothers, Greg, You, Y. Nancy, Zell, Jason A., Kopetz, Scott

“…An increasing number of studies are describing potential uses of circulating tumour DNA (ctDNA) in the care of patients with colorectal cancer. Owing to this…”
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Phase II Study of AZD4547 in Patients With Tumors Harboring Aberrations in the FGFR Pathway: Results From the NCI-MATCH Trial (EAY131) Subprotocol W by Chae, Young K, Hong, Fangxin, Vaklavas, Christos, Cheng, Heather H, Hammerman, Peter, Mitchell, Edith P, Zwiebel, James A, Ivy, S Percy, Gray, Robert J, Li, Shuli, McShane, Lisa M, Rubinstein, Larry V, Patton, David, Williams, P Mickey, Hamilton, Stanley R, Mansfield, Aaron, Conley, Barbara A, Arteaga, Carlos L, Harris, Lyndsay N, O'Dwyer, Peter J, Chen, Alice P, Flaherty, Keith T

“…NCI-MATCH is a nationwide, histology-agnostic, signal-finding, molecular profile-driven trial for patients with refractory cancers, lymphomas, or myelomas…”
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Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer by Shen, Lanlan, Toyota, Minoru, Kondo, Yutaka, Lin, E, Zhang, Li, Guo, Yi, Hernandez, Natalie Supunpong, Chen, Xinli, Ahmed, Saira, Konishi, Kazuo, Hamilton, Stanley R, Issa, Jean-Pierre J

“…Colon cancer has been viewed as the result of progressive accumulation of genetic and epigenetic abnormalities. However, this view does not fully reflect the…”
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Proliferation, apoptosis and their regulatory protein expression in colorectal adenomas and serrated lesions by Figueiredo, Jane C, Passarelli, Michael N, Wei, Wei, Ahnen, Dennis J, Morris, Jeffrey S, Corley, Lynda, Mehta, Trupti, Bartley, Angela N, McKeown-Eyssen, Gail, Bresalier, Robert S, Barry, Elizabeth L, Goel, Ajay, Hernandez Mesa, Goretti, Hamilton, Stanley R, Baron, John A

“…Adenomas and serrated lesions represent heterogeneous sets of early precursors in the colorectum with varying malignant potential. They are often distinguished…”
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Association of CpG island methylator phenotype and EREG/AREG methylation and expression in colorectal cancer by Lee, Michael S, McGuffey, Elizabeth J, Morris, Jeffrey S, Manyam, Ganiraju, Baladandayuthapani, Veerabahdran, Wei, Wei, Morris, Van K, Overman, Michael J, Maru, Dipen M, Jiang, Zhi-Qin, Hamilton, Stanley R, Kopetz, Scott

“…Background: High EREG and AREG expression, and left-sided primary tumours are associated with superior efficacy of anti-epidermal growth factor receptor (EGFR)…”
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Clinical and Molecular Characteristics of Post-Colonoscopy Colorectal Cancer: A Population-based Study by Stoffel, Elena M, Erichsen, Rune, Frøslev, Trine, Pedersen, Lars, Vyberg, Mogens, Koeppe, Erika, Crockett, Seth D, Hamilton, Stanley R, Sørensen, Henrik T, Baron, John A

“…Background & Aims Colonoscopy provides incomplete protection from colorectal cancer (CRC), but determinants of post-colonoscopy CRC are not well understood. We…”
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Examining plasma microRNA markers for colorectal cancer at different stages by Sun, Yan, Liu, Yuexin, Cogdell, David, Calin, George A, Sun, Baocun, Kopetz, Scott, Hamilton, Stanley R, Zhang, Wei

“…Circulating microRNAs (miRNAs) have emerged as promising biomarkers; however, few miRNAs have been reproducible and can be used in clinical practice. In this…”
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Phase II Study of Copanlisib in Patients With Tumors With PIK3CA Mutations: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol Z1F by Damodaran, Senthil, Zhao, Fengmin, Deming, Dustin A, Mitchell, Edith P, Wright, John J, Gray, Robert J, Wang, Victoria, McShane, Lisa M, Rubinstein, Larry V, Patton, David R, Williams, P Mickey, Hamilton, Stanley R, Suga, Jennifer M, Conley, Barbara A, Arteaga, Carlos L, Harris, Lyndsay N, O'Dwyer, Peter J, Chen, Alice P, Flaherty, Keith T

“…Activating mutations in are observed across multiple tumor types. The NCI-MATCH (EAY131) is a tumor-agnostic platform trial that enrolls patients to targeted…”
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