Search Results - "HAMADA, Noritaka"

Synthesis and Evaluation of Novel Phenylethanolamine Derivatives containing Acetanilides as Potent and Selective β3-Adrenergic Receptor Agonists by Maruyama, Tatsuya, Onda, Kenichi, Hayakawa, Masahiko, Suzuki, Takayuki, Kimizuka, Tetsuya, Matsui, Tetsuo, Takasu, Toshiyuki, Nagase, Itsuro, Hamada, Noritaka, Ohta, Mitsuaki

“…In the search for potent and selective human β3-adrenergic receptor (AR) agonists as potential pharmacotherapies for the treatment of obesity and non-insulin…”
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Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure–activity relationships of pyrimidine-5-carboxamide derivatives by Hisamichi, Hiroyuki, Naito, Ryo, Toyoshima, Akira, Kawano, Noriyuki, Ichikawa, Atsushi, Orita, Akiko, Orita, Masaya, Hamada, Noritaka, Takeuchi, Makoto, Ohta, Mitsuaki, Tsukamoto, Shin-ichi

“…We discovered the 4-anilinopyrimidine-5-carboxamides as novel Syk inhibitors. These compounds showed high selectivity for Syk compared to other kinases, such…”
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Synthesis and evaluation of novel phenylethanolamine derivatives containing acetanilides as potent and selective beta3-adrenergic receptor agonists by Maruyama, Tatsuya, Onda, Kenichi, Hayakawa, Masahiko, Suzuki, Takayuki, Kimizuka, Tetsuya, Matsui, Tetsuo, Takasu, Toshiyuki, Nagase, Itsuro, Hamada, Noritaka, Ohta, Mitsuaki

“…In the search for potent and selective human beta3-adrenergic receptor (AR) agonists as potential pharmacotherapies for the treatment of obesity and…”
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Quantitative Determination of Amorphous Nicardipine Hydrochloride in Long Acting Formula (NIC-LA®) Using Light Anhydrous Silicic Acid by Kohinata, Takeru, Fujii, Mitsuo, Nakamura, Souichiro, Hamada, Noritaka, Yonemochi, Etsuo, Terada, Katsuhide

“…We investigated a method to quantitatively determine amorphous nicardipine hydrochloride (NIC) in the NIC-long acting formula (LA) model formulas prepared…”
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Synthesis and Biological Evaluation of 3-Biphenyl-4-yl-4-phenyl-4 H -1,2,4-triazoles as Novel Glycine Transporter 1 Inhibitors by Sugane, Takashi, Tobe, Takahiko, Hamaguchi, Wataru, Shimada, Itsuro, Maeno, Kyoichi, Miyata, Junji, Suzuki, Takeshi, Kimizuka, Tetsuya, Kohara, Atsuyuki, Morita, Takuma, Doihara, Hitoshi, Saita, Kyouko, Aota, Masaki, Furutani, Masako, Shimada, Yoshiaki, Hamada, Noritaka, Sakamoto, Shuichi, Tsukamoto, Shin-ichi

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Chronic treatment with olanzapine via a novel infusion pump induces adiposity in male rats by Shobo, Miwako, Yamada, Hiroshi, Koakutsu, Akiko, Hamada, Noritaka, Fujii, Masahiro, Harada, Katsuya, Ni, Keni, Matsuoka, Nobuya

“…Clinical use of olanzapine has been suggested to be associated with weight gain and adiposity in schizophrenic patients. While studies in experimental animals…”
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Synthesis and Biological Evaluation of 3-Biphenyl-4-yl-4-phenyl-4H-1,2,4-triazoles as Novel Glycine Transporter 1 Inhibitors by Sugane, Takashi, Tobe, Takahiko, Hamaguchi, Wataru, Shimada, Itsuro, Maeno, Kyoichi, Miyata, Junji, Suzuki, Takeshi, Kimizuka, Tetsuya, Kohara, Atsuyuki, Morita, Takuma, Doihara, Hitoshi, Saita, Kyouko, Aota, Masaki, Furutani, Masako, Shimada, Yoshiaki, Hamada, Noritaka, Sakamoto, Shuichi, Tsukamoto, Shin-ichi

“…We describe the preparation and evaluation of a novel series of glycine transporter 1 (GlyT1) inhibitors derived from a high-throughput screening hit. The SAR…”
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Practical and efficient synthesis of the (R)-atropisomer of a 4-phenyl 1,2,4-triazole derivative as a selective GlyT1 inhibitor by Sugane, Takashi, Hamada, Noritaka, Tobe, Takahiko, Hamaguchi, Wataru, Shimada, Itsuro, Maeno, Kyoichi, Miyata, Junji, Suzuki, Takeshi, Kimizuka, Tetsuya, Sakamoto, Shuichi, Tsukamoto, Shin-ichi

“…Herein we describe a novel and efficient method for synthesizing the (R)-atropisomer of…”
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Design, synthesis, and pharmacological evaluation of N-bicyclo-5-chloro-1H-indole-2-carboxamide derivatives as potent glycogen phosphorylase inhibitors by Onda, Kenichi, Shiraki, Ryota, Ogiyama, Takashi, Yokoyama, Kazuhiro, Momose, Kazuhiro, Katayama, Naoko, Orita, Masaya, Yamaguchi, Tomohiko, Furutani, Masako, Hamada, Noritaka, Takeuchi, Makoto, Okada, Minoru, Ohta, Mitsuaki, Tsukamoto, Shin-ichi

“…As a result of the various N-bicyclo-5-chloro-1H-indole-2-carboxamide derivatives with a hydroxy moiety synthesized in an effort to discover novel glycogen…”
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Synthesis and Evaluation of Novel Phenylethanolamine Derivatives containing Acetanilides as Potent and Selective [beta]3-Adrenergic Receptor Agonists by Maruyama, Tatsuya, Onda, Kenichi, Hayakawa, Masahiko, Suzuki, Takayuki, Kimizuka, Tetsuya, Matsui, Tetsuo, Takasu, Toshiyuki, Nagase, Itsuro, Hamada, Noritaka, Ohta, Mitsuaki

“…In the search for potent and selective human β3-adrenergic receptor (AR) agonists as potential pharmacotherapies for the treatment of obesity and non-insulin…”
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Synthesis and structure–activity relationships of N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}benzamide derivatives as novel CCR3 antagonists by Sato, Ippei, Morihira, Koichiro, Inami, Hiroshi, Kubota, Hirokazu, Morokata, Tatsuaki, Suzuki, Keiko, Hamada, Noritaka, Iura, Yosuke, Nitta, Aiko, Imaoka, Takayuki, Takahashi, Toshiya, Takeuchi, Makoto, Ohta, Mitsuaki, Tsukamoto, Shin-ichi

“…The 6-fluoro-2-naphthylmethyl derivatives were prepared, and their inhibitory activities against CCR3 were evaluated. A novel class of potent CCR3 receptor…”
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Corrigendum to “Synthesis and structure–activity relationships of N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}benzamide derivatives as novel CCR3 antagonists” [Bioorg. Med. Chem. 16 (2008) 144–156] by Sato, Ippei, Morihira, Koichiro, Inami, Hiroshi, Kubota, Hirokazu, Morokata, Tatsuaki, Suzuki, Keiko, Hamada, Noritaka, Iura, Yosuke, Nitta, Aiko, Imaoka, Takayuki, Takahashi, Toshiya, Takeuchi, Makoto, Ohta, Mitsuaki, Tsukamoto, Shin-ichi

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(+)-(2R,5S)-4-[4-Cyano-3-(trifluoromethyl)phenyl]-2,5-dimethyl-N-[6-(trifluoromethyl)pyridin-3- yl]piperazine-1-carboxamide (YM580) as an Orally Potent and Peripherally Selective Nonsteroidal Androgen Receptor Antagonist by Kinoyama, Isao, Taniguchi, Nobuaki, Toyoshima, Akira, Nozawa, Eisuke, Kamikubo, Takashi, Imamura, Masakazu, Matsuhisa, Akira, Samizu, Kiyohiro, Kawanimani, Eiji, Niimi, Tatsuya, Hamada, Noritaka, Koutoku, Hiroshi, Furutani, Takashi, Kudoh, Masafumi, Okada, Minoru, Ohta, Mitsuaki, Tsukamoto, Shin-ichi

“…A novel series of trans-N-aryl-2,5-dimethylpiperazine-1-carboxamide derivatives was synthesized and their androgen receptor (AR) antagonist activities and in…”
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Design, synthesis, and pharmacological evaluation of N-bicyclo-5-chloro-lH-indole-2-carboxamide derivatives as potent glycogen phosphorylase inhibitors by ONDA, Kenichi, SHIRAKI, Ryota, TAKEUCHI, Makoto, OKADA, Minoru, OHTA, Mitsuaki, TSUKAMOTO, Shin-Ichi, OGIYAMA, Takashi, YOKOYAMA, Kazuhiro, MOMOSE, Kazuhiro, KATAYAMA, Naoko, ORITA, Masaya, YAMAGUCHI, Tomohiko, FURUTANI, Masako, HAMADA, Noritaka

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Synthesis and structure-activity relationships of N-{1-[(6-fluoro2-naphthyl)methyl]piperidin-4-yl} benzamide derivatives as novel CCR3 antagonists : Nucleic Acid Modification for Fluoescence-Based Technologies by SATO, Ippei, MORIHIRA, Koichiro, TAKAHASHI, Toshiya, TAKEUCHI, Makoto, OHTA, Mitsuaki, TSUKAMOTO, Shin-Ichi, INAMI, Hiroshi, KUBOTA, Hirokazu, MOROKATA, Tatsuaki, SUZUKI, Keiko, HAMADA, Noritaka, IURA, Yosuke, NITTA, Aiko, IMAOKA, Takayuki

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Design, synthesis, and pharmacological evaluation of N-bicyclo-5-chloro-1 H-indole-2-carboxamide derivatives as potent glycogen phosphorylase inhibitors by Onda, Kenichi, Shiraki, Ryota, Ogiyama, Takashi, Yokoyama, Kazuhiro, Momose, Kazuhiro, Katayama, Naoko, Orita, Masaya, Yamaguchi, Tomohiko, Furutani, Masako, Hamada, Noritaka, Takeuchi, Makoto, Okada, Minoru, Ohta, Mitsuaki, Tsukamoto, Shin-ichi

“…5-Chloro- N-[(5 R)-1,3,6,6-tetrafluoro-5-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl]-1 H-indole-2-carboxamide are potent inhibitors of human liver glycogen…”
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Corrigendum to “Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure–activity relationships of pyrimidine-5-carboxamide derivatives” [Bioorg. Med. Chem. 13 (2005) 4936–4951] by Hisamichi, Hiroyuki, Naito, Ryo, Toyoshima, Akira, Kawano, Noriyuki, Ichikawa, Atsushi, Orita, Akiko, Orita, Masaya, Hamada, Noritaka, Takeuchi, Makoto, Ohta, Mitsuaki, Tsukamoto, Shin-ichi

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Crystallization of Syndiotactic Polystyrene in β-Form. 3. Energetic Analysis of the Incorporation Mechanism of Stacking Faults into the Crystal by Tosaka, Masatoshi, Hamada, Noritaka, Tsuji, Masaki, Kohjiya, Shinzo

“…Crystallization-temperature (T c) dependence of the probability of the presence of stacking faults, p, in the solution-grown β-form single crystal of…”
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Crystallization of Syndiotactic Polystyrene in β-Form. 1. Positional Identification of Stacking Faults in the Solution-Grown Single Crystals by Tosaka, Masatoshi, Hamada, Noritaka, Tsuji, Masaki, Kohjiya, Shinzo, Ogawa, Tetsuya, Isoda, Seiji, Kobayashi, Takashi

“…The locations of the stacking faults in β-form single crystals of syndiotactic polystyrene, which were grown isothermally from a dilute solution at…”
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Crystallization of Syndiotactic Polystyrene in β-Form. 2. Quantification of Stacking Faults in the Solution-Grown Single Crystals by Hamada, Noritaka, Tosaka, Masatoshi, Tsuji, Masaki, Kohjiya, Shinzo, Katayama, Ken-ichi

“…The probability of the presence of stacking faults in the β-form single crystals of syndiotactic polystyrene, which were grown isothermally from a dilute…”
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