Search Results - "HAMADA, Manabu"

The Preparation of Trisubstituted Alkenyl Nucleoside Phosphonates under Ultrasound-Assisted Olefin Cross-Metathesis by Sari, Ozkan, Hamada, Manabu, Roy, Vincent, Nolan, Steven P, Agrofoglio, Luigi A

“…Intermolecular ultrasound-assisted olefin cross-metathesis is reported. This approach allows an easy access to challenging trisubstituted alkenyl nucleoside…”
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Efficacy and Safety of the Traditional Japanese Medicine Keigairengyoto in the Treatment of Acne Vulgaris by Imafuku, Shinichi, Yasumoto, Shinichiro, Tashiro, Kenji, Kokuba, Hisashi, Tokunaga, Tetsuo, Hamada, Manabu, Masaki, Saori, Ito, Kotaro, Yano, Ichiro

“…Several traditional Japanese medicines including Keigairengyoto (KRT) are used to treat acne vulgaris, but there is no robust evidence of their effectiveness…”
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Secondary alcohols act as better nucleophiles than primary alcohols in the lipase-catalyzed regioselective deacylation of dihydroxybenzenes acylated at both phenolic hydroxyls by Miyazawa, Toshifumi, Hamada, Manabu, Morimoto, Ryohei, Murashima, Takashi, Yamada, Takashi

“…Candida antarctica lipase B (CAL-B) was found to be highly regioselective as well as active in the deacylation of resorcinols and hydroquinones acylated at…”
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Synthesis of resveratrol glycosides by cultured plant cells by Shimoda, Kei, Hamada, Manabu, Hamada, Hatsuyuki, Takemoto, Mai, Hamada, Hiroki

“…Incubation of cultured cells of Glycine max with trans-resveratrol gave its 3-O-beta-D- and 4'-O-beta-D-glucosides. Cultured Gossypium hirsutum cells…”
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Examination of spacer effects on stereochemical recognition of a remote sterically hindered chiral center in lipase-catalyzed acylation by Kobayashi, Ryohei, Huang, Hanghang, Hamada, Manabu, Higashi, Toshinori, Shoji, Mitsuru, Sugai, Takeshi

“…[Display omitted] ► Two hydroxyacetate spacers were examined for resolution of hindered alcohols. ► Burkholderia cepacia lipase showed E=22 on racemic…”
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Lipase-catalyzed enantio- and regioselective transformation of 3- epi-shikimic acid derivatives as the key step for the entry of polyoxygenated carbacycles by Hamada, Manabu, Higashi, Toshinori, Shoji, Mitsuru, Umezawa, Kazuo, Sugai, Takeshi

“…[Display omitted] ▶ C. antarctica lipase B worked on an deriv. of methyl (±)-3- epi-shikimate regioselectively with E > 500. Candida antarctica lipase B…”
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Elaboration on the access to ( S)-4-(4-methylbenzyl)oxy-3-hydroxybutanenitrile, a key intermediate for statins, by combining the kinetic resolution of racemate and the recycle of undesired enantiomer by Sakamoto, Maki, Hamada, Manabu, Higashi, Toshinori, Shoji, Mitsuru, Sugai, Takeshi

“…High enantioselectivity ( E 94) was observed in Candida antarctica lipase B-catalyzed hydrolysis of the corresponding acetate of racemic title compound. The…”
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Highly regioselective propanoylation of dihydroxybenzenes mediated by Candida antarctica lipase B in organic solvents by Miyazawa, Toshifumi, Hamada, Manabu, Morimoto, Ryohei, Murashima, Takashi, Yamada, Takashi

“…Candida antarctica lipase B (CAL-B) was found to be a highly active biocatalyst for the direct acylation of the phenolic hydroxyls of substituted hydroquinones…”
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Chemo-Enzymatic Synthesis of Ester-Linked 2-Phenylindole- 3-Carboxaldehyde-Monosaccharide Conjugate as Potential Prodrug by Shimoda, Kei, Hamada, Manabu, Yokoi, Hiroshi, Hamada, Hiroki

“…Chemo-enzymatic synthesis of ester-linked 2-phenylindole-3-carboxaldehyde-glucose conjugate (2-phenylindole-3-carboxyl-10″-O-β-D-glucosyl ester) was achieved…”
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Perioperative Rehabilitation in Collaboration with the Department of Occupational Medicine for Patients with Cholangiocarcinoma: A Case Report by TERAMATSU, Hiroaki, HACHISUKA, Akiko, NAGATA, Masako, KOHI, Shiro, HAMADA, Manabu, KUHARA, Satoshi, TAKEMOTO, Akio, ITOH, Hideaki, SAEKI, Satoru

“…Introduction: Although the number of cancer survivors has increased, the role of physical therapy in return to work (RTW) for employed patients with cancer…”
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A case of genital folliculosebaceous cystic hamartoma with an unique aggregated manifestation by HAMADA, Manabu, KIRYU, Hiromaro, SATOH, Emiko, MOROI, Yoichi, URABE, Kazunori, FURUE, Masutaka

“…ABSTRACT Folliculosebaceous cystic hamartoma (FCH) is a recently recognized cutaneous hamartoma composed of follicular, sebaceous and mesenchymal components,…”
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Chemo-Enzymatic Synthesis of Glycolyl-Ester-Linked Taxol- Monosaccharide Conjugate and Its Drug Delivery System Using Hepatitis B Virus Envelope L Bio-Nanocapsules by Shimoda, Kei, Hamada, Manabu, Seno, Masaharu, Mandai, Tadakatsu, Hamada, Hiroki

“…Chemo-enzymatic synthesis of glycolyl-ester-linked taxol-glucose conjugate, ie, 7-glycolyltaxol 2′-O-α-D-glucoside, was achieved by using α-glucosidase as a…”
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A Case of Varicella‐Associated Idiopathic Thrombocytopenic Purpura in Adulthood by Hamada, Manabu, Yasumoto, Shinichiro, Furue, Masutaka

“…We describe here an adult case of varicella‐associated idiopathic thrombocytopenic purpura (ITP). A 23‐year‐old Japanese male presented with generalized…”
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Pressure cutaneous ulcer over a pacemaker successfully treated with left subcostal transplantation in an extremely thin patient by HAMADA, Manabu, KAYASHIMA, Miki, URYU, Miki, MOROI, Yoichi, URABE, Kazunori, FURUE, Masutaka

“…ABSTRACT Implantation of a permanent cardiac pacemaker is becoming common with the increase in the elderly population. A cutaneous ulcer over the pacemaker is…”
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A Case of Multifocal Lupus Vulgaris that Preceded Pulmonary Tuberculosis in an Immune Compromised Patient by Hamada, Manabu, Urabe, Kazunori, Moroi, Yoichi, Koga, Tetsuya, Takeishi, Masaaki, Fujita, Masaki, Nakanishi, Yoichi, Furue, Masutaka

“…We describe the rare case of a Japanese male with multifocal lupus vulgaris that preceded asymptomatic pulmonary tuberculosis and adult T‐cell…”
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Candida antarctica lipase B-mediated regioselective acylation of dihydroxybenzenes in organic solvents by Miyazawa, Toshifumi, Hamada, Manabu, Morimoto, Ryohei, Maeda, Yuki

“…Candida antarctica lipase B proved to be a highly active biocatalyst for the direct acylation of phenolic hydroxy groups of substituted hydroquinones and…”
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Candida antarctica lipase B-catalyzed regioselective deacylation of dihydroxybenzenes acylated at both phenolic hydroxy groups by Miyazawa, Toshifumi, Hamada, Manabu, Morimoto, Ryohei

“…Candida antarctica lipase B proved to be highly active in the deacylation of substituted hydroquinones and resorcinols acylated at both phenolic hydroxy…”
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Candida antarctica lipase B-catalyzed regioselective deacylation of dihydroxybenzenes acylated at both phenolic hydroxyl groups by Miyazawa, Toshifumi, Hamada, Manabu, Morimoto, Ryohei

“…Candida antarctica lipase B proved to be highly active in the deacylation of substituted hydroquinones and resorcinols acylated at both phenolic hydroxy…”
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Synthesis and broad spectrum antiviral evaluation of bis(POM) prodrugs of novel acyclic nucleosides by Hamada, Manabu, Roy, Vincent, McBrayer, Tamara R., Whitaker, Tony, Urbina-Blanco, Cesar, Nolan, Steven P., Balzarini, Jan, Snoeck, Robert, Andrei, Graciela, Schinazi, Raymond F., Agrofoglio, Luigi A.

“…A series of seventeen hitherto unknown ANP analogs bearing the (E)-but-2-enyl aliphatic side chain and modified heterocyclic base such as cytosine and…”
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A Progression to Dermatofibrosarcoma Protuberans with a Fibrosarcomatous Component: A Special Reference to the Chromosomal Aberrations by Hamada, Manabu, Hirakawa, Naoya, Fukuda, Tashiro, Furue, Masutaka, Hori, Yoshiaki, Tsuneyoshi, Masazumi

“…Dermatofibrosarcoma protuberans (DFSP) with fibrosarcomatous areas (DFSP-FS) is differentiated from ordinary DFSP by its unfavourable prognosis. We carried out…”
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