Search Results - "HALTON, D. E"

Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 protein expression by ELDER, D. J. E, HALTON, D. E, HAGUE, A, PARASKEVA, C

“…Cyclooxygenase (COX) catalyzes the conversion of arachidonic acid to prostaglandin H2. The inducible isoform, COX-2, promotes colorectal tumorigenesis, and…”
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Apoptosis induction and cyclooxygenase‐2 regulation in human colorectal adenoma and carcinoma cell lines by the cyclooxygenase‐2‐selective non‐steroidal anti‐inflammatory drug NS‐398 by Elder, Douglas J.E., Halton, Dawn E., Crew, Tracey E., Paraskeva, Christos

“…We determined the effect of the highly selective cyclooxygenase‐2 (COX‐2) inhibitor NS‐398 on proliferation, apoptosis and COX‐2 regulation in 3 pre‐malignant…”
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The MEK/ERK pathway mediates COX‐2‐selective NSAID‐induced apoptosis and induced COX‐2 protein expression in colorectal carcinoma cells by Elder, Douglas J.E., Halton, Dawn E., Playle, Laura C., Paraskeva, Christos

“…Nonsteroidal antiinflammatory drugs (NSAIDs) can prevent colorectal tumorigenesis in humans and in rodents. In vitro and in vivo studies indicate that one of…”
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