Search Results - "HALPERIN, Julia"
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Reproductive actions of prolactin mediated through short and long receptor isoforms
Published in Molecular and cellular endocrinology (25-01-2014)“…•Independent signaling pathways of short form of prolactin receptor are proposed.•Prolactin is important but not essential for follicular development.•An…”
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Local effect of allopregnanolone in rat ovarian steroidogenesis, follicular and corpora lutea development
Published in Scientific reports (16-03-2024)“…Allopregnanolone (ALLO) is a known neurosteroid and a progesterone metabolite synthesized in the ovary, CNS, PNS, adrenals and placenta. Its role in the…”
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Achieving full-term pregnancy in the vizcacha relies on a reboot of luteal steroidogenesis in mid-gestation (Lagostomus maximus, Rodentia)
Published in PloS one (08-07-2022)“…Reactivation of the hypothalamic-pituitary-ovarian (HPO) axis triggered by the decline in serum progesterone in mid-gestation is an uncommon trait that…”
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Variation in Progesterone Receptors and GnRH Expression in the Hypothalamus of the Pregnant South American Plains Vizcacha, Lagostomus maximus (Mammalia, Rodentia)
Published in Biology of reproduction (01-11-2013)“…In mammals, elevated levels of progesterone (P4) throughout gestation maintain a negative feedback over the hypothalamic-hypophyseal-gonadal (H-H-G) axis,…”
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First record of an infection by tissue cyst-forming coccidia in wild vizcachas (Lagostomus maximus, Rodentia) of Argentina
Published in International journal for parasitology. Parasites and wildlife (01-12-2021)“…Endoparasites of the Sarcocystidae family share the ability to form tissue cysts in their intermediate hosts, ultimately leading to pathogenesis in the…”
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The Stimulation of HSD17B7 Expression by Estradiol Provides a Powerful Feed-Forward Mechanism for Estradiol Biosynthesis in Breast Cancer Cells
Published in Molecular endocrinology (Baltimore, Md.) (01-05-2011)“…Estradiol enhances its own synthesis in breast cancer cells by stimulating transcription of the hsd17b7 gene through ERα activation and NF1 recruitment. Our…”
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Prolactin Signaling through the Short Form of Its Receptor Represses Forkhead Transcription Factor FOXO3 and Its Target Gene Galt Causing a Severe Ovarian Defect
Published in Molecular endocrinology (Baltimore, Md.) (01-02-2008)“…Prolactin (PRL) is a hormone with over 300 biological activities. Although the signaling pathway downstream of the long form of its receptor (RL) has been well…”
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Regulation of Transcription Factors and Repression of Sp1 by Prolactin Signaling Through the Short Isoform of Its Cognate Receptor
Published in Endocrinology (Philadelphia) (01-07-2009)“…Prolactin (PRL) affects the development and function of the reproductive system by binding to two types of receptors, which differ by the size of their…”
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Prolactin signaling through the short isoform of the mouse prolactin receptor regulates DNA binding of specific transcription factors, often with opposite effects in different reproductive issues
Published in Reproductive biology and endocrinology (24-08-2009)“…It has been well established that prolactin (PRL) signals through the long form of its receptor (PRL-RL) and activates the Jak/Stat pathway for transcription…”
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Estradiol affects the expression of essential molecular factors involved in luteinizing hormone secretion in the plains vizcacha
Published in General and comparative endocrinology (01-01-2025)“…[Display omitted] •Significant increment of Sf-1 and Egr-1 at the pituitary of mid-gestating vizcachas.•E2 reverted GnRHR, Egr-1 and Sf-1 increase in pituitary…”
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Corticogenesis and folding process of the neopallium in the South American plains vizcacha, Lagostomus maximus
Published in Journal of comparative neurology (1911) (01-06-2024)“…The plains vizcacha, Lagostomus maximus, is a precocial hystricomorph rodent with a gyrencephalic brain. This work aimed to perform a time‐lapse analysis of…”
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Hypothalamic GnRH expression and pulsatility depends on a balance of prolactin receptors in the plains vizcacha, Lagostomus maximus
Published in Journal of comparative neurology (1911) (01-05-2023)“…In mammals, gestation is considered a physiological hyperprolactinemia status. Prolactin (PRL) is one of the modulators of gonadotropin‐releasing hormone…”
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Distribution of kisspeptin system and its relation with gonadotropin-releasing hormone in the hypothalamus of the South American plains vizcacha, Lagostomus maximus
Published in General and comparative endocrinology (01-02-2022)“…•AVPV of vizcacha showed sexual dimorphism with a significant smaller area in males.•AVPV depicted three subpopulations of neurons: double Dyn + NKB+, double…”
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Neurovascular description in the South American plains vizcacha, Lagostomus maximus (Chinchilloidea, Caviomorpha). A study involving evolutionarily related species of Caviomorpha and Muroidea
Published in Anatomical record (Hoboken, N.J. : 2007) (01-03-2024)“…Oxygenated blood is required for the adequate metabolic activity of the brain. This is supplied by the circle of Willis (CoW) and the vertebrobasilar and…”
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PTEN and FOXO3 expression in the prenatal and postnatal human ovary
Published in Journal of assisted reproduction and genetics (01-07-2020)“…Purpose The objective of this study was to analyse the expression and cellular localization of FOXO3, pFOXO3 and PTEN throughout human ovary development both…”
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Pituitary estrogen receptor alpha is involved in luteinizing hormone pulsatility at mid-gestation in the South American plains vizcacha, Lagostomus maximus (Rodentia, Caviomorpha)
Published in General and comparative endocrinology (01-03-2019)“…•The involvement of estrogen receptors on LH surge during gestation was evaluated.•ERα, but not ERβ, showed significant increment from mid-gestation.•LH…”
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Mammary gland-specific regulation of GNRH and GNRH-receptor gene expression is likely part of a local autoregulatory system in female vizcachas (Rodentia: Chinchillidae)
Published in General and comparative endocrinology (15-09-2020)“…•GNRH and GNRHR are transcribed in mammary glands of vizcachas throughout pregnancy and lactation.•GNRH and GNRHR are expressed in the secretory epithelia of…”
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Melatonin is involved in the modulation of the hypothalamic and pituitary activity in the South American plains vizcacha, Lagostomus maximus
Published in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology (2022)“…Melatonin, the key messenger of photoperiodic information, is synthesized in the pineal gland by arylalkylamine N -acetyltransferase enzyme (AANAT). It binds…”
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The key action of estradiol and progesterone enables GnRH delivery during gestation in the South American plains vizcacha, Lagostomus maximus
Published in The Journal of steroid biochemistry and molecular biology (01-06-2020)“…•Pharmacological doses of progesterone (P4) and estradiol (E2) inhibited hypothalamic GnRH expression.•Physiological doses of P4 and E2 differentially altered…”
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Inhibition of MAPK by prolactin signaling through the short form of its receptor in the ovary and decidua: involvement of a novel phosphatase
Published in The Journal of biological chemistry (04-03-2011)“…Prolactin (PRL) is essential for normal reproduction and signals through two types of receptors, the short (PRL-RS) and long (PRL-RL) form. We have previously…”
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