Search Results - "HALLER, DANIEL"

Capecitabine Plus Oxaliplatin Compared With Fluorouracil and Folinic Acid As Adjuvant Therapy for Stage III Colon Cancer by HALLER, Daniel G, TABERNERO, Josep, MAROUN, Jean, DE BRAUD, Filippo, PRICE, Timothy, VAN CUTSEM, Eric, HILL, Mark, GILBERG, Frank, RITTWEGER, Karen, SCHMOLL, Hans-Joachim

“…This multicenter, randomized trial compared capecitabine plus oxaliplatin (XELOX) with bolus fluorouracil (FU) and folinic acid (FA) as adjuvant therapy for…”
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Capecitabine Plus Oxaliplatin Compared With Fluorouracil/Folinic Acid As Adjuvant Therapy for Stage III Colon Cancer: Final Results of the NO16968 Randomized Controlled Phase III Trial by Schmoll, Hans-Joachim, Tabernero, Josep, Maroun, Jean, de Braud, Filippo, Price, Timothy, Van Cutsem, Eric, Hill, Mark, Hoersch, Silke, Rittweger, Karen, Haller, Daniel G

“…To report the final efficacy findings and biomarker analysis from the NO16968 trial comparing bolus fluorouracil/folinic acid (FU/FA) with capecitabine plus…”
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Updated Analysis of SWOG-Directed Intergroup Study 0116: A Phase III Trial of Adjuvant Radiochemotherapy Versus Observation After Curative Gastric Cancer Resection by SMALLEY, Stephen R, BENEDETTI, Jacqueline K, STEMMERMANN, Grant N, BLANKE, Charles D, MACDONALD, John S, HALLER, Daniel G, HUNDAHL, Scott A, ESTES, Norman C, AJANI, Jaffer A, GUNDERSON, Leonard L, GOLDMAN, Bryan, MARTENSON, James A, JESSUP, J. Milburn

“…Surgical resection of gastric cancer has produced suboptimal survival despite multiple randomized trials that used postoperative chemotherapy or more…”
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Inducible directed evolution of complex phenotypes in bacteria by Al’Abri, Ibrahim S, Haller, Daniel J, Li, Zidan, Crook, Nathan

“…Abstract Directed evolution is a powerful method for engineering biology in the absence of detailed sequence-function relationships. To enable directed…”
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Impact of Age on the Efficacy of Newer Adjuvant Therapies in Patients With Stage II/III Colon Cancer: Findings From the ACCENT Database by MCCLEARY, Nadine J, MEYERHARDT, Jeffrey A, SARGENT, Daniel J, GREEN, Erin, YOTHERS, Greg, DE GRAMONT, Aimery, VAN CUTSEM, Eric, O'CONNELL, Michael, TWELVES, Christopher J, SALTZ, Leonard B, HALLER, Daniel G

“…Prior studies have suggested that patients with stage II/III colon cancer receive similar benefit from intravenous (IV) fluoropyrimidine adjuvant therapy…”
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Impact of Patient Factors on Recurrence Risk and Time Dependency of Oxaliplatin Benefit in Patients With Colon Cancer: Analysis From Modern-Era Adjuvant Studies in the Adjuvant Colon Cancer End Points (ACCENT) Database by Shah, Manish A, Renfro, Lindsay A, Allegra, Carmen J, André, Thierry, de Gramont, Aimery, Schmoll, Hans-Joachim, Haller, Daniel G, Alberts, Steven R, Yothers, Greg, Sargent, Daniel J

“…Fluorouracil plus leucovorin (FU + LV) adjuvant chemotherapy reduced the risk of recurrence and death across all time points in a pooled analysis of 20,898…”
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Effect of adjuvant capecitabine or fluorouracil, with or without oxaliplatin, on survival outcomes in stage III colon cancer and the effect of oxaliplatin on post-relapse survival: a pooled analysis of individual patient data from four randomised controlled trials by Schmoll, Hans-Joachim, Prof, Twelves, Chris, Prof, Sun, Weijing, Prof, O'Connell, Michael J, Prof, Cartwright, Thomas, Prof, McKenna, Edward, PharmD, Saif, Muhammad, Prof, Lee, Steve, PhD, Yothers, Greg, Prof, Haller, Daniel, Prof

“…Summary Background Oxaliplatin-based adjuvant therapy is the standard of care for stage III colon cancer. Adjuvant capecitabine with or without oxaliplatin…”
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Future Directions in the Treatment of Neuroendocrine Tumors: Consensus Report of the National Cancer Institute Neuroendocrine Tumor Clinical Trials Planning Meeting by KULKE, Matthew H, SIU, Lillian L, VAN CUTSEM, Eric, PINGPANK, James, OBERG, Kjell, COHEN, Steven J, POSNER, Mitchell C, YAO, James C, TEPPER, Joel E, FISHER, George, JAFFE, Deborah, HALLER, Daniel G, ELLIS, Lee M, BENEDETTI, Jacqueline K, BERGSLAND, Emily K, HOBDAY, Timothy J

“…Neuroendocrine tumors (NETs) arise from a variety of anatomic sites and share the capacity for production of hormones and vasoactive peptides. Because of their…”
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Phase III, Randomized Study of Gemcitabine and Oxaliplatin Versus Gemcitabine (fixed-dose rate infusion) Compared With Gemcitabine (30-minute infusion) in Patients With Pancreatic Carcinoma E6201: A Trial of the Eastern Cooperative Oncology Group by POPLIN, Elizabeth, YANG FENG, CELLA, David, BENSON, Al Bowen, BERLIN, Jordan, ROTHENBERG, Mace L, HOCHSTER, Howard, MITCHELL, Edith, ALBERTS, Steven, O'DWYER, Peter, HALLER, Daniel, CATALANO, Paul

“…Single-agent gemcitabine (GEM) is standard treatment of metastatic pancreatic cancer. Fixed-dose rate (FDR) GEM and GEM plus oxaliplatin have shown promise in…”
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Sex and Adverse Events of Adjuvant Chemotherapy in Colon Cancer: An Analysis of 34 640 Patients in the ACCENT Database by Wagner, Anna D, Grothey, Axel, Andre, Thierry, Dixon, Jesse G, Wolmark, Norman, Haller, Daniel G, Allegra, Carmen J, de Gramont, Aimery, VanCutsem, Eric, Alberts, Steven R, George, Thomas J, O’Connell, Michael J, Twelves, Christopher, Taieb, Julien, Saltz, Leonard B, Blanke, Charles D, Francini, Edoardo, Kerr, Rachel, Yothers, Greg, Seitz, Jean F, Marsoni, Silvia, Goldberg, Richard M, Shi, Qian

“…Abstract Background Adjuvant chemotherapy is a standard treatment option for patients with stage III and high-risk stage II colon cancer. Sex is one of several…”
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Adjuvant Chemoradiotherapy With Epirubicin, Cisplatin, and Fluorouracil Compared With Adjuvant Chemoradiotherapy With Fluorouracil and Leucovorin After Curative Resection of Gastric Cancer: Results From CALGB 80101 (Alliance) by Fuchs, Charles S, Niedzwiecki, Donna, Mamon, Harvey J, Tepper, Joel E, Ye, Xing, Swanson, Richard S, Enzinger, Peter C, Haller, Daniel G, Dragovich, Tomislav, Alberts, Steven R, Bjarnason, Georg A, Willett, Christopher G, Gunderson, Leonard L, Goldberg, Richard M, Venook, Alan P, Ilson, David, O'Reilly, Eileen, Ciombor, Kristen, Berg, David J, Meyerhardt, Jeffrey, Mayer, Robert J

“…Purpose After curative resection of gastric or gastroesophageal junction adenocarcinoma, Intergroup Trial 0116 (Phase III trial of postoperative adjuvant…”
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Hepatocellular Carcinoma: Consensus Recommendations of the National Cancer Institute Clinical Trials Planning Meeting by THOMAS, Melanie B, JAFFE, Deborah, POON, Ronnie, SCHWARTZ, Lawrence, TEPPER, Joel, YAO, Francis, HALLER, Daniel, MOONEY, Margaret, VENOOK, Alan, CHOTI, Michael M, BELGHITI, Jacques, CURLEY, Steven, YUMAN FONG, GORES, Gregory, KERLAN, Robert, MERLE, Phillipe, O'NEIL, Bert

“…Hepatocelluar carcinoma (HCC) is the most common primary malignancy of the liver in adults and the third most common cause of cancer death worldwide. The…”
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Long-Term Results of RTOG Trial 8911 (USA Intergroup 113): A Random Assignment Trial Comparison of Chemotherapy Followed by Surgery Compared With Surgery Alone for Esophageal Cancer by KELSEN, David P, WINTER, Katryn A, WILLETT, Christopher G, GUNDERSON, Leonard L, MORTIMER, Joanne, ESTES, Norman C, HALLER, Daniel G, AJANI, Jaffer A, KOCHA, Walter, MINSKY, Bruce D, ROTH, Jack A

“…We update Radiation Therapy Oncology Group trial 8911 (USA Intergroup 113), a comparison of chemotherapy plus surgery versus surgery alone for patients with…”
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Evidence for Cure by Adjuvant Therapy in Colon Cancer: Observations Based on Individual Patient Data From 20,898 Patients on 18 Randomized Trials by SARGENT, Daniel, SOBRERO, Alberto, FRANCOIS SEITZ, Jean, FRANCINI, Guido, HOLLER, Daniel, YOTHERS, Greg, GOLDBERG, Richard, DE GRAMONT, Aimery, GROTHEY, Axel, O'CONNELL, Michael J, BUYSE, Marc, ANDRE, Thierry, YAN ZHENG, GREEN, Erin, LABIANCA, Roberto, O'CALLAGHAN, Chris

“…Limited data are available on the time course of treatment failures (recurrence and/or death), the nature and duration of adjuvant treatment benefit, and…”
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Prognostic Impact of Early Treatment and Oxaliplatin Discontinuation in Patients With Stage III Colon Cancer: An ACCENT/IDEA Pooled Analysis of 11 Adjuvant Trials by Gallois, Claire, Shi, Qian, Meyers, Jeffrey P, Iveson, Timothy, Alberts, Steven R, de Gramont, Aimery, Sobrero, Alberto F, Haller, Daniel G, Oki, Eiji, Shields, Anthony Frank, Goldberg, Richard M, Kerr, Rachel, Lonardi, Sara, Yothers, Greg, Kelly, Caroline, Boukovinas, Ioannis, Labianca, Roberto, Sinicrope, Frank A, Souglakos, Ioannis, Yoshino, Takayuki, Meyerhardt, Jeffrey A, André, Thierry, Papamichael, Demetris, Taieb, Julien

“…Oxaliplatin-based adjuvant chemotherapy in patients with stage III colon cancer (CC) for 6 months remains a standard in high-risk stage III patients. Data are…”
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A Novel Method of Inducible Directed Evolution to Evolve Complex Phenotypes by Al'Abri, Ibrahim S, Li, Zidan, Haller, Daniel J, Crook, Nathan

“…Directed evolution is a powerful technique for identifying beneficial mutations in defined DNA sequences with the goal of improving desired phenotypes. Recent…”
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Phase II/III Study of Doxorubicin With Fluorouracil Compared With Streptozocin With Fluorouracil or Dacarbazine in the Treatment of Advanced Carcinoid Tumors: Eastern Cooperative Oncology Group Study E1281 by WEIJING SUN, LIPSITZ, Stuart, CATALANO, Paul, MAILLIARD, James A, HALLER, Daniel G

“…Optimal treatments for metastatic carcinoid tumor remain undefined, and the role of chemotherapy for symptomatic patients with progressive disease is…”
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Colon Cancer Survival Is Associated With Decreasing Ratio of Metastatic to Examined Lymph Nodes by BERGER, Adam C, SIGURDSON, Elin R, LEVOYER, Thomas, HANLON, Alexandra, MAYER, Robert J, MACDONALD, John S, CATALANO, Paul J, HALLER, Daniel G

“…Colorectal cancer is the second leading cause of cancer deaths in the United States, with poor survival predicted by regional lymph node (LN) metastasis. The…”
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Targeted therapy for metastatic colorectal cancer by Price, Timothy J., Tang, Monica, Gibbs, Peter, Haller, Daniel G., Peeters, Marc, Arnold, Dirk, Segelov, Eva, Roy, Amitesh, Tebbutt, Niall, Pavlakis, Nick, Karapetis, Chris, Burge, Matthew, Shapiro, Jeremy

“…Introduction: Outcomes in metastatic colorectal cancer are improving, with better understanding and use of targeted therapies. Areas covered: A review of the…”
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American Society of Clinical Oncology Recommendations on Adjuvant Chemotherapy for Stage II Colon Cancer by BENSON, Al B, SCHRAG, Deborah, BROUWERS, Melissa, CHARETTE, Manya, HOLLER, Daniel G, SOMERFIELD, Mark R, COHEN, Alfred M, FIGUEREDO, Alvaro T, FLYNN, Patrick J, KRZYZANOWSKA, Monika K, MAROUN, Jean, MCALLISTER, Pamela, VAN CUTSEM, Eric

“…To address whether all medically fit patients with curatively resected stage II colon cancer should be offered adjuvant chemotherapy as part of routine…”
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