Search Results - "HALLENBECK, P. L"

A novel tumor-specific replication-restricted adenoviral vector for gene therapy of hepatocellular carcinoma by Hallenbeck, P L, Chang, Y N, Hay, C, Golightly, D, Stewart, D, Lin, J, Phipps, S, Chiang, Y L

“…Transducing and distributing a vector throughout a tumor mass are presently insufficient for effective cancer gene therapy. To overcome these difficulties an…”
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H‐2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes by Marks, M.S., Hallenbeck, P.L., Nagata, T., Segars, J.H., Appella, E., Nikodem, V.M., Ozato, K.

“…H‐2RIIBP (RXR beta) is a member of the nuclear hormone receptor superfamily that activates transcription of MHC class I genes in response to retinoic acid…”
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Antiangiogenic gene therapy for cancer via systemic administration of adenoviral vectors expressing secretable endostatin by Chen, C T, Lin, J, Li, Q, Phipps, S S, Jakubczak, J L, Stewart, D A, Skripchenko, Y, Forry-Schaudies, S, Wood, J, Schnell, C, Hallenbeck, P L

“…A growing number of antiangiogenesis strategies have been investigated for the treatment of cancer and other angiogenesis-dependent diseases. One of the most…”
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Adenovirus Type 5 Viral Particles Pseudotyped with Mutagenized Fiber Proteins Show Diminished Infectivity of Coxsackie B-Adenovirus Receptor-Bearing Cells by Jakubczak, J L, Rollence, M L, Stewart, D A, Jafari, J D, Von Seggern, D J, Nemerow, G R, Stevenson, S C, Hallenbeck, P L

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DNA binding and heteromerization of the Drosophila transcription factor chorion factor 1/ultraspiracle by Christianson, A.M.K. (DNX Corporation, Princeton, NJ), King, D.L, Hatzivassiliou, E, Casas, J.E, Hallenbeck, P.L, Nikodem, V.M, Mitsialis, S.A, Kafatos, F.C

“…The Drosophila chorion factor 1/ultraspiracle (CF1/USP) transcription factor, a homologue of the retinoid X receptor, is a developmentally important member of…”
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Heterodimerization of Thyroid Hormone (TH) Receptor with H-2RIIBP (RXBβ) Enhances DNA Binding and TH-Dependent Transcriptional Activation by Hallenbeck, Paul L., Marks, Michael S., Lippoldt, Roland E., Ozato, Keiko, Nikodem, Vera M.

“…Steroid/TH receptors mediate transcriptional induction of promoters containing hormone response elements (HREs) through an unclear mechanism that involves…”
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Roles of CfxA, CfxB, and external electron acceptors in regulation of ribulose 1,5-bisphosphate carboxylase/oxygenase expression in Rhodobacter sphaeroides by HALLENBECK, P. L, LERCHEN, R, HESSLER, P, KAPLAN, S

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Divergent effects of 9-cis-retinoic acid receptor on positive and negative thyroid hormone receptor-dependent gene expression by HALLENBECK, P. L, PHYILLAIER, M, NIKODEM, V. M

“…The thyroid hormone (TH)-inducible expression of some genes has recently been shown to be enhanced by 9-cis-retinoic acid (9-cis-RA) receptor (RXR). This…”
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Phosphoribulokinase activity and regulation of CO2 fixation critical for photosynthetic growth of Rhodobacter sphaeroides by HALLENBECK, P. L, LERCHEN, R, HESSLER, P, KAPLAN, S

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Cloning of the gene for phosphoribulokinase activity from Rhodobacter sphaeroides and its expression in Escherichia coli by HALLENBECK, P. L, KAPLAN, S

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Antitumor efficacy and tumor-selective replication with a single intravenous injection of OAS403, an oncolytic adenovirus dependent on two prevalent alterations in human cancer by Ryan, Patricia C, Jakubczak, John L, Stewart, David A, Hawkins, Lynda K, Cheng, Cheng, Clarke, Lori M, Ganesh, Shanthi, Hay, Carl, Huang, Ying, Kaloss, Michele, Marinov, Anthony, Phipps, Sandrina S, Reddy, P Seshidhar, Shirley, Pamela S, Skripchenko, Yelena, Xu, Ling, Yang, Jingping, Forry-Schaudies, Suzanne, Hallenbeck, Paul L

“…A potentially promising treatment of metastatic cancer is the systemic delivery of oncolytic adenoviruses. This requires engineering viruses which selectively…”
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Targetable gene delivery vectors by Hallenbeck, P L, Stevenson, S C

“…Adenoviral vectors, which have targeting ligands for tumor cells on the capsid, no natural tropism, and carry a therapeutic payload should be constructed soon…”
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Enhanced gene transfer to rabbit jugular veins by an adenovirus containing a cyclic RGD motif in the HI loop of the fiber knob by Hay, C M, De Leon, H, Jafari, J D, Jakubczak, J L, Mech, C A, Hallenbeck, P L, Powell, S K, Liau, G, Stevenson, S C

“…Gene therapy using recombinant adenoviral vectors represents a promising therapeutic tool to prevent vein graft stenosis, the main complication of coronary…”
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A single intravenous injection of oncolytic picornavirus SVV-001 eliminates medulloblastomas in primary tumor-based orthotopic xenograft mouse models by Yu, Litian, Baxter, Patricia A., Zhao, Xiumei, Liu, Zhigang, Wadhwa, Lalita, Zhang, Yujing, Su, Jack MF, Tan, Xiaojie, Yang, Jianhua, Adesina, Adekunle, Perlaky, Lazlo, Hurwitz, Mary, Idamakanti, Neeraja, Police, Seshidhar Reddy, Hallenbeck, Paul L., Blaney, Susan M., Chintagumpala, Murali, Hurwitz, Richard L., Li, Xiao-Nan

“…Difficulties of drug delivery across the blood-brain barrier (BBB) and failure to eliminate cancer stem cells (CSCs) are believed to be the major causes of…”
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Differential 9-cis-retinoic acid-dependent transcriptional activation by murine retinoid X receptor alpha (RXR alpha) and RXR beta. Role of cell type and RXR domains by Hallenbeck, P L, Minucci, S, Lippoldt, R, Phyillaier, M, Horn, V, Ozato, K, Nikodem, V M

“…The 9-cis-retinoic acid (9cRA)-inducible enhancer of the rat cellular retinol-binding protein type II gene (CRBP II) was shown to be differentially regulated…”
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Phase I trial of Seneca Valley Virus (NTX-010), a newly discovered systemically deliverable oncolytic picornavirus, in patients with solid tumors with neuroendocrine features by Rudin, C. M., Lansey, D., Burroughs, K. D., Hales, L. M., Neefe, J. R., Reddy, P. S., Hallenbeck, P. L.

“…Abstract only 18014 Background: NTX-010 is a replication-competent cytolytic picornavirus with selective tropism for cancers with neuroendocrine features…”
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An oncolytic adenovirus selective for retinoblastoma tumor suppressor protein pathway-defective tumors: Dependence on E1A, the E2F-1 promoter, and viral replication for selectivity and efficacy by JAKUBCZAK, John L, RYAN, Patricia, PINKSTAFF, Anne, SHIRLEY, Pamela, SKRIPCHENKO, Yelena, STEWART, David, FORRY-SCHAUDIES, Suzanne, HALLENBECK, Paul L, GORZIGLIA, Mario, CLARKE, Lori, HAWKINS, Lynda K, HAY, Carl, YING HUANG, KALOSS, Michele, MARINOV, Anthony, PHIPPS, Sandrina

“…The use of oncolytic adenoviruses as a cancer therapeutic is dependent on the lytic properties of the viral life cycle, and the molecular differences between…”
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Structural gene regions of Rhobobacter sphaeroides involved in CO2 fixation by HALLENBECK, P. L, KAPLAN, S

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Structural gene regions of Rhodobacter sphaeroides involved in CO2 fixation by Hallenbeck, B L, Kaplan, S

“…From studies conducted in both our laboratory and by Gibson, Tabita and colleagues, as well as drawing on the recent studies with Alcaligenes eutrophus, we…”
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