Search Results - "HAK, Jiri"
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1
Prognosis of children with mixed phenotype acute leukemia treated on the basis of consistent immunophenotypic criteria
Published in Haematologica (Roma) (01-06-2010)“…Mixed phenotype acute leukemia (MPAL) represents a diagnostic and therapeutic dilemma. The European Group for the Immunological Classification of Leukemias…”
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2
Minimal residual disease in peripheral blood at day 15 identifies a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with superior prognosis
Published in Haematologica (Roma) (01-12-2011)“…Most minimal residual disease-directed treatment interventions in current treatment protocols for acute lymphoblastic leukemia are based on bone marrow…”
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3
Venous thromboembolism in adolescents
Published in Acta medica Lékarskí fakulty Univerzity Karlovy v Hradci Králove (2012)“…The incidence of venous thromboembolism (VTE) during childhood is low with two peaks - neonatal and adolescent age. This retrospective study is focused on…”
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4
Health of children born to childhood cancer survivors: Participant characteristics and methods of the Multicenter Offspring Study
Published in Cancer epidemiology (01-12-2021)“…Research on childhood cancer survivor offspring has been limited to genetic disease occurrence, malformations or non-hereditary cancers. However, previous…”
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The Czech National Diamond-Blackfan Anemia Registry: Clinical data and ribosomal protein mutations update
Published in Blood cells, molecules, & diseases (15-04-2012)“…Diamond-Blackfan anemia is a rare inherited bone marrow failure syndrome diagnosed in early infancy that is characterized by a (a) macrocytic anemia with no…”
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6
Phenotype / Genotype Correlations in Diamond-Blackfan Anaemia – An Update From the Czech National DBA Registry
Published in Blood (18-11-2011)“…Abstract 5269 Diamond-Blackfan anaemia (DBA) is a rare congenital red cell aplasia that is also associated with various physical anomalies in 40% of patients…”
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Combination of prednisolone and low dosed dexamethasone exhibits greater in vitro antileukemic activity than equiactive dose of prednisolone and overcomes prednisolone drug resistance in acute childhood lymphoblastic leukemia
Published in Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia (01-09-2014)“…Glucocorticoids, particularly prednisone/ prednisolone and dexamethasone, play a prominent role in the treatment of pediatric patients with acute lymphoblastic…”
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8
Prognostic Impact of Peripheral Blood Involvement during Early Time Points of Childhood ALL Treatment
Published in Blood (16-11-2008)“…Minimal residual disease (MRD) testing performed on bone marrow (BM) samples has become a part of the risk group stratification procedure in several of the…”
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Composition of Cellular Subsets by Flow Cytometry Identifies Differences Between MDS Subtypes and Aplastic Anemia but No Differences Are Identified Between Cases with and without Monosomy 7
Published in Blood (20-11-2009)“…Abstract 3802 Poster Board III-738 Monosomy 7 or del(7q) are frequent cytogenetic abnormalities in children with myelodysplastic syndrome (MDS) and associates…”
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10
Development of treatment and clinical results in childhood acute myeloid leukemia in the Czech Republic
Published in Memo - Magazine of European medical oncology (01-02-2013)“…Purpose Treatment of childhood acute myeloid leukemia (AML) was unified in the year 1993 according to acute myeloid leukemia-Berlin–Frankfurt–Munster (AML-BFM)…”
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High-dose methotrexate in children with acute lymphoblastic leukemia: 7-hydroxymethotrexate systemic exposure and urinary concentrations at the steady state correlate well with those of methotrexate
Published in Arzneimittel-Forschung (01-01-2010)“…The present study evaluated the pharmacokinetics of methotrexate (MTX, CAS 59-05-2) and 7-hydroxymethotrexate (7-OHMTX, CAS 5939-37-7) in children with acute…”
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12
Unusual ocular findings in children's acute leukemia cases
Published in Acta medica Lékarskí fakulty Univerzity Karlovy v Hradci Králove (1997)“…The most frequent ocular findings in acute leukemia cases of children and two of our own observations are presented in this study. Emphasized are all…”
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The prospects for children with acute lymphoblastic leukemia of being cured has increased in the Czech Republic in the 21st century to 90% - outcome of the ALL-IC BFM 2002 trial
Published in Časopis lékařů českých (2015)“…Acute lymphoblastic leukemia (ALL) is the most frequent childhood malignancy. Treatment has been unified in the middle of 1980 in the Czech Republic. In…”
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