Search Results - "HAIFAN ZHANG"
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Photoisomerization, assembling and fluorescence photoswitching behaviors of a water-soluble stiff-stilbene with cucurbit[7]uril
Published in Chinese chemical letters (01-08-2023)“…Photoresponsive supramolecular systems have merited extensive attention for their applications in materials science and life science. Here, we synthesized a…”
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2
Dysregulated proteasome activity and steroid hormone biosynthesis are associated with mortality among patients with acute COVID-19
Published in Journal of translational medicine (04-07-2024)“…The persistence of coronavirus disease 2019 (COVID-19)-related hospitalization severely threatens medical systems worldwide and has increased the need for…”
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3
Effect of built environment on BMI of older adults in regions of different socio-economic statuses
Published in Frontiers in public health (07-07-2023)“…Numerous studies have ignored the influence of underdeveloped urban surroundings on the physical health of China's ageing population. Lanzhou is a typical…”
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4
SPI Implementation Based on M2e Microprocessor
Published in MATEC Web of Conferences (01-01-2018)“…Normally, the computer reads, writes and other control operations on the M2 board through the UART protocol. Our goal is to achieve control of the M2 board…”
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5
The built environment’s nonlinear effects on the elderly’s propensity to walk
Published in Frontiers in ecology and evolution (26-01-2023)“…The increased ageing of the population is a vital and upcoming challenge for China. Walking is one of the easiest and most common forms of exercise for older…”
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6
A Fully Human Recombinant IgG-like Bispecific Antibody to Both the Epidermal Growth Factor Receptor and the Insulin-like Growth Factor Receptor for Enhanced Antitumor Activity
Published in The Journal of biological chemistry (20-05-2005)“…Both the epidermal growth factor receptor (EGFR) and the insulin-like growth factor receptor (IGFR) have been implicated in the tumorigenesis of a variety of…”
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7
A universal combinatorial design of antibody framework to graft distinct CDR sequences: A bioinformatics approach
Published in Proteins, structure, function, and bioinformatics (01-03-2012)“…Antibody (Ab) humanization is crucial to generate clinically relevant biologics from hybridoma‐derived monoclonal antibodies (mAbs). In this study, we…”
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8
Tailoring in Vitro Selection for a Picomolar Affinity Human Antibody Directed against Vascular Endothelial Growth Factor Receptor 2 for Enhanced Neutralizing Activity
Published in The Journal of biological chemistry (31-10-2003)“…Vascular endothelial growth factor (VEGF) and its receptors have been implicated in promoting solid tumor growth and metastasis via stimulating…”
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9
Selection of high affinity human neutralizing antibodies to VEGFR2 from a large antibody phage display library for antiangiogenesis therapy
Published in International journal of cancer (20-01-2002)“…Compelling evidence suggests that vascular endothelial growth factor (VEGF) and its receptors play an important role in angiogenesis associated with tumor…”
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10
Simultaneous Blockade of Both the Epidermal Growth Factor Receptor and the Insulin-like Growth Factor Receptor Signaling Pathways in Cancer Cells with a Fully Human Recombinant Bispecific Antibody
Published in The Journal of biological chemistry (23-01-2004)“…Both the epidermal growth factor receptor (EGFR) and the insulin-like growth factor receptor (IGFR) have been implicated in the tumorigenesis of a variety of…”
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11
Development of a Fully Human Anti-PDGFRβ Antibody That Suppresses Growth of Human Tumor Xenografts and Enhances Antitumor Activity of an Anti-VEGFR2 Antibody
Published in Neoplasia (New York, N.Y.) (01-06-2009)“…Platelet-derived growth factor receptor β (PDGFRβ) is upregulated in most of solid tumors. It is expressed by pericytes/smooth muscle cells, fibroblast,…”
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12
Single variable domain antibody as a versatile building block for the construction of IgG-like bispecific antibodies
Published in Journal of immunological methods (10-01-2007)“…Bispecific antibodies (BsAb) have been traditionally utilized to redirect cytotoxic effector cells and agents to kill tumor cells expressing the target…”
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13
Complete inhibition of vascular endothelial growth factor (VEGF) activities with a bifunctional diabody directed against both VEGF kinase receptors, fms-like tyrosine kinase receptor and kinase insert domain-containing receptor
Published in Cancer research (Chicago, Ill.) (01-10-2001)“…Vascular endothelial growth factor (VEGF) binds to and mediates its activity mainly through two tyrosine kinase receptors, VEGF receptor 1 [or fms-like…”
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14
The molecular basis of tamoxifen induction of mouse uterine epithelial cell proliferation
Published in Journal of endocrinology (01-01-2005)“…Tamoxifen, a selective estrogen modulator (SERM) that has found clinical utility in the treatment of breast cancer, is an antagonist in the breast and an…”
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15
Single Variable Domain-IgG Fusion
Published in The Journal of biological chemistry (21-04-2006)“…Both laboratory and early clinical studies to date have demonstrated that bispecific antibodies (BsAb) may have potentially significant application in cancer…”
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16
Fab-scFv fusion protein: an efficient approach to production of bispecific antibody fragments
Published in Journal of immunological methods (15-09-2002)“…The clinical development of bispecific antibodies (BsAb) as therapeutics has been hampered by the difficulty in preparing the materials in sufficient quantity…”
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17
Azepine-Embedded Seco-Hexabenzocoronene-Based Helix Nanographenes: Access to Modification of the Core by N–H Functionalization
Published in Organic letters (10-02-2023)“…Contorted polycyclic aromatic hydrocarbons (PAHs) or nanographenes (NGs) have received increasing attention and are mostly prepared by “bottom-up” strategies…”
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18
Enantioselective Separation of Agricultural Fungicides Based on Chiral Hybrid Nanochannel Membranes
Published in Chemistry of materials (27-02-2024)“…Chiral fungicides have been widely used for disease control in agricultural cultivation due to their advantages of high efficiency, low toxicity, high…”
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The Specific Removal of Perfluorooctanoic Acid Based on Pillar[5]arene-Polymer-Packed Nanochannel Membrane
Published in ACS nano (10-10-2023)“…The conspicuous surface activity and exceptional chemical stability of perfluorooctanoic acid, commonly referred to as PFOA, have led to its extensive…”
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Recent Advances in Stimulus-Responsive Nanocarriers for Pesticide Delivery
Published in Journal of agricultural and food chemistry (11-04-2024)“…In an effort to make pesticide use safer, more efficient, and sustainable, micro-/nanocarriers are increasingly being utilized in agriculture to deliver…”
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