Search Results - "HAIER, R. J"

Positive association between cognitive ability and cortical thickness in a representative US sample of healthy 6 to 18 year-olds by Karama, S., Ad-Dab'bagh, Y., Haier, R.J., Deary, I.J., Lyttelton, O.C., Lepage, C., Evans, A.C.

“…Neuroimaging studies, using various modalities, have evidenced a link between the general intelligence factor ( g) and regional brain function and structure in…”
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Brain networks for working memory and factors of intelligence assessed in males and females with fMRI and DTI by Tang, C.Y., Eaves, E.L., Ng, J.C., Carpenter, D.M., Mai, X., Schroeder, D.H., Condon, C.A., Colom, R., Haier, R.J.

“…Neuro-imaging studies of intelligence implicate the importance of a parietal–frontal network. One unresolved issue is whether this network underlies a general…”
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Neuroimaging of individuals with Down’s syndrome at-risk for dementia: Evidence for possible compensatory events by Haier, R.J., Head, K., Head, E., Lott, I.T.

“…We report functional and structural brain indicators that may precede the onset of dementia in individuals with Down’s syndrome (DS). Middle-aged adults with…”
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Toward a Unified Theory of Narcosis: Brain Imaging Evidence for a Thalamocortical Switch as the Neurophysiologic Basis of Anesthetic-Induced Unconsciousness by Alkire, M.T., Haier, R.J., Fallon, J.H.

“…A unifying theory of general anesthetic-induced unconsciousness must explain the common mechanism through which various anesthetic agents produce…”
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Temporal cortex hypermetabolism in Down syndrome prior to the onset of dementia by HAIER, R. J, ALKIRE, M. T, WHITE, N. S, UNCAPHER, M. R, HEAD, E, LOTT, I. T, COTMAN, C. W

“…Adults with Down syndrome (DS) are at increased risk for dementia and provide an opportunity to identify patterns of brain activity that may precede dementia…”
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Amygdala Activity at Encoding Correlated with Long-Term, Free Recall of Emotional Information by Cahill, Larry, Haier, Richard J., Fallon, James, Alkire, Michael T., Tang, Cheuk, Keator, David, Wu, Joseph, McGaugh, James L.

“…Positron emission tomography of cerebral glucose metabolism in adult human subjects was used to investigate amygdaloid complex (AC) activity associated with…”
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Cerebral metabolism during propofol anesthesia in humans studied with positron emission tomography by ALKIRE, M. T, HAIER, R. J, BARKER, S. J, SHAH, N. K, WU, J. C, KAO, Y. J

“…Although the effects of propofol on cerebral metabolism have been studied in animals, these effects have yet to be directly examined in humans. Consequently,…”
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Correlating in vivo anaesthetic effects with ex vivo receptor density data supports a GABAergic mechanism of action for propofol, but not for isoflurane by Alkire, M.T., Haier, R.J.

“…If the in vivo effects of anaesthesia are mediated through a specific receptor system, then a relationship could exist between the regional changes in brain…”
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Functional brain imaging during anesthesia in humans : Effects of halothane on global and regional cerebral glucose metabolism by ALKIRE, M. T, POMFRETT, C. J. D, HAIER, R. J, GIANZERO, M. V, CHAN, C. M, JACOBSEN, B. P, FALLON, J. H

“…Propofol and isoflurane anesthesia were studied previously with functional brain imaging in humans to begin identifying key brain areas involved with mediating…”
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Positron emission tomography study of regional cerebral metabolism in humans during isoflurane anesthesia by ALKIRE, M. T, HAIER, R. J, SHAH, N. K, ANDERSON, C. T

“…Although the anesthetic effects of the intravenous anesthetic agent propofol have been studied in the living human brain using brain imaging technology, the…”
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Regional glucose metabolic changes after learning a complex visuospatial/motor task: a positron emission tomographic study by Haier, R J, Siegel, Jr, B V, MacLachlan, A, Soderling, E, Lottenberg, S, Buchsbaum, M S

“…Regional cerebral glucose metabolic rate (GMR) quantified with positron emission tomography (PET) with 18-fluoro-2-deoxyglucose (FDG) was measured twice in 8…”
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Decreased anterior cingulate gyrus metabolic rate in schizophrenia by HAZNEDAR, M. M, BUCHSBAUM, M. S, LUU, C, HAZLETT, E. A, SIEGEL, B. V, LOHR, J, WU, J, HAIER, R. J, BUNNEY, W. E

“…OBJECTIVE: This study examined glucose metabolism in the anterior and posterior cingulate cortex in schizophrenia. METHOD: Fifty unmedicated male schizophrenic…”
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Possible compensatory events in adult Down syndrome brain prior to the development of Alzheimer disease neuropathology: targets for nonpharmacological intervention by Head, E, Lott, I T, Patterson, D, Doran, E, Haier, R J

“…Adults with Down syndrome (DS) develop Alzheimer disease (AD) pathology progressively with age but clinical signs of dementia are delayed by at least 10 years…”
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Cortical-striatal-thalamic circuits and brain glucose metabolic activity in 70 unmedicated male schizophrenic patients by Siegel, Jr, B V, Buchsbaum, M S, Bunney, Jr, W E, Gottschalk, L A, Haier, R J, Lohr, J B, Lottenberg, S, Najafi, A, Nuechterlein, K H, Potkin, S G

“…The cortical-striatal-thalamic circuit modulates cognitive processing and thus may be involved in the cognitive dysfunction in schizophrenia. The imaging of…”
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Patterns of cortical activity in schizophrenia by Schroeder, J, Buchsbaum, M S, Siegel, B V, Geider, F J, Haier, R J, Lohr, J, Wu, J, Potkin, S G

“…Eighty-three patients with schizophrenia and 47 healthy controls received positron emission tomography (PET) with 18F-2-deoxyglucose uptake while they were…”
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A controlled trial of desipramine in 18 men with posttraumatic stress disorder by Reist, C, Kauffmann, C D, Haier, R J, Sangdahl, C, DeMet, E M, Chicz-DeMet, A, Nelson, J N

“…Eighteen male U.S. veterans meeting DSM-III criteria for posttraumatic stress disorder (PTSD) completed a 4-week double-blind, crossover study comparing…”
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Glucose metabolic rate in normals and schizophrenics during the Continuous Performance Test assessed by positron emission tomography by Buchsbaum, M S, Nuechterlein, K H, Haier, R J, Wu, J, Sicotte, N, Hazlett, E, Asarnow, R, Potkin, S, Guich, S

“…Local cerebral uptake of glucose labelled with fluorine-18 was measured by positron emission tomography in 13 patients with schizophrenia and 37 right-handed…”
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Effects of clozapine, fluphenazine, and placebo on reaction time measures of attention and sensory dominance in schizophrenia by Zahn, T P, Pickar, D, Haier, R J

“…Two reaction time (RT) paradigms were used to study clozapine's effects on sustained and selective attention compared to fluphenazine and placebo in 25 chronic…”
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PET and MRI of the thalamus in never-medicated patients with schizophrenia by Buchsbaum, M S, Someya, T, Teng, C Y, Abel, L, Chin, S, Najafi, A, Haier, R J, Wu, J, Bunney, Jr, W E

“…This study reports the first paired measurements of glucose metabolism and size of thalamic regions in never-medicated schizophrenic patients using…”
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Sex-Related Difference in Amygdala Activity during Emotionally Influenced Memory Storage by Cahill, Larry, Haier, Richard J., White, Nathan S., Fallon, James, Kilpatrick, Lisa, Lawrence, Chris, Potkin, Steven G., Alkire, Michael T.

“…We tested the possibility suggested by previous imaging studies that amygdala participation in the storage of emotionally influenced memory is differentially…”
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