Search Results - "HAIDER, NIDA"
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Defining the underlying defect in insulin action in type 2 diabetes
Published in Diabetologia (01-05-2021)“…Insulin resistance is one of the earliest defects in the pathogenesis of type 2 diabetes. Over the past 50 years, elucidation of the insulin signalling network…”
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2
Harnessing adipogenesis to prevent obesity
Published in Adipocyte (02-01-2019)“…Obesity and associated metabolic complications, including diabetes, cardiovascular and hepatic diseases, and certain types of cancers, create a major…”
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3
Activation of the PDGFRα-Nrf2 pathway mediates impaired adipocyte differentiation in bone marrow mesenchymal stem cells lacking Nck1
Published in Cell communication and signaling (14-02-2020)“…The limited options to treat obesity and its complications result from an incomplete understanding of the underlying molecular mechanisms regulating white…”
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4
Correction to: Defining the underlying defect in insulin action in type 2 diabetes
Published in Diabetologia (01-06-2022)Get full text
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5
Relationship between empathy and personality traits in students of a Public Sector Medical University
Published in Journal of Rawalpindi Medical College (27-10-2022)“…Introduction: Empathy among medical students and doctors, is rather unexplored part of medical flora and fauna which may vary with each personality. Objective:…”
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6
Nck1 Deficiency Impairs Adipogenesis by Activation of PDGFRα in Preadipocytes
Published in iScience (31-08-2018)“…Obesity results from an excessive expansion of white adipose tissue (WAT), which is still poorly understood from an etiologic-mechanistic perspective. Here, we…”
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Interactions among insulin resistance, epigenetics, and donor sex in gene expression regulation of iPSC-derived myoblasts
Published in The Journal of clinical investigation (01-01-2024)“…About 25% of people in the general population are insulin resistant, increasing the risk for type 2 diabetes (T2D) and metabolic disease. Transcriptomic…”
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Interactions among insulin resistance, epigenetics, and donor sex in gene expression regulation of iPSC-derived myoblasts
Published in The Journal of clinical investigation (16-01-2024)“…About 25% of people in the general population are insulin resistant, increasing the risk for type 2 diabetes (T2D) and metabolic disease. Transcriptomic…”
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44-OR: Cell Intrinsic Alterations in miRNA Expression and Secretion in Muscle in Type 2 Diabetes
Published in Diabetes (New York, N.Y.) (01-06-2024)“…MicroRNAs are important regulators of metabolism in health and disease, and alterations in miRNAs can impact key metabolic pathways/processes, including…”
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10
PSUN312 Interaction Between Insulin Sensitivity Status and Cex in control of Gene Expression in Human iPS Cell-Derived Myoblasts
Published in Journal of the Endocrine Society (01-11-2022)“…Insulin resistance is a major risk factor in the development of type 2 diabetes, metabolic syndrome, polycystic ovarian disease, and many other disorders…”
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Signaling defects associated with insulin resistance in nondiabetic and diabetic individuals and modification by sex
Published in The Journal of clinical investigation (01-11-2021)“…Insulin resistance is present in one-quarter of the general population, predisposing these people to a wide range of diseases. Our aim was to identify…”
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Journal Article -
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Signaling defects associated with insulin resistance in nondiabetic and diabetic individuals and modification by sex
Published in The Journal of clinical investigation (01-11-2021)“…Insulin resistance is present in one-quarter of the general population, predisposing these people to a wide range of diseases. Our aim was to identify…”
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Journal Article -
13
334-OR: Sex Differences in Protein Phosphorylation in Insulin Resistance in Humans at the Cellular Level
Published in Diabetes (New York, N.Y.) (01-06-2021)“…Insulin resistance in muscle precedes and predicts type 2 diabetes in offspring of diabetic parents and is also observed in ~25% of the general population…”
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14
Study of center of mass energy by particles collision in some black holes
Published in Astrophysics and space science (01-07-2013)“…This paper is devoted to the study of particles collision for two well-known black holes. We consider particles moving in equatorial plane and calculate their…”
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15
Effect of Pupil Dilation on Ocular Biometric Measurements in High Myopes: Doi: 10.36351/pjo.v38i2.1353
Published in Pakistan journal of ophthalmolog (Norton, Va.) (31-03-2022)“…Purpose: To determine the effect of pupil dilation on different biometric measurements of eye in high myopes. Study Design: Descriptive observational study…”
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1733-P: Phosphoproteomic Analysis of Insulin Action Using Human IPS-Derived Myoblasts Reveals Important Interactions between Differences Based on Insulin Sensitivity and Sex
Published in Diabetes (New York, N.Y.) (01-06-2020)“…To identify disease-specific indicators associated with insulin resistance by using human induced pluripotent stem cells (iPSCs) as a “disease-in-a-dish”…”
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Nck2 Deficiency in Mice Results in Increased Adiposity Associated With Adipocyte Hypertrophy and Enhanced Adipogenesis
Published in Diabetes (New York, N.Y.) (01-09-2016)“…Obesity results from an excessive expansion of white adipose tissue (WAT) from hypertrophy of preexisting adipocytes and enhancement of precursor…”
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The Role of Nck Adaptor Proteins in White Adipose Tissue Biology
Published 01-01-2019“…Obesity is characterized by excessive expansion of white adipose tissue. Although the underlying mechanisms have been studied in depth in recent years, this…”
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Dissertation -
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Evaluation of Heart Fatty Acid Binding Protein (H-FABP) As A Diagnostic Marker in Acute Coronary Syndrome
Published in Pakistan Journal of Medicine and Dentistry (01-05-2024)“…Background: Heart Type Fatty Acid Binding Protein (H-FABP) is a biomarker suggested for early detection of Acute Coronary Syndrome (ACS). Early diagnosis and…”
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94 - Nck1 is a Critical Regulator of Adipogenesis
Published in Canadian journal of diabetes (01-10-2016)Get full text
Journal Article