Search Results - "HAHN, Ines"

Periodic actin structures in neuronal axons are required to maintain microtubules by Qu, Yue, Hahn, Ines, Webb, Stephen E D, Pearce, Simon P, Prokop, Andreas

“…Axons are cable-like neuronal processes wiring the nervous system. They contain parallel bundles of microtubules as structural backbones, surrounded by…”
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Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons by Hahn, Ines, Voelzmann, Andre, Parkin, Jill, Fülle, Judith B, Slater, Paula G, Lowery, Laura Anne, Sanchez-Soriano, Natalia, Prokop, Andreas

“…The formation and maintenance of microtubules requires their polymerisation, but little is known about how this polymerisation is regulated in cells. Focussing…”
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The model of local axon homeostasis - explaining the role and regulation of microtubule bundles in axon maintenance and pathology by Hahn, Ines, Voelzmann, André, Liew, Yu-Ting, Costa-Gomes, Beatriz, Prokop, Andreas

“…Axons are the slender, cable-like, up to meter-long projections of neurons that electrically wire our brains and bodies. In spite of their challenging…”
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Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex by Qu, Yue, Hahn, Ines, Lees, Meredith, Parkin, Jill, Voelzmann, André, Dorey, Karel, Rathbone, Alex, Friel, Claire T, Allan, Victoria J, Okenve-Ramos, Pilar, Sanchez-Soriano, Natalia, Prokop, Andreas

“…Cortical collapse factors affect microtubule (MT) dynamics at the plasma membrane. They play important roles in neurons, as suggested by inhibition of axon…”
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Cathepsin G and Neutrophil Elastase Play Critical and Nonredundant Roles in Lung-Protective Immunity against Streptococcus pneumoniae in Mice by HAHN, Ines, KLAUS, Anna, WELTE, Tobias, MAUS, Ulrich A, JANZE, Ann-Kathrin, STEINWEDE, Kathrin, NADINE DING, BOHLING, Jennifer, BRUMSHAGEN, Christina, SERRANO, Helene, GAUTHIER, Francis, PATON, James C

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Schlank, a member of the ceramide synthase family controls growth and body fat in Drosophila by Bauer, Reinhard, Voelzmann, André, Breiden, Bernadette, Schepers, Ute, Farwanah, Hany, Hahn, Ines, Eckardt, Franka, Sandhoff, Konrad, Hoch, Michael

“…Ceramide synthases are highly conserved transmembrane proteins involved in the biosynthesis of sphingolipids, which are essential structural components of…”
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Importance of CXC Chemokine Receptor 2 in Alveolar Neutrophil and Exudate Macrophage Recruitment in Response to Pneumococcal Lung Infection by HERBOLD, Wiebke, MAUS, Regina, WINTER, Christine, WELTE, Tobias, MAUS, Ulrich A, HAHN, Ines, DING, Nadine, SRIVASTAVA, Mrigank, CHRISTMAN, John W, MACK, Matthias, REUTERSHAN, Jörg, BRILES, David E, PATON, James C

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The PIKE homolog Centaurin gamma regulates developmental timing in Drosophila by Gündner, Anna Lisa, Hahn, Ines, Sendscheid, Oliver, Aberle, Hermann, Hoch, Michael

“…Phosphoinositide-3-kinase enhancer (PIKE) proteins encoded by the PIKE/CENTG1 gene are members of the gamma subgroup of the Centaurin superfamily of small…”
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Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age- and combination-specific phenotypic profiles in Drosophila by West, Ryan J H, Sharpe, Joanne L, Voelzmann, André, Munro, Anna L, Hahn, Ines, Baines, Richard A, Pickering-Brown, Stuart

“…A large intronic hexanucleotide repeat expansion (GGGGCC) within the C9orf72 (C9orf72-SMCR8 Complex Subunit) locus is the most prevalent genetic cause of both…”
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Context-specific requirements of functional domains of the Spectraplakin Short stop in vivo by Bottenberg, Wolfgang, Sanchez-Soriano, Natalia, Alves-Silva, Juliana, Hahn, Ines, Mende, Michael, Prokop, Andreas

“…Spectraplakins are large multifunctional cytoskeletal interacting molecules implicated in various processes, including gastrulation, wound healing, skin…”
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A conceptual view at microtubule plus end dynamics in neuronal axons by Voelzmann, André, Hahn, Ines, Pearce, Simon P, Sánchez-Soriano, Natalia, Prokop, Andreas

“…Highlights • Axons are the cable-like extensions of neurons which wire the brain. • Axon formation and maintenance requires ordered microtubule (MT) bundles. •…”
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Drosophila Short stop as a paradigm for the role and regulation of spectraplakins by Voelzmann, André, Liew, Yu-Ting, Qu, Yue, Hahn, Ines, Melero, Cristina, Sánchez-Soriano, Natalia, Prokop, Andreas

“…Spectraplakins are evolutionarily well conserved cytoskeletal linker molecules that are true members of three protein families: plakins, spectrins and…”
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Re‐evaluating the actin‐dependence of spectraplakin functions during axon growth and maintenance by Qu, Yue, Alves‐Silva, Juliana, Gupta, Kriti, Hahn, Ines, Parkin, Jill, Sánchez‐Soriano, Natalia, Prokop, Andreas

“…Axons are the long and slender processes of neurons constituting the biological cables that wire the nervous system. The growth and maintenance of axons…”
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Functional and Genetic Analysis of Spectraplakins in Drosophila by Hahn, Ines, Ronshaugen, Matthew, Sánchez-Soriano, Natalia, Prokop, Andreas

“…The cytoskeleton is a dynamic network of filamentous protein polymers required for virtually all cellular processes. It consists of three major classes,…”
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Drosophila CLIP-190 and mammalian CLIP-170 display reduced microtubule plus end association in the nervous system by Beaven, Robin, Dzhindzhev, Nikola S, Qu, Yue, Hahn, Ines, Dajas-Bailador, Federico, Ohkura, Hiroyuki, Prokop, Andreas

“…Axons act like cables, electrically wiring the nervous system. Polar bundles of microtubules (MTs) form their backbones and drive their growth. Plus…”
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The Drosophila Arf GEF Steppke controls MAPK activation in EGFR signaling by Hahn, Ines, Fuss, Bernhard, Peters, Annika, Werner, Tamara, Sieberg, Andrea, Gosejacob, Dominic, Hoch, Michael

“…Guanine nucleotide exchange factors (GEFs) of the cytohesin protein family are regulators of GDP/GTP exchange for members of the ADP ribosylation factor (Arf)…”
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Dendritic cell depletion and repopulation in the lung after irradiation and bone marrow transplantation in mice by Hahn, Ines, Klaus, Anna, Maus, Regina, Christman, John W, Welte, Tobias, Maus, Ulrich A

“…Dendritic cells (DCs) are essential for innate and adaptive immunity, but are purported to exhibit variable radiosensitivity in response to irradiation in…”
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Prominent actin fiber arrays in Drosophila tendon cells represent architectural elements different from stress fibers by Alves-Silva, Juliana, Hahn, Ines, Huber, Olga, Mende, Michael, Reissaus, Andre, Prokop, Andreas

“…Tendon cells are specialized cells of the insect epidermis that connect basally attached muscle tips to the cuticle on their apical surface via prominent…”
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