Search Results - "HAGLUND, Cat M"

Pathogens and polymers: microbe-host interactions illuminate the cytoskeleton by Haglund, Cat M, Welch, Matthew D

“…Intracellular pathogens subvert the host cell cytoskeleton to promote their own survival, replication, and dissemination. Study of these microbes has led to…”
Get full text

Rickettsia Sca2 is a bacterial formin-like mediator of actin-based motility by Welch, Matthew D, Kovar, David R, Choe, Julie E, Haglund, Cat M, Skau, Colleen T

“…Diverse intracellular pathogens subvert the host actin-polymerization machinery to drive movement within and between cells during infection. Rickettsia in the…”
Get full text

Functional genomics of eukaryotic photosynthesis using insertional mutagenesis of Chlamydomonas reinhardtii by Dent, R.M, Haglund, C.M, Chin, B.L, Kobayashi, M.C, Niyogi, K.K

“…The unicellular green alga Chlamydomonas reinhardtii is a widely used model organism for studies of oxygenic photosynthesis in eukaryotes. Here we describe the…”
Get full text

Potent LpxC Inhibitors with In Vitro Activity against Multidrug-Resistant Pseudomonas aeruginosa by Krause, Kevin M, Haglund, Cat M, Hebner, Christy, Serio, Alisa W, Lee, Grace, Nieto, Vincent, Cohen, Frederick, Kane, Timothy R, Machajewski, Timothy D, Hildebrandt, Darrin, Pillar, Chris, Thwaites, Mary, Hall, Danielle, Miesel, Lynn, Hackel, Meredith, Burek, Amanda, Andrews, Logan D, Armstrong, Eliana, Swem, Lee, Jubb, Adrian, Cirz, Ryan T

“…New drugs with novel mechanisms of resistance are desperately needed to address both community and nosocomial infections due to Gram-negative bacteria. One…”
Get full text

Optimization and Mechanistic Characterization of Pyridopyrimidine Inhibitors of Bacterial Biotin Carboxylase by Andrews, Logan D, Kane, Timothy R, Dozzo, Paola, Haglund, Cat M, Hilderbrandt, Darin J, Linsell, Martin S, Machajewski, Timothy, McEnroe, Glen, Serio, Alisa W, Wlasichuk, Kenneth B, Neau, David B, Pakhomova, Svetlana, Waldrop, Grover L, Sharp, Marc, Pogliano, Joe, Cirz, Ryan T, Cohen, Frederick

“…A major challenge for new antibiotic discovery is predicting the physicochemical properties that enable small molecules to permeate Gram-negative bacterial…”
Get full text

Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety by Cohen, Frederick, Aggen, James B., Andrews, Logan D., Assar, Zahra, Boggs, Jen, Choi, Taylor, Dozzo, Paola, Easterday, Ashton N., Haglund, Cat M., Hildebrandt, Darin J., Holt, Melissa C., Joly, Kristin, Jubb, Adrian, Kamal, Zeeshan, Kane, Timothy R., Konradi, Andrei W., Krause, Kevin M., Linsell, Martin S., Machajewski, Timothy D., Miroshnikova, Olga, Moser, Heinz E., Nieto, Vincent, Phan, Thu, Plato, Craig, Serio, Alisa W., Seroogy, Julie, Shakhmin, Anton, Stein, Adam J., Sun, Alex D., Sviridov, Serguei, Wang, Zhan, Wlasichuk, Kenneth, Yang, Wen, Zhou, Xiaoming, Zhu, Hai, Cirz, Ryan T.

“…UDP‐3‐O‐(R‐3‐hydroxymyristoyl)‐N‐acetylglucosamine deacetylase (LpxC) is a Zn2+ deacetylase that is essential for the survival of most pathogenic Gram‐negative…”
Get full text

Defining a core set of actin cytoskeletal proteins critical for actin-based motility of Rickettsia by Serio, Alisa W, Jeng, Robert L, Haglund, Cat M, Reed, Shawna C, Welch, Matthew D

“…Many Rickettsia species are intracellular bacterial pathogens that use actin-based motility for spread during infection. However, while other bacteria assemble…”
Get full text

Functional Genomics of Eukaryotic Photosynthesis Using Insertional Mutagenesis of Chlamydomonas reinhardtii1 by Dent, Rachel M, Haglund, Cat M, Chin, Brian L, Kobayashi, Marilyn C, Niyogi, Krishna K

“…The unicellular green alga Chlamydomonas reinhardtii is a widely used model organism for studies of oxygenic photosynthesis in eukaryotes. Here we describe the…”
Get full text

Functional genomics of eukaryotic photosynthesis using insertional mutagenesis of Chlamydomonas reinhardtii : Chlamydomonas by DENT, Rachel M, HAGLUND, Cat M, CHIN, Brian L, KOBAYASHI, Marilyn C, NIYOGI, Krishna K

Get full text