Search Results - "HAGGITT, RODGER C."

The Role of Cyclooxygenase 2 in Ulcerative Colitis-Associated Neoplasia by Agoff, S. Nicholas, Brentnall, Teresa A., Crispin, David A., Taylor, Shari L., Raaka, Stuart, Haggitt, Rodger C., Reed, Michael W., Afonina, Irina A., Rabinovitch, Peter S., Stevens, Allyn C., Feng, Ziding, Bronner, Mary P.

“…Cyclooxygenase 2 (COX-2) overexpression has been described in sporadic colonic neoplasia, but its role in ulcerative colitis (UC) neoplastic progression…”
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Histopathology of reflux-induced esophageal and supraesophageal injuries by Haggitt, R C

“…As many as half of patients who have symptoms and objective evidence of gastroesophageal reflux disease (GERD) will have normal mucosa or only hyperemia at…”
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Mucosal biopsy diagnosis of colitis: acute self-limited colitis and idiopathic inflammatory bowel disease by Surawicz, C M, Haggitt, R C, Husseman, M, McFarland, L V

“…Rectal biopsy specimen changes distinguish acute self-limited colitis (ASLC) from idiopathic inflammatory bowel disease (IBD). This study aimed to determine…”
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Ursodiol use is associated with lower prevalence of colonic neoplasia in patients with ulcerative colitis and primary sclerosing cholangitis by TUNG, Bruce Y, EMOND, Mary J, HAGGITT, Rodger C, BRONNER, Mary P, KIMMEY, Michael B, KOWDLEY, Kris V, BRENTNALL, Teresa A

“…Patients with ulcerative colitis and primary sclerosing cholangitis are at high risk for colonic dysplasia and cancer. This risk approaches 50% after 25 years…”
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Squamous Overgrowth Is Not a Safety Concern for Photodynamic Therapy for Barrett's Esophagus With High-Grade Dysplasia by Bronner, Mary P, Overholt, Bergein F, Taylor, Shari L, Haggitt, Rodger C, Wang, Kenneth K, Burdick, J. Steven, Lightdale, Charles J, Kimmey, Michael, Nava, Hector R, Sivak, Michael V, Nishioka, Norman, Barr, Hugh, Canto, Marcia I, Marcon, Norman, Pedrosa, Marcos, Grace, Michael, Depot, Michelle

“…Background & Aims Photodynamic therapy with porfimer sodium combined with acid suppression (PHOPDT) is used to treat patients with Barrett's esophagus (BE)…”
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Pancolonic chromosomal instability precedes dysplasia and cancer in ulcerative colitis by RABINOVITCH, P. S, DZIADON, S, BRENTNALL, T. A, EMOND, M. J, CRISPIN, D. A, HAGGITT, R. C, BRONNER, M. P

“…Patients with long-standing ulcerative colitis (UC) are at increased risk for colon cancer. These cancers are thought to arise from preexisting dysplasia in a…”
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Mutations in the p53 gene: an early marker of neoplastic progression in ulcerative colitis by Brentnall, T A, Crispin, D A, Rabinovitch, P S, Haggitt, R C, Rubin, C E, Stevens, A C, Burmer, G C

“…In long-term extensive ulcerative colitis, aneuploidy occurs earlier and loss of heterozygosity for p53 (p53 LOH) later during histological progression towards…”
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An endoscopic biopsy protocol can differentiate high-grade dysplasia from early adenocarcinoma in Barrett's esophagus by Levine, D S, Haggitt, R C, Blount, P L, Rabinovitch, P S, Rusch, V W, Reid, B J

“…Surveying vs. performing resection in patients with high-grade dysplasia in Barrett's esophagus is debated because of concern about the accuracy of endoscopic…”
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Microsatellite instability in nonneoplastic mucosa from patients with chronic ulcerative colitis by BRENTNALL, T. A, CRISPIN, D. A, BRONNER, M. P, CHERIAN, S. P, HUEFFED, M, RABINOVITCH, P. S, RUBIN, C. E, HAGGITT, R. C, BOLAND, C. R

“…Microsatellite instability (MIN) has been detected in many cancer types; however, recently we also observed it in the nonneoplastic but inflammatory setting of…”
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DNA aneuploidy in colonic biopsies predicts future development of dysplasia in ulcerative colitis by Rubin, C E, Haggitt, R C, Burmer, G C, Brentnall, T A, Stevens, A C, Levine, D S, Dean, P J, Kimmey, M, Perera, D R, Rabinovitch, P S

“…The objective of the present study was to determine whether abnormal epithelial DNA content (aneuploidy) in colonic biopsy specimens from ulcerative colitis…”
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Flow-cytometric and histological progression to malignancy in Barrett's esophagus: prospective endoscopic surveillance of a cohort by Reid, B J, Blount, P L, Rubin, C E, Levine, D S, Haggitt, R C, Rabinovitch, P S

“…To determine whether or not flow-cytometric evidence of aneuploidy and increased G2/tetraploid fractions predispose to neoplastic progression in Barrett's…”
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Familial fibrocystic pancreatic atrophy with endocrine cell hyperplasia and pancreatic carcinoma by MECKLER, Kenneth A, BRENTNALL, Teresa A, HAGGITT, Rodger C, CRISPIN, David, BYRD, David R, KIMMEY, Michael B, BRONNER, Mary P

“…Understanding the pathology of familial pancreatic carcinoma may provide important insights into pancreatic tumorigenesis. We now describe in detail the…”
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Neoplasms of the Ampulla of Vater with Concurrent Pancreatic Intraductal Neoplasia: A Histological and Molecular Study by Agoff, S Nicholas, Crispin, David A, Bronner, Mary P, Dail, David H, Hawes, Stephen E, Haggitt, Rodger C

“…Adenoma and adenocarcinoma of the ampulla of Vater are uncommon neoplasms of the gastrointestinal tract. Only one report has analyzed the relationship between…”
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Microsatellite instability and K-ras mutations associated with pancreatic adenocarcinoma and pancreatitis by BRENTNALL, T. A, RU CHEN, LEE, J. G, KIMMEY, M. B, BRONNER, M. P, HAGGITT, R. C, KOWDLEY, K. V, HECKER, L. M, BYRD, D. R

“…ras oncogene mutations and microsatellite instability (MIN) have been described in pancreatic cancer studies from paraffin blocks and fresh frozen tissue. We…”
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Neoplastic progression in ulcerative colitis: histology, DNA content, and loss of a p53 allele by Burmer, G C, Rabinovitch, P S, Haggitt, R C, Crispin, D A, Brentnall, T A, Kolli, V R, Stevens, A C, Rubin, C E

“…Neoplastic progression in patients with chronic ulcerative colitis (UC) is characterized by the development of epithelial dysplasia, which is accompanied by…”
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Pericentral hepatic fibrosis and intracellular hyalin in diabetes mellitus by Falchuk, K R, Fiske, S C, Haggitt, R C, Federman, M, Trey, C

“…Five patients with maturity-onset diabetes mellitus and hepatomegaly were studied. This group in cluded moderately obese females in whom hepatomegaly and…”
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Endoscopic biopsy can detect high-grade dysplasia or early adenocarcinoma in Barrett's esophagus without grossly recognizable neoplastic lesions by Reid, B J, Weinstein, W M, Lewin, K J, Haggitt, R C, VanDeventer, G, DenBesten, L, Rubin, C E

“…There is uncertainty regarding the value of endoscopic biopsy surveillance in Barrett's esophagus because, in retrospective studies, some patients with…”
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Prognostic factors in colorectal carcinomas arising in adenomas: implications for lesions removed by endoscopic polypectomy by Haggitt, R C, Glotzbach, R E, Soffer, E E, Wruble, L D

“…Endoscopic polypectomy has become the preferred technique for the removal of most colorectal adenomas. Whether polypectomy alone or segmental colectomy is the…”
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Idiopathic myointimal hyperplasia of mesenteric veins by Genta, R M, Haggitt, R C

“…Nonthrombotic occlusion or stenosis of the mesenteric veins is a rare cause of intestinal ischemia that usually occurs in association with systemic vasculitis…”
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c-Ki-ras mutations in chronic ulcerative colitis and sporadic colon carcinoma by Burmer, G C, Levine, D S, Kulander, B G, Haggitt, R C, Rubin, C E, Rabinovitch, P S

“…Mutations in the first exon of the c-Ki-ras protooncogene were analyzed in carcinomas and dysplasias from patients with sporadic colon cancer and chronic…”
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