Search Results - "HAGEGE, A. A"

Mapping Myocardial Fiber Orientation Using Echocardiography-Based Shear Wave Imaging by Wei-Ning Lee, Pernot, M., Couade, M., Messas, E., Bruneval, P., Bel, A., Hagege, A. A., Fink, M., Tanter, M.

“…The assessment of disrupted myocardial fiber arrangement may help to understand and diagnose hypertrophic or ischemic cardiomyopathy. We hereby proposed and…”
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X-chromosome inactivation in female patients with Fabry disease by Echevarria, L., Benistan, K., Toussaint, A., Dubourg, O., Hagege, A.A., Eladari, D., Jabbour, F., Beldjord, C., De Mazancourt, P., Germain, D.P.

“…Fabry disease (FD) is an X‐linked genetic disorder caused by the deficient activity of lysosomal α‐galactosidase (α‐Gal). While males are usually severely…”
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The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) Trial : First Randomized Placebo-Controlled Study of Myoblast Transplantation by MENASCHE, Philippe, ALFIERI, Ottavio, LAKE, Stephen, CHATELLIER, Gilles, SOLOMON, Scott, DESNOS, Michel, HAGEGE, Albert A, JANSSENS, Stefan, MCKENNA, William, REICHENSPURNER, Hermann, TRINQUART, Ludovic, VILQUIN, Jean-Thomas, MAROLLEAU, Jean-Pierre, SEYMOUR, Barbara, LARGHERO, Jérome

“…Phase I clinical studies have demonstrated the feasibility of implanting autologous skeletal myoblasts in postinfarction scars. However, they have failed to…”
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Prevalence and clinical phenotype of hereditary transthyretin amyloid cardiomyopathy in patients with increased left ventricular wall thickness by Damy, Thibaud, Costes, Bruno, Hagège, Albert A, Donal, Erwan, Eicher, Jean-Christophe, Slama, Michel, Guellich, Aziz, Rappeneau, Stéphane, Gueffet, Jean-Pierre, Logeart, Damien, Planté-Bordeneuve, Violaine, Bouvaist, Hélène, Huttin, Olivier, Mulak, Geneviève, Dubois-Randé, Jean-Luc, Goossens, Michel, Canoui-Poitrine, Florence, Buxbaum, Joel N

“…Increased left ventricular wall thickness (LVWT) is a common finding in cardiology. It is not known how often hereditary transthyretin-related familial amyloid…”
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Mitral valve disease—morphology and mechanisms by Levine, Robert A., Hagége, Albert A., Judge, Daniel P., Padala, Muralidhar, Dal-Bianco, Jacob P., Aikawa, Elena, Beaudoin, Jonathan, Bischoff, Joyce, Bouatia-Naji, Nabila, Bruneval, Patrick, Butcher, Jonathan T., Carpentier, Alain, Chaput, Miguel, Chester, Adrian H., Clusel, Catherine, Delling, Francesca N., Dietz, Harry C., Dina, Christian, Durst, Ronen, Fernandez-Friera, Leticia, Handschumacher, Mark D., Jensen, Morten O., Jeunemaitre, Xavier P., Marec, Hervé Le, Tourneau, Thierry Le, Markwald, Roger R., Mérot, Jean, Messas, Emmanuel, Milan, David P., Neri, Tui, Norris, Russell A., Peal, David, Perrocheau, Maelle, Probst, Vincent, Pucéat, Michael, Rosenthal, Nadia, Solis, Jorge, Schott, Jean-Jacques, Schwammenthal, Ehud, Slaugenhaupt, Susan A., Song, Jae-Kwan, Yacoub, Magdi H.

“…Key Points Mitral valve disease is a major cause of heart failure and mortality Even in adult life, the mitral valve is a dynamic structure and therapeutically…”
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Aficamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy by Maron, Martin S., Masri, Ahmad, Nassif, Michael E., Barriales-Villa, Roberto, Arad, Michael, Cardim, Nuno, Choudhury, Lubna, Claggett, Brian, Coats, Caroline J., Düngen, Hans-Dirk, Garcia-Pavia, Pablo, Hagège, Albert A., Januzzi, James L., Lee, Matthew M.Y., Lewis, Gregory D., Ma, Chang-Sheng, Michels, Michelle, Olivotto, Iacopo, Oreziak, Artur, Owens, Anjali T., Spertus, John A., Solomon, Scott D., Tfelt-Hansen, Jacob, van Sinttruije, Marion, Veselka, Josef, Watkins, Hugh, Jacoby, Daniel L., Heitner, Stephen B., Kupfer, Stuart, Malik, Fady I., Meng, Lisa, Wohltman, Amy, Abraham, Theodore P.

“…Among patients with symptomatic obstructive hypertrophic cardiomyopathy, treatment with aficamten led to a greater increase in peak oxygen consumption than…”
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Effect of Losartan on Mitral Valve Changes After Myocardial Infarction by Bartko, Philipp E., Dal-Bianco, Jacob P., Guerrero, J. Luis, Beaudoin, Jonathan, Szymanski, Catherine, Kim, Dae-Hee, Seybolt, Margo M., Handschumacher, Mark D., Sullivan, Suzanne, Garcia, Michael L., Titus, James S., Wylie-Sears, Jill, Irvin, Whitney S., Messas, Emmanuel, Hagège, Albert A., Carpentier, Alain, Aikawa, Elena, Bischoff, Joyce, Levine, Robert A.

“…After myocardial infarction (MI), mitral valve (MV) tethering stimulates adaptive leaflet growth, but counterproductive leaflet thickening and fibrosis augment…”
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Skeletal myoblast transplantation in ischemic heart failure : Long-term follow-up of the first phase I cohort of patients by HAGEGE, Albert A, MAROLLEAU, Jean-Pierre, DESNOS, Michel, MENASCHE, Philippe, VILQUIN, Jean-Thomas, ALHERIBERE, Armelle, PEYRARD, Séverine, DUBOC, Denis, ABERGEL, Eric, MESSAS, Emmanuel, MOUSSEAUX, Elie, SCHWARTZ, Ketty

“…Skeletal myoblast (SM) transplantation (Tx) in a post-myocardial infarction (MI) scar experimentally improves left ventricular (LV) ejection fraction (EF)…”
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Composite Cell Sheets A Further Step Toward Safe and Effective Myocardial Regeneration by Cardiac Progenitors Derived From Embryonic Stem Cells by BEL, Alain, PLANAT-BERNARD, Valérie, PEYRARD, Séverine, LARGHERO, Jérôme, POULY, Julia, BINDER, Patrice, GARCIA, Sylvie, SHIMIZU, Tatsuya, SAWA, Yoshiki, OKANO, Teruo, BRUNEVAL, Patrick, DESNOS, Michel, SAITO, Atsuhiro, HAGEGE, Albert A, CASTEILLA, Louis, PUCEAT, Michel, MENASCHE, Philippe, BONNEVIE, Lionel, BELLAMY, Valérie, SABBAH, Laurent, BELLABAS, Linda, BRINON, Benjamin, VANNEAUX, Valérie, PRADEAU, Pascal

“…The safety and efficacy of myocardial regeneration using embryonic stem cells are limited by the risk of teratoma and the high rate of cell death. To address…”
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Feasibility and Performance of Noninvasive Ultrasound Therapy in Patients With Severe Symptomatic Aortic Valve Stenosis: A First-in-Human Study by Messas, Emmanuel, IJsselmuiden, Alexander, Goudot, Guillaume, Vlieger, Selina, Zarka, Samuel, Puymirat, Etienne, Cholley, Bernard, Spaulding, Christian, Hagège, Albert A., Marijon, Eloi, Tanter, Mickael, Bertrand, Benjamin, Rémond, Mathieu C., Penot, Robin, Ren, B., den Heijer, Peter, Pernot, Mathieu, Spaargaren, René

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Transplantation of cardiac-committed mouse embryonic stem cells to infarcted sheep myocardium: a preclinical study by Ménard, Claudine, Hagège, Albert A, Agbulut, Onnik, Barro, Marietta, Morichetti, Miguel Cortes, Brasselet, Camille, Bel, Alain, Messas, Emmanuel, Bissery, Alvine, Bruneval, Patrick, Desnos, Michel, Pucéat, Michel, Menasché, Philippe

“…Heart failure develops after myocardial infarction and is a major cause of morbidity and mortality. The ability to direct differentiation of embryonic stem…”
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Myoblast transplantation for heart failure by Menasché, Philippe, Hagège, Albert A, Scorsin, Marcio, Pouzet, Bruno, Desnos, Michel, Duboc, Denis, Schwartz, Ketty, Vilquin, Jean-Thomas, Marolleau, Jean-Pierre

“…Intramyocardial skeletal muscle transplantation has been shown experimentally to improve heart function after infarction. We report success with this procedure…”
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Differentiation In Vivo of Cardiac Committed Human Embryonic Stem Cells in Postmyocardial Infarcted Rats by Tomescot, André, Leschik, Julia, Bellamy, Valérie, Dubois, Gilbert, Messas, Emmanuel, Bruneval, Patrick, Desnos, Michel, Hagège, Albert A., Amit, Michal, Itskovitz, Joseph, Menasché, Philippe, Pucéat, Michel

“…Human embryonic stem (HES) cells can give rise to cardiomyocytes in vitro. However, whether undifferentiated HES cells also feature a myocardial regenerative…”
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Screening patients with hypertrophic cardiomyopathy for Fabry disease using a filter-paper test: the FOCUS study by Hagège, Albert A, Caudron, Eric, Damy, Thibaud, Roudaut, Raymond, Millaire, Alain, Etchecopar-Chevreuil, Caroline, Tran, Thi-Chien, Jabbour, Firas, Boucly, Catherine, Prognon, Patrice, Charron, Philippe, Germain, Dominique P

“…Patients with Fabry disease (FD) show left ventricular hypertrophy (LVH) mimicking hypertrophic cardiomyopathy (HCM) of sarcomeric origin and might benefit, if…”
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Does the Flow Know? Mitral Regurgitant Jet Direction and Need for Valve Repair in Hypertrophic Obstructive Cardiomyopathy by Schwammenthal, Ehud, Hagège, Albert A., Levine, Robert A.

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Epicardial adipose stem cell sheets results in greater post-infarction survival than intramyocardial injections by Hamdi, Hadhami, Planat-Benard, Valérie, Bel, Alain, Puymirat, Etienne, Geha, Raghed, Pidial, Laetitia, Nematalla, Hany, Bellamy, Valérie, Bouaziz, Philippe, Peyrard, Séverine, Casteilla, Louis, Bruneval, Patrick, Hagège, Albert A., Agbulut, Onnik, Menasché, Philippe

“…Aims Intramyocardial injections of cells can damage tissue and enhance dissociation-induced cell death. We assessed whether epicardial delivery of cell sheets…”
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Viability and differentiation of autologous skeletal myoblast grafts in ischaemic cardiomyopathy by Hagège, Albert A, Carrion, Claire, Menasché, Philippe, Vilquin, Jean-Thomas, Duboc, Denis, Marolleau, Jean-Pierre, Desnos, Michel, Bruneval, Patrick

“…Autologous skeletal myoblast transplantation might improve postinfarction ventricular function, but graft viability and differentiation (ie, proof of concept)…”
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Exercise Capacity in Patients With Obstructive Hypertrophic Cardiomyopathy: SEQUOIA-HCM Baseline Characteristics and Study Design by Coats, Caroline J, Maron, Martin S, Abraham, Theodore P, Olivotto, Iacopo, Lee, Matthew M Y, Arad, Michael, Cardim, Nuno, Ma, Chang-Sheng, Choudhury, Lubna, Düngen, Hans-Dirk, Garcia-Pavia, Pablo, Hagège, Albert A, Lewis, Gregory D, Michels, Michelle, Oreziak, Artur, Owens, Anjali T, Tfelt-Hansen, Jacob, Veselka, Josef, Watkins, Hugh C, Heitner, Stephen B, Jacoby, Daniel L, Kupfer, Stuart, Malik, Fady I, Meng, Lisa, Wohltman, Amy, Masri, Ahmad

“…Patients with obstructive hypertrophic cardiomyopathy (oHCM) have increased risk of arrhythmia, stroke, heart failure, and sudden death. Contemporary…”
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Characterization of the paracrine effects of human skeletal myoblasts transplanted in infarcted myocardium by Perez-Ilzarbe, Maitane, Agbulut, Onnik, Pelacho, Beatriz, Ciorba, Cristina, Jose-Eneriz, Edurne San, Desnos, Michel, Hagège, Albert A., Aranda, Pablo, Andreu, Enrique J., Menasché, Philippe, Prósper, Felipe

“…Abstract Background: The discrepancy between the functional improvements yielded experimentally by skeletal myoblasts (SM) transplanted in infarcted myocardium…”
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Transplantation of autologous fresh bone marrow into infarcted myocardium: A word of caution by BEL, Alain, MESSAS, Emmanuel, AGBULUT, Onnik, RICHARD, Patrice, SAMUEL, Jane-Lyse, BRUNEVAL, Patrick, HAGEGE, Albert A, MENASCHE

“…As the benefits of extemporaneous transplantation (Tx) of fresh (unfractionated) autologous bone marrow (BM) have been primarily studied in the setting of…”
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