Search Results - "HAGEGE, A"
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Mapping Myocardial Fiber Orientation Using Echocardiography-Based Shear Wave Imaging
Published in IEEE transactions on medical imaging (01-03-2012)“…The assessment of disrupted myocardial fiber arrangement may help to understand and diagnose hypertrophic or ischemic cardiomyopathy. We hereby proposed and…”
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X-chromosome inactivation in female patients with Fabry disease
Published in Clinical genetics (01-01-2016)“…Fabry disease (FD) is an X‐linked genetic disorder caused by the deficient activity of lysosomal α‐galactosidase (α‐Gal). While males are usually severely…”
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The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) Trial : First Randomized Placebo-Controlled Study of Myoblast Transplantation
Published in Circulation (New York, N.Y.) (04-03-2008)“…Phase I clinical studies have demonstrated the feasibility of implanting autologous skeletal myoblasts in postinfarction scars. However, they have failed to…”
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Prevalence and clinical phenotype of hereditary transthyretin amyloid cardiomyopathy in patients with increased left ventricular wall thickness
Published in European heart journal (14-06-2016)“…Increased left ventricular wall thickness (LVWT) is a common finding in cardiology. It is not known how often hereditary transthyretin-related familial amyloid…”
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Mitral valve disease—morphology and mechanisms
Published in Nature reviews cardiology (01-12-2015)“…Key Points Mitral valve disease is a major cause of heart failure and mortality Even in adult life, the mitral valve is a dynamic structure and therapeutically…”
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Effect of Losartan on Mitral Valve Changes After Myocardial Infarction
Published in Journal of the American College of Cardiology (05-09-2017)“…After myocardial infarction (MI), mitral valve (MV) tethering stimulates adaptive leaflet growth, but counterproductive leaflet thickening and fibrosis augment…”
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Skeletal myoblast transplantation in ischemic heart failure : Long-term follow-up of the first phase I cohort of patients
Published in Circulation (New York, N.Y.) (04-07-2006)“…Skeletal myoblast (SM) transplantation (Tx) in a post-myocardial infarction (MI) scar experimentally improves left ventricular (LV) ejection fraction (EF)…”
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Aficamten for Symptomatic Obstructive Hypertrophic Cardiomyopathy
Published in The New England journal of medicine (30-05-2024)“…Among patients with symptomatic obstructive hypertrophic cardiomyopathy, treatment with aficamten led to a greater increase in peak oxygen consumption than…”
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Composite Cell Sheets A Further Step Toward Safe and Effective Myocardial Regeneration by Cardiac Progenitors Derived From Embryonic Stem Cells
Published in Circulation (New York, N.Y.) (14-09-2010)“…The safety and efficacy of myocardial regeneration using embryonic stem cells are limited by the risk of teratoma and the high rate of cell death. To address…”
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Transplantation of cardiac-committed mouse embryonic stem cells to infarcted sheep myocardium: a preclinical study
Published in The Lancet (British edition) (17-09-2005)“…Heart failure develops after myocardial infarction and is a major cause of morbidity and mortality. The ability to direct differentiation of embryonic stem…”
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Myoblast transplantation for heart failure
Published in The Lancet (British edition) (27-01-2001)“…Intramyocardial skeletal muscle transplantation has been shown experimentally to improve heart function after infarction. We report success with this procedure…”
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Differentiation In Vivo of Cardiac Committed Human Embryonic Stem Cells in Postmyocardial Infarcted Rats
Published in Stem cells (Dayton, Ohio) (01-09-2007)“…Human embryonic stem (HES) cells can give rise to cardiomyocytes in vitro. However, whether undifferentiated HES cells also feature a myocardial regenerative…”
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Screening patients with hypertrophic cardiomyopathy for Fabry disease using a filter-paper test: the FOCUS study
Published in Heart (British Cardiac Society) (01-01-2011)“…Patients with Fabry disease (FD) show left ventricular hypertrophy (LVH) mimicking hypertrophic cardiomyopathy (HCM) of sarcomeric origin and might benefit, if…”
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Epicardial adipose stem cell sheets results in greater post-infarction survival than intramyocardial injections
Published in Cardiovascular research (01-08-2011)“…Aims Intramyocardial injections of cells can damage tissue and enhance dissociation-induced cell death. We assessed whether epicardial delivery of cell sheets…”
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Viability and differentiation of autologous skeletal myoblast grafts in ischaemic cardiomyopathy
Published in The Lancet (British edition) (08-02-2003)“…Autologous skeletal myoblast transplantation might improve postinfarction ventricular function, but graft viability and differentiation (ie, proof of concept)…”
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Exercise Capacity in Patients With Obstructive Hypertrophic Cardiomyopathy: SEQUOIA-HCM Baseline Characteristics and Study Design
Published in JACC. Heart failure (01-01-2024)“…Patients with obstructive hypertrophic cardiomyopathy (oHCM) have increased risk of arrhythmia, stroke, heart failure, and sudden death. Contemporary…”
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Characterization of the paracrine effects of human skeletal myoblasts transplanted in infarcted myocardium
Published in European journal of heart failure (01-11-2008)“…Abstract Background: The discrepancy between the functional improvements yielded experimentally by skeletal myoblasts (SM) transplanted in infarcted myocardium…”
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Transplantation of autologous fresh bone marrow into infarcted myocardium: A word of caution
Published in Circulation (New York, N.Y.) (09-09-2003)“…As the benefits of extemporaneous transplantation (Tx) of fresh (unfractionated) autologous bone marrow (BM) have been primarily studied in the setting of…”
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