Search Results - "HAFNER, Roderick P."

Fel d 1–derived peptide antigen desensitization shows a persistent treatment effect 1 year after the start of dosing: A randomized, placebo-controlled study by Patel, Deepen, MD, Couroux, Peter, MD, Hickey, Pascal, PhD, Salapatek, Anne Marie, PhD, Laidler, Paul, PhD, Larché, Mark, PhD, Hafner, Roderick P., PhD

“…Background Allergic rhinoconjunctivitis is an increasingly common source of morbidity, with sensitivity to cats accounting for 10% to 15% of disease burden…”
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Treatment with grass allergen peptides improves symptoms of grass pollen–induced allergic rhinoconjunctivitis by Ellis, Anne K., MD, MSc, FRCPC, Frankish, Charles W., MD, FRCPC, O'Hehir, Robyn E., FRACP, PhD, Armstrong, Kristen, MSc, PMP, Steacy, Lisa, BSc, Larché, Mark, PhD, Hafner, Roderick P., PhD

“…Background Synthetic peptide immunoregulatory epitopes are a new class of immunotherapy to treat allergic rhinoconjunctivitis (ARC). Grass allergen peptides,…”
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Development and preliminary clinical evaluation of a peptide immunotherapy vaccine for cat allergy by Worm, Margitta, MD, Lee, Hae-Hyuk, MD, Kleine-Tebbe, Jörg, MD, Hafner, Roderick P., PhD, Laidler, Paul, PhD, Healey, David, MSc, Buhot, Cecile, PhD, Verhoef, Adrienne, PhD, Maillère, Bernard, PhD, Kay, A. Barry, MD, PhD, Larché, Mark, PhD

“…Background Allergic sensitization to cat allergens is common and represents a major risk factor for asthma. Specific immunotherapy (SIT) is effective but…”
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Persistence of the clinical effect of grass allergen peptide immunotherapy after the second and third grass pollen seasons by Ellis, Anne K., Frankish, Charles W., Armstrong, Kristen, Steacy, Lisa, Tenn, Mark W., Pawsey, Stephen, Hafner, Roderick P.

“…Grass allergen peptides are in development for the treatment of grass pollen–induced allergic rhinoconjunctivitis. A previous randomized, placebo-controlled…”
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Analysis of the control of respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the ‘top‐down’ approach of metabolic control theory by HAFNER, Roderick P., BROWN, Guy C., BRAND, Martin D.

“…The rate of respiration of isolated mitochondria was set at different values by addition of either oligomycin or an ADP‐regenerating system (glucose and…”
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Fel d 1aderived peptide antigen desensitization shows a persistent treatment effect 1 year after the start of dosing: AANBrandomized, placebo-controlled study by Patel, Deepen, Couroux, Peter, Hickey, Pascal, Salapatek, Anne Marie, Laidler, Paul, Larche, Mark, Hafner, Roderick P

“…Background: Allergic rhinoconjunctivitis is an increasingly common source of morbidity, with sensitivity to cats accounting for 10% to 15% of disease burden…”
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A ‘top‐down’ approach to the determination of control coefficients in metabolic control theory by BROWN, Guy C., HAFNER, Roderick P., BRAND, Martin D.

“…A new approach to the determination of flux and concentration control coefficients in metabolic pathways is outlined. Linear pathways are conceptually divided…”
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Hypothyroidism in rats decreases mitochondrial inner membrane cation permeability by Hafner, Roderick P., Leake, Michael J., Brand, Martin D.

“…We investigated the cation permeability of liver mitochondria isolated from hypothyroid or euthyroid rats by measuring the rate of swelling of respiring…”
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Thyroid hormone uptake into the cell and its subsequent localisation to the mitochondria by Hafner, Roderick P.

“…The nature of thyroid hormone uptake into the cell and the possible involvement of the serum carrier proteins and receptor-mediated endocytosis in this process…”
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The mechanism of the increase in mitochondrial proton permeability induced by thyroid hormones by BRAND, Martin D., STEVERDING, Dietmar, KADENBACH, Bernhard, STEVENSON, Patricia M., HAFNER, Roderick P.

“…Three possible mechanisms by which different levels of thyroid hormones in rats might cause the observed sevenfold change in the apparent proton permeability…”
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Altered relationship between protonmotive force and respiration rate in non‐phosphorylating liver mitochondria isolated from rats of different thyroid hormone status by HAFNER, Roderick P., NOBES, Catherine D., McGOWN, Anne D., BRAND, Martin D.

“…We have determined the relationship between rate of respiration and protonmotive force in oligomycininhibited liver mitochondria isolated from euthyroid,…”
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Stimulation of the electron transport chain in mitochondria isolated from rats treated with mannoheptulose or glucagon by Brand, M D, D'Alessandri, L, Reis, H M, Hafner, R P

“…We investigated the kinetics of the mitochondrial respiratory chain, proton leak, and phosphorylating subsystems of liver mitochondria from…”
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