Search Results - "HAFFTY, BRUCE"

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    VCAM-1 Promotes Osteolytic Expansion of Indolent Bone Micrometastasis of Breast Cancer by Engaging α4β1-Positive Osteoclast Progenitors by Lu, Xin, Mu, Euphemia, Wei, Yong, Riethdorf, Sabine, Yang, Qifeng, Yuan, Min, Yan, Jun, Hua, Yuling, Tiede, Benjamin J., Lu, Xuemin, Haffty, Bruce G., Pantel, Klaus, Massagué, Joan, Kang, Yibin

    Published in Cancer cell (01-12-2011)
    “…Breast cancer patients often develop locoregional or distant recurrence years after mastectomy. Understanding the mechanism of metastatic recurrence after…”
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    Journal Article
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    Radiation field design in the ACOSOG Z0011 (Alliance) Trial by Jagsi, Reshma, Chadha, Manjeet, Moni, Janaki, Ballman, Karla, Laurie, Fran, Buchholz, Thomas A, Giuliano, Armando, Haffty, Bruce G

    Published in Journal of clinical oncology (10-11-2014)
    “…ACOSOG Z0011 established that axillary lymph node dissection (ALND) is unnecessary in patients with breast cancer with one to two positive sentinel lymph nodes…”
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    Journal Article
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    Radiation-induced heart disease: pathologic abnormalities and putative mechanisms by Taunk, Neil K, Haffty, Bruce G, Kostis, John B, Goyal, Sharad

    Published in Frontiers in oncology (18-02-2015)
    “…Breast cancer is a common diagnosis in women. Breast radiation has become critical in managing patients who receive breast conserving surgery, or have certain…”
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    Journal Article
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    Radiation therapy for triple-negative breast cancer: from molecular insights to clinical perspectives by Kim, Jongmyung, Fahmy, Veronia, Haffty, Bruce G

    Published in Expert review of anticancer therapy (03-05-2024)
    “…Triple-negative breast cancer (TNBC) lacks three common receptors, making traditional treatments less effective. This review highlights the importance of…”
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    Journal Article
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    Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression by Liu, Juan, Zhang, Cen, Zhao, Yuhan, Yue, Xuetian, Wu, Hao, Huang, Shan, Chen, James, Tomsky, Kyle, Xie, Haiyang, Khella, Christen A., Gatza, Michael L., Xia, Dajing, Gao, Jimin, White, Eileen, Haffty, Bruce G., Hu, Wenwei, Feng, Zhaohui

    Published in Nature communications (28-11-2017)
    “…Mutations in E3 ubiquitin ligase Parkin have been linked to familial Parkinson’s disease. Accumulating evidence suggests that Parkin is a tumor suppressor, but…”
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    Journal Article
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    VCAM-1 Promotes Osteolytic Expansion of Indolent Bone Micrometastasis of Breast Cancer by Engaging alpha 4 beta 1-Positive Osteoclast Progenitors by Lu, Xin, Mu, Euphemia, Wei, Yong, Riethdorf, Sabine, Yang, Qifeng, Yuan, Min, Yan, Jun, Hua, Yuling, Tiede, Benjamin J, Lu, Xuemin, Haffty, Bruce G, Pantel, Klaus, Massague, Joan, Kang, Yibin

    Published in Cancer cell (13-12-2011)
    “…Breast cancer patients often develop locoregional or distant recurrence years after mastectomy. Understanding the mechanism of metastatic recurrence after…”
    Get full text
    Journal Article
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    Parkin ubiquitinates phosphoglycerate dehydrogenase to suppress serine synthesis and tumor progression by Liu, Juan, Zhang, Cen, Wu, Hao, Sun, Xiao-Xin, Li, Yanchen, Huang, Shan, Yue, Xuetian, Lu, Shou-En, Shen, Zhiyuan, Su, Xiaoyang, White, Eileen, Haffty, Bruce G, Hu, Wenwei, Feng, Zhaohui

    Published in The Journal of clinical investigation (01-06-2020)
    “…Phosphoglycerate dehydrogenase (PHGDH), the first rate-limiting enzyme of serine synthesis, is frequently overexpressed in human cancer. PHGDH overexpression…”
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    Journal Article
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    Effect of Travel Distance and Time to Radiotherapy on Likelihood of Receiving Mastectomy by Goyal, Sharad, Chandwani, Sheenu, Haffty, Bruce G., Demissie, Kitaw

    Published in Annals of surgical oncology (01-04-2015)
    “…Background Breast-conserving surgery (BCS) followed by adjuvant radiation therapy (RT) is the standard of care for women with early-stage breast cancer as an…”
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    Cullin3-KLHL25 ubiquitin ligase targets ACLY for degradation to inhibit lipid synthesis and tumor progression by Zhang, Cen, Liu, Juan, Huang, Grace, Zhao, Yuhan, Yue, Xuetian, Wu, Hao, Li, Jun, Zhu, Junlan, Shen, Zhiyuan, Haffty, Bruce G, Hu, Wenwei, Feng, Zhaohui

    Published in Genes & development (01-09-2016)
    “…Increased lipid synthesis is a key characteristic of many cancers that is critical for cancer progression. ATP-citrate lyase (ACLY), a key enzyme for lipid…”
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    Journal Article
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