Search Results - "HAFFTY, BRUCE"
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VCAM-1 Promotes Osteolytic Expansion of Indolent Bone Micrometastasis of Breast Cancer by Engaging α4β1-Positive Osteoclast Progenitors
Published in Cancer cell (01-12-2011)“…Breast cancer patients often develop locoregional or distant recurrence years after mastectomy. Understanding the mechanism of metastatic recurrence after…”
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Supine or Prone Breast Radiation: Upsides and Downsides
Published in International journal of radiation oncology, biology, physics (01-07-2018)Get full text
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Challenges Faced by Medical Journals During the COVID-19 Pandemic
Published in Journal of clinical oncology (01-07-2020)Get full text
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Radiation field design in the ACOSOG Z0011 (Alliance) Trial
Published in Journal of clinical oncology (10-11-2014)“…ACOSOG Z0011 established that axillary lymph node dissection (ALND) is unnecessary in patients with breast cancer with one to two positive sentinel lymph nodes…”
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Radiation-induced heart disease: pathologic abnormalities and putative mechanisms
Published in Frontiers in oncology (18-02-2015)“…Breast cancer is a common diagnosis in women. Breast radiation has become critical in managing patients who receive breast conserving surgery, or have certain…”
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Radiation therapy for triple-negative breast cancer: from molecular insights to clinical perspectives
Published in Expert review of anticancer therapy (03-05-2024)“…Triple-negative breast cancer (TNBC) lacks three common receptors, making traditional treatments less effective. This review highlights the importance of…”
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Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression
Published in Nature communications (28-11-2017)“…Mutations in E3 ubiquitin ligase Parkin have been linked to familial Parkinson’s disease. Accumulating evidence suggests that Parkin is a tumor suppressor, but…”
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SREBP1, targeted by miR-18a-5p, modulates epithelial-mesenchymal transition in breast cancer via forming a co-repressor complex with Snail and HDAC1/2
Published in Cell death and differentiation (01-05-2019)“…The progression of localized breast cancer to distant metastasis results in a poor prognosis and a high mortality rate. In this study, the contributions of…”
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Invited commentary on ‘Carbon footprint of the RSNA annual meeting’
Published in European journal of radiology (01-04-2020)Get full text
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Post-mastectomy Radiation, All in
Published in International journal of radiation oncology, biology, physics (01-10-2018)Get full text
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2022 Manuscript Reviewers: A Note of Thanks
Published in Radiology (01-12-2022)Get full text
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Fractionation for Whole Breast Irradiation: An American Society for Radiation Oncology (ASTRO) Evidence-Based Guideline
Published in International journal of radiation oncology, biology, physics (01-09-2011)“…Purpose In patients with early-stage breast cancer treated with breast-conserving surgery, randomized trials have found little difference in local control and…”
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MTDH-SND1 Interaction Is Crucial for Expansion and Activity of Tumor-Initiating Cells in Diverse Oncogene- and Carcinogen-Induced Mammary Tumors
Published in Cancer cell (14-07-2014)“…The Metadherin gene (MTDH) is prevalently amplified in breast cancer and associated with poor prognosis; however, its functional contribution to tumorigenesis…”
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VCAM-1 Promotes Osteolytic Expansion of Indolent Bone Micrometastasis of Breast Cancer by Engaging alpha 4 beta 1-Positive Osteoclast Progenitors
Published in Cancer cell (13-12-2011)“…Breast cancer patients often develop locoregional or distant recurrence years after mastectomy. Understanding the mechanism of metastatic recurrence after…”
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Local Recurrence After Breast-Conserving Therapy in Patients With Multiple Ipsilateral Breast Cancer: Results From ACOSOG Z11102 (Alliance)
Published in Journal of clinical oncology (10-06-2023)“…Breast-conserving therapy (BCT) is the preferred treatment for unifocal breast cancer (BC). The oncologic safety of BCT for multiple ipsilateral breast cancer…”
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Parkin ubiquitinates phosphoglycerate dehydrogenase to suppress serine synthesis and tumor progression
Published in The Journal of clinical investigation (01-06-2020)“…Phosphoglycerate dehydrogenase (PHGDH), the first rate-limiting enzyme of serine synthesis, is frequently overexpressed in human cancer. PHGDH overexpression…”
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Effect of Travel Distance and Time to Radiotherapy on Likelihood of Receiving Mastectomy
Published in Annals of surgical oncology (01-04-2015)“…Background Breast-conserving surgery (BCS) followed by adjuvant radiation therapy (RT) is the standard of care for women with early-stage breast cancer as an…”
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Cullin3-KLHL25 ubiquitin ligase targets ACLY for degradation to inhibit lipid synthesis and tumor progression
Published in Genes & development (01-09-2016)“…Increased lipid synthesis is a key characteristic of many cancers that is critical for cancer progression. ATP-citrate lyase (ACLY), a key enzyme for lipid…”
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Excision and Reirradiation for Local Recurrence in Previously Treated Patient
Published in International journal of radiation oncology, biology, physics (01-11-2019)Get full text
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