Search Results - "HAEDERSDAL, Merete"

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    Translational medicine in the field of ablative fractional laser (AFXL)-assisted drug delivery: A critical review from basics to current clinical status by Haedersdal, Merete, MD, PhD, DMSc, Erlendsson, Andrés M., MD, PhD, Paasch, Uwe, MD, PhD, Anderson, R. Rox, MD

    “…Background Ablative fractional lasers enhance uptake of topical therapeutics and the concept of fractional laser-assisted drug delivery has now been taken into…”
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    Journal Article
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    Vascular feature identification in actinic keratosis grades I-III using dynamic optical coherence tomography with automated, quantitative analysis by Fredman, Gabriella, Wiegell, Stine R., Haedersdal, Merete, Untracht, Gavrielle R.

    Published in Archives of Dermatological Research (15-06-2024)
    “…Clinical grading of actinic keratosis (AK) is based on skin surface features, while subclinical alterations are not taken into consideration. Dynamic optical…”
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    Journal Article
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    Criteria for site selection in industry-sponsored clinical trials: a survey among decision-makers in biopharmaceutical companies and clinical research organizations by Dombernowsky, Tilde, Haedersdal, Merete, Lassen, Ulrik, Thomsen, Simon Francis

    “…Knowledge of what the pharmaceutical industry emphasizes when assessing trial sites during site selection is sparse. A better understanding of this issue can…”
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    Journal Article
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    Vascular Characteristics of Treatment-resistant and -responsive Actinic Keratosis Identified with Dynamic Optical Coherence Tomography by Fredman, Gabriella, Haedersdal, Merete, Philipsen, Peter A., Andersen, Flemming, Bjerring, Peter, Wiegell, Stine R., Untracht, Gavrielle

    Published in Acta dermato-venereologica (25-11-2024)
    “…Treatment-resistant actinic keratosis (AK) is of concern in clinical practice, often requiring retreatment. Microvascular assessments might help differentiate…”
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    Prebiotic and panthenol-containing dermocosmetic improves tolerance from artificial daylight photodynamic therapy: A randomized controlled trial in patients with actinic keratosis by Fredman, Gabriella, Jacobsen, Kevin, Philipsen, Peter A, Wiegell, Stine R, Haedersdal, Merete

    Published in Photodiagnosis and photodynamic therapy (01-12-2024)
    “…•Treatment of actinic keratosis with dPDT is associated with local skin reactions (LSR).•Application of a dermocosmetic cream (DC) might improve post-dPDT…”
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    Cutaneous squamous cell carcinoma characterized by MALDI mass spectrometry imaging in combination with machine learning by Brorsen, Lauritz F., McKenzie, James S., Tullin, Mette F., Bendtsen, Katja M. S., Pinto, Fernanda E., Jensen, Henrik E., Haedersdal, Merete, Takats, Zoltan, Janfelt, Christian, Lerche, Catharina M.

    Published in Scientific reports (15-05-2024)
    “…Cutaneous squamous cell carcinoma (SCC) is an increasingly prevalent global health concern. Current diagnostic and surgical methods are reliable, but they…”
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    Journal Article
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    Risk of Anogenital Warts in Renal Transplant Recipients Compared with Immunocompetent Controls: A Cross-sectional Clinical Study by Larsen, H, Thomsen, L, Hædersdal, M, Lok, T, Hansen, J, Sørensen, S, Kjær, S

    Published in Acta dermato-venereologica (01-07-2021)
    “…Renal transplant recipients have increased risk of human papilloma virus-related anogenital (pre)cancers. Less is known about their risk of anogenital warts…”
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    Off-Label 9-Valent Human Papillomavirus Vaccination for Actinic Keratosis: A Case Series by Wenande, Emily, Bech-Thomsen, Niels, Togsverd-Bo, Katrine, Haedersdal, Merete

    Published in Case reports in dermatology (01-09-2021)
    “…Background: The suspected link between human papillomavirus (HPV) and the development of premalignant and malignant skin lesions remains inadequately examined…”
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    An Explorative Study on Calcium Electroporation for Low-risk Basal Cell Carcinoma by Wiegell, Stine R, Hendel, Kristoffer, Fuchs, Christine S K, Gehl, Julie, Vissing, Mille, Bro, Sara W, Troelsen, Jesper T, Jemec, Gregor B E, Haedersdal, Merete

    Published in Acta dermato-venereologica (07-05-2024)
    “…In electrochemotherapy, permeabilization of the cell membrane by electric pulses increases the anti-tumour effect of chemotherapeutics. In calcium…”
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    Optical Imaging Visualizes a Homogeneous and Horizontal Band-Like Biodistribution of Large- and Small-Size Hydrophilic Compounds Delivered by Ablative Fractional Laser by Christensen, Rikke Louise, Ortner, Vinzent Kevin, Haedersdal, Merete, Olesen, Uffe Høgh

    Published in Pharmaceutics (23-07-2022)
    “…The skin barrier generally limits the topical delivery of hydrophilic molecules. Ablative fractional laser (AFL) facilitates cutaneous drug uptake of smaller…”
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    Journal Article
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    Quantitative Mass Spectrometry Imaging of Bleomycin in Skin Using a Mimetic Tissue Model for Calibration by Traberg, Andreas, Pinto, Fernanda E, Hansen, Anders C N, Haedersdal, Merete, Lerche, Catharina M, Janfelt, Christian

    Published in Pharmaceuticals (Basel, Switzerland) (19-12-2022)
    “…The aim of Quantitative mass spectrometry imaging (Q-MSI) is to provide distribution analysis and quantitation from one single mass-spectrometry-based…”
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    Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging by Hendel, Kristoffer K., Bagger, Charlotte, Olesen, Uffe H., Janfelt, Christian, Hansen, Steen H., Haedersdal, Merete, Lerche, Catharina M.

    Published in Drug delivery (01-01-2019)
    “…Bleomycin exhibits antiproliferative effects desirable for use in dermato-oncology but topical use is limited by its 1415 Da molar mass. Ablative fractional…”
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    Journal Article
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