Search Results - "HAASE, Ingo"

CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair by Willenborg, Sebastian, Lucas, Tina, van Loo, Geert, Knipper, Johanna A., Krieg, Thomas, Haase, Ingo, Brachvogel, Bent, Hammerschmidt, Matthias, Nagy, Andras, Ferrara, Napoleone, Pasparakis, Manolis, Eming, Sabine A.

“…Monocytes/macrophages are critical in orchestrating the tissue-repair response. However, the mechanisms that govern macrophage regenerative activities during…”
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Epidermal Rac1 regulates the DNA damage response and protects from UV-light-induced keratinocyte apoptosis and skin carcinogenesis by Deshmukh, Jayesh, Pofahl, Ruth, Haase, Ingo

“…Non-melanoma skin cancer (NMSC) is the most common type of cancer. Increased expression and activity of Rac1, a small Rho GTPase, has been shown previously in…”
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The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation by Bonnet, Marion C., Preukschat, Daniela, Welz, Patrick-Simon, van Loo, Geert, Ermolaeva, Maria A., Bloch, Wilhelm, Haase, Ingo, Pasparakis, Manolis

“…Epidermal keratinocytes provide an essential structural and immunological barrier forming the first line of defense against potentially pathogenic…”
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Tumor Necrosis Factor Receptor Signaling in Keratinocytes Triggers Interleukin-24-Dependent Psoriasis-like Skin Inflammation in Mice by Kumari, Snehlata, Bonnet, Marion C., Ulvmar, Maria H., Wolk, Kerstin, Karagianni, Niki, Witte, Ellen, Uthoff-Hachenberg, Claudia, Renauld, Jean-Christophe, Kollias, George, Toftgard, Rune, Sabat, Robert, Pasparakis, Manolis, Haase, Ingo

“…Psoriasis is a common chronic inflammatory skin disease with a prevalence of about 2% in the Caucasian population. Tumor necrosis factor (TNF) plays an…”
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Rac1 Is Crucial for Hair Follicle Integrity but Is Not Essential for Maintenance of the Epidermis by Chrostek, Anna, Wu, Xunwei, Quondamatteo, Fabio, Hu, Rong, Sanecka, Anna, Niemann, Catherin, Langbein, Lutz, Haase, Ingo, Brakebusch, Cord

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Impact of Rac1 and Cdc42 Signaling during Early Herpes Simplex Virus Type 1 Infection of Keratinocytes by PETERMANN, Philipp, HAASE, Ingo, KNEBEL-MÖRSDORF, Dagmar

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Signaling via β1 integrins and mitogen-activated protein kinase determines human epidermal stem cell fate in vitro by Zhu, Alan Jian, Haase, Ingo, Watt, Fiona M.

“…Human epidermal stem cells express higher levels of β1 integrins and are more adhesive than keratinocytes that are destined to differentiate. To investigate…”
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Normal epidermal differentiation but impaired skin-barrier formation upon keratinocyte-restricted IKK1 ablation by Pasparakis, Manolis, Gareus, Ralph, Huth, Marion, Breiden, Bernadette, Nenci, Arianna, Rösch, Nora, Haase, Ingo, Bloch, Wilhelm, Sandhoff, Konrad

“…The kinase IKK1 (also known as IKKα) was previously reported to regulate epidermal development and skeletal morphogenesis by acting in keratinocytes to induce…”
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Fibroblasts in Mechanically Stressed Collagen Lattices Assume a “Synthetic” Phenotype by Kessler, Daniela, Dethlefsen, Silke, Haase, Ingo, Plomann, Markus, Hirche, Frank, Krieg, Thomas, Eckes, Beate

“…Fibroblasts are subjected to changes of the mechanical force balance during physiological as well as pathological situations, such as wound healing,…”
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Tumor immune escape by the loss of homeostatic chemokine expression by Pivarcsi, Andor, Müller, Anja, Hippe, Andreas, Rieker, Juliane, van Lierop, Anke, Steinhoff, Martin, Seeliger, Stephan, Kubitza, Robert, Pippirs, Ulrich, Meller, Stephan, Gerber, Peter A, Liersch, Ruediger, Buenemann, Erich, Sonkoly, Eniko, Wiesner, Ulrike, Hoffmann, Thomas K, Schneider, Leonid, Piekorz, Roland, Enderlein, Elaine, Reifenberger, Julia, Rohr, Ulrich-Peter, Haas, Rainer, Boukamp, Petra, Haase, Ingo, Nürnberg, Bernd, Ruzicka, Thomas, Zlotnik, Albert, Homey, Bernhard

“…The novel keratinocyte-specific chemokine CCL27 plays a critical role in the organization of skin-associated immune responses by regulating T cell homing under…”
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Impaired epidermal wound healing in vivo upon inhibition or deletion of Rac1 by Tscharntke, Michael, Pofahl, Ruth, Chrostek-Grashoff, Anna, Smyth, Neil, Niessen, Carien, Niemann, Catherin, Hartwig, Benedikt, Herzog, Volker, Klein, Helmut W, Krieg, Thomas, Brakebusch, Cord, Haase, Ingo

“…To address the functions of Rac1 in keratinocytes of the basal epidermal layer and in the outer root sheath of hair follicles, we generated transgenic mice…”
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Establishment of spontaneously immortalized keratinocyte lines from wild-type and mutant mice by Reichelt, Julia, Haase, Ingo

“…A considerable number of transgenic or knockout mice in which epidermal keratinocytes have been targeted die shortly after birth due to barrier defects. In…”
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Skin lesion development in a mouse model of incontinentia pigmenti is triggered by NEMO deficiency in epidermal keratinocytes and requires TNF signaling by Nenci, Arianna, Huth, Marion, Funteh, Alfred, Schmidt-Supprian, Marc, Bloch, Wilhelm, Metzger, Daniel, Chambon, Pierre, Rajewsky, Klaus, Krieg, Thomas, Haase, Ingo, Pasparakis, Manolis

“…NF-κB essential modulator (NEMO), the regulatory subunit of the IκB kinase, is essential for NF-κB activation. Mutations disrupting the X-linked NEMO gene…”
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A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis by Haase, I, Hobbs, R M, Romero, M R, Broad, S, Watt, F M

“…In normal epidermis, beta1 integrin expression is confined to the basal layer, whereas in hyperproliferative epidermis, integrins are also expressed in the…”
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Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein by Hafner, Martin, Wenk, Jutta, Nenci, Arianna, Pasparakis, Manolis, Scharffetter-Kochanek, Karin, Smyth, Neil, Peters, Thorsten, Kess, Daniel, Holtkötter, Olaf, Shephard, Pierre, Kudlow, Jeffrey E., Smola, Hans, Haase, Ingo, Schippers, Angela, Krieg, Thomas, Müller, Werner

“…Three mouse lines expressing Cre recombinase under the control of the human K14 promoter induced specific deletion of loxP flanked target sequences in the…”
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Accuracy of retrospective pain measurement in patients with chronic pain by Haase, Ingo

“…The use of pain scales that refer to a past time period is thereby based on the assumption that patients accurately remember their 'average', 'greatest' and…”
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Mechanisms regulating skin immunity and inflammation by Pasparakis, Manolis, Haase, Ingo, Nestle, Frank O.

“…Key Points Monocytes and macrophages are increasingly recognized as important effector cells in inflammatory skin reactions. Depending on the cytokine milieu,…”
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C3a and C5a stimulate chemotaxis of human mast cells by HARTMANN, K, HENZ, B. M, KRÜGER-KRASAGAKES, S, KÖHL, J, BURGER, R, GUHL, S, HAASE, I, LIPPERT, U, ZUBERBIER, T

“…The factors that control migration of mast cells to sites of inflammation and tissue repair remain largely undefined. Whereas several recent studies have…”
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Localized Inflammatory Skin Disease Following Inducible Ablation of I Kappa B Kinase 2 in Murine Epidermis by Stratis, Athanasios, Pasparakis, Manolis, Markur, Doreen, Knaup, Renate, Pofahl, Ruth, Metzger, Daniel, Chambon, Pierre, Krieg, Thomas, Haase, Ingo

“…Skin inflammation is a complex process that involves interactions between various cell types residing in different skin compartments. Using mice with…”
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Clinical Relevance of Changes in Pain Intensity in Patients with Specific Back Pain by Haase, Ingo, Kladny, Bernd

“…Pain intensity is frequently measured on the 11-point numerical pain rating scale (NRS-PI), ranging from 0 (no pain) to 10 points (worst imaginable pain)…”
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