Search Results - "HAACKE, E. Mark"
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Susceptibility-weighted Imaging: Technical Essentials and Clinical Neurologic Applications
Published in Radiology (01-04-2021)“…Susceptibility-weighted imaging (SWI) evolved from simple two-dimensional T2*-weighted sequences to three-dimensional sequences with improved spatial…”
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Quantitative susceptibility mapping: current status and future directions
Published in Magnetic resonance imaging (01-01-2015)“…Abstract Quantitative susceptibility mapping (QSM) is a new technique for quantifying magnetic susceptibility. It has already found various applications in…”
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STrategically Acquired Gradient Echo (STAGE) imaging, part I: Creating enhanced T1 contrast and standardized susceptibility weighted imaging and quantitative susceptibility mapping
Published in Magnetic resonance imaging (01-02-2018)“…To provide whole brain grey matter (GM) to white matter (WM) contrast enhanced T1W (T1WE) images, multi-echo quantitative susceptibility mapping (QSM), proton…”
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Grading of Gliomas by Using Monoexponential, Biexponential, and Stretched Exponential Diffusion-weighted MR Imaging and Diffusion Kurtosis MR Imaging
Published in Radiology (01-02-2016)“…To quantitatively compare the potential of various diffusion parameters obtained from monoexponential, biexponential, and stretched exponential…”
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Vascular mapping of the human hippocampus using Ferumoxytol-enhanced MRI
Published in NeuroImage (Orlando, Fla.) (15-04-2022)“…The hippocampus is a small but complex grey matter structure that plays an important role in spatial and episodic memory and can be affected by a wide range of…”
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Principles, techniques, and applications of T2-based MR imaging and its special applications
Published in Radiographics (01-09-2009)“…T2* relaxation refers to decay of transverse magnetization caused by a combination of spin-spin relaxation and magnetic field inhomogeneity. T2* relaxation is…”
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Cerebral microbleed detection using Susceptibility Weighted Imaging and deep learning
Published in NeuroImage (Orlando, Fla.) (01-09-2019)“…Detecting cerebral microbleeds (CMBs) is important in diagnosing a variety of diseases including dementia, stroke and traumatic brain injury. However, manual…”
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Final Results of the RHAPSODY Trial: A Multi‐Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A‐APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen Activator, Mechanical Thrombectomy or both in Moderate to Severe Acute Ischemic Stroke
Published in Annals of neurology (01-01-2019)“…Objective Agonism of protease‐activated receptor (PAR) 1 by activated protein C (APC) provides neuro‐ and vasculoprotection in experimental neuroinjury models…”
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Optimizing neuromelanin contrast in the substantia nigra and locus coeruleus using a magnetization transfer contrast prepared 3D gradient recalled echo sequence
Published in NeuroImage (Orlando, Fla.) (01-09-2020)“…Neuromelanin (NM) loss in the substantia nigra (SN) and locus coeruleus (LC) is being investigated as an imaging biomarker for Parkinson’s disease (PD) using…”
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Susceptibility‐weighted imaging: current status and future directions
Published in NMR in biomedicine (01-04-2017)“…Susceptibility‐weighted imaging (SWI) is a method that uses the intrinsic nature of local magnetic fields to enhance image contrast in order to improve the…”
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In vivo vascular mapping of the human hippocampus using MICRO imaging
Published in Veins and lymphatics (23-11-2022)“…BACKGROUND: There is an urgent need for better detection and understanding of vascular abnormalities at the micro-level, where critical vascular nourishment…”
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Imaging iron and neuromelanin simultaneously using a single 3D gradient echo magnetization transfer sequence: Combining neuromelanin, iron and the nigrosome-1 sign as complementary imaging biomarkers in early stage Parkinson's disease
Published in NeuroImage (Orlando, Fla.) (15-04-2021)“…Diagnosing early stage Parkinson's disease (PD) is still a clinical challenge. Previous studies using iron, neuromelanin (NM) or the Nigrosome-1 (N1) sign in…”
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Radiomic Features of the Nigrosome-1 Region of the Substantia Nigra: Using Quantitative Susceptibility Mapping to Assist the Diagnosis of Idiopathic Parkinson's Disease
Published in Frontiers in aging neuroscience (16-07-2019)“…The loss of nigrosome-1, which is also referred to as the swallow tail sign (STS) in T2 -weighted iron-sensitive magnetic resonance imaging (MRI), has recently…”
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Quantitative susceptibility mapping in the human fetus to measure blood oxygenation in the superior sagittal sinus
Published in European radiology (01-04-2019)“…Objectives To present the feasibility of performing quantitative susceptibility mapping (QSM) in the human fetus to evaluate the oxygenation ( S v O 2 ) of…”
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Measuring iron in the brain using quantitative susceptibility mapping and X-ray fluorescence imaging
Published in NeuroImage (Orlando, Fla.) (01-09-2013)“…Measuring iron content in the brain has important implications for a number of neurodegenerative diseases. Quantitative susceptibility mapping (QSM), derived…”
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Plaque characteristics of middle cerebral artery assessed using strategically acquired gradient echo (STAGE) and vessel wall MR contribute to misery downstream perfusion in patients with intracranial atherosclerosis
Published in European radiology (2021)“…Objectives To assess plaque vulnerability of the middle cerebral artery (MCA) using strategically acquired gradient echo (STAGE) versus high-resolution vessel…”
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Fetal brain tissue characterization at 1.5 T using STrategically Acquired Gradient Echo (STAGE) imaging
Published in European radiology (01-08-2021)“…Objectives To estimate human fetal brain MRI tissue properties including apparent T 1 (T 1app ) and apparent proton density (PD app ) by using a rapid…”
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In Vivo visualization of white matter fiber tracts in the brainstem using low flip angle double echo 3D gradient echo imaging at 3T
Published in NeuroImage (Orlando, Fla.) (15-10-2024)“…•A new clinically feasible double echo spin density weighted gradient echo sequence was developed for imaging WM fiber tracts in the brainstem in vivo at…”
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Subvoxel vascular imaging of the midbrain using USPIO-Enhanced MRI
Published in NeuroImage (Orlando, Fla.) (15-10-2020)“…There is an urgent need for better detection and understanding of vascular abnormalities at the micro-level, where critical vascular nourishment and cellular…”
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In vivo mapping of hippocampal venous vasculature and oxygenation using susceptibility imaging at 7T
Published in NeuroImage (Orlando, Fla.) (01-05-2024)“…•Venous arch structures of hippocampus are shown using high resolution SWI at 7T.•Hippocampal venous density is calculated to characterize hippocampal oxygen…”
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