Search Results - "H.-R. Brenner"
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Synapses Form in Skeletal Muscles Lacking Neuregulin Receptors
Published in Science (American Association for the Advancement of Science) (24-06-2005)“…The formation of the neuromuscular junction (NMJ) is directed by reciprocal interactions between motor neurons and muscle fibers. Neuregulin (NRG) and Agrin…”
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Advances in neurobiology of the neuromuscular junction. Implications for the anesthesiologist
Published in Anesthesiology (Philadelphia) (2002)Get full text
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Neural Factors Regulate AChR Subunit mRNAs at Rat Neuromuscular Synapses
Published in The Journal of cell biology (01-07-1991)“…To elucidate the nature of signals that control the level and spatial distribution of mRNAs encoding acetylcholine receptor (AChR), α-, β-, γ-, δ- and…”
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4
Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice
Published in Cell (20-10-1995)“…Regulation of neurite outgrowth and structural plasticity may involve the expression of intrinsic determinants controlling growth competence. We have tested…”
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Induction by Agrin of Ectopic and Functional Postsynaptic-Like Membrane in Innervated Muscle
Published in Proceedings of the National Academy of Sciences - PNAS (18-03-1997)“…Two factors secreted from the nerve terminal, agrin and neuregulin, have been postulated to induce localization of the acetylcholine receptors (AChRs) to the…”
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Myogenin and MyoD Join a Family of Skeletal Muscle Genes Regulated by Electrical Activity
Published in Proceedings of the National Academy of Sciences - PNAS (15-02-1991)“…Myogenin and MyoD are proteins that bind to the regulatory regions of a battery of skeletal muscle genes and can activate their transcription during muscle…”
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Imprinting of acetylcholine receptor messenger RNA accumulation in mammalian neuromuscular synapses
Published in Nature (London) (05-04-1990)“…IN mammalian muscle, the subunit composition of the nicotinic acetylcholine receptor (AChR) and the distribution of AChRs along the fibre are developmentally…”
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Acetylcholine Receptor ε -subunit Deletion Causes Muscle Weakness and Atrophy in Juvenile and Adult Mice
Published in Proceedings of the National Academy of Sciences - PNAS (12-11-1996)“…In mammalian muscle a postnatal switch in functional properties of neuromuscular transmission occurs when miniature end plate currents become shorter and the…”
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Substrate-Bound Agrin Induces Expression of Acetylcholine Receptor ε -Subunit Gene in Cultured Mammalian Muscle Cells
Published in Proceedings of the National Academy of Sciences - PNAS (11-06-1996)“…Expression of the ε -subunit gene of the acetylcholine receptor (AChR) by myonuclei located at the neuromuscular junction is precisely regulated during…”
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Synapse-specific expression of acetylcholine receptor genes and their products at original synaptic sites in rat soleus muscle fibres regenerating in the absence of innervation
Published in Development (Cambridge) (01-09-1992)“…To test the hypothesis that synaptic basal lamina can induce synapse-specific expression of acetylcholine receptor (AChR) genes, we examined the levels mRNA…”
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Neuregulin signaling is dispensable for NMDA- and GABA(A)-receptor expression in the cerebellum in vivo
Published in The Journal of neuroscience (25-02-2009)“…Neuregulin-1s (NRG-1s) are a family of growth and differentiation factors with multiple roles in the development and function in different organs including the…”
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12
Normal Development of Nerve--Muscle Synapses in Mice Lacking the Prion Protein Gene
Published in Proceedings of the Royal Society. B, Biological sciences (23-11-1992)“…The expression of acetylcholine receptors (AChR) at neuromuscular synapses in skeletal muscle is regulated by innervation. Recent evidence suggests that the…”
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13
Calcium influx and protein phosphorylation mediate the metabolic stabilization of synaptic acetylcholine receptors in muscle
Published in The Journal of neuroscience (01-03-1993)“…During neuromuscular synapse development, the degradation rate of ACh receptors (AChRs) accumulated in the synaptic portion of the muscle membrane is…”
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Metabolic Stabilization of Acetylcholine Receptors in Vertebrate Neuromuscular Junction by Muscle Activity
Published in The Journal of cell biology (01-08-1990)“…The effects of muscle activity on the growth of synaptic acetylcholine receptor (AChR) accumulations and on the metabolic AChR stability were investigated in…”
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15
Neuregulin Signaling Is Dispensable for NMDA- and GABAA-Receptor Expression in the Cerebellum In Vivo
Published in The Journal of neuroscience (25-02-2009)“…Neuregulin-1s (NRG-1s) are a family of growth and differentiation factors with multiple roles in the development and function in different organs including the…”
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16
On the effect of muscle activity on the end-plate membrane in denervated mouse muscle
Published in The Journal of physiology (01-03-1989)“…1. Mouse soleus muscles were denervated and some of them were chronically stimulated. Sixteen to twenty-one days later, the number of junctional acetylcholine…”
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Involvement of extracellular matrix in acetylcholine receptor ϵ-subunit gene expression at the rat neuromuscular junction
Published in Neuroscience letters (23-06-1995)“…During neuromuscular development, the nerve induces the expression of acetylcholine receptor (AChR) ϵ-subunit gene selectively in synaptic myonuclei. Here we…”
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Change in synaptic channel gating during neuromuscular development
Published in Nature (London) (23-11-1978)Get full text
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A Novel Pathway for MuSK to Induce Key Genes in neuromuscular Synapse Formation
Published in The Journal of cell biology (26-05-2003)“…At the developing neuromuscular junction the Agrin receptor MuSK is the central organizer of subsynaptic differentiation induced by Agrin from the nerve. The…”
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Rapid drug application resolves two types of nicotinic receptors on rat sympathetic ganglion cells
Published in Pflügers Archiv (01-05-1997)“…The properties of nicotinic acetylcholine receptors (AChRs) on cultured rat superior cervical ganglion (SCG) neurons were analysed. AChR agonists…”
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