Search Results - "H.-G. Knaus"

Cerebellar Ataxia and Purkinje Cell Dysfunction Caused by Ca2+-Activated K+Channel Deficiency by Sausbier, M., Hu, H., Arntz, C., Feil, S., Kamm, S., Adelsberger, H., Sausbier, U., Sailer, C. A., Feil, R., Hofmann, F., Korth, M., Shipston, M. J., H.-G. Knaus, Wolfer, D. P., Pedroarena, C. M., Storm, J. F., Ruth, P., Andersen, Per O.

“…Malfunctions of potassium channels are increasingly implicated as causes of neurological disorders. However, the functional roles of the large-conductance…”
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An Endoplasmic Reticulum Trafficking Signal Prevents Surface Expression of a Voltage- and Ca2+-Activated K+ Channel Splice Variant by Zarei, M. M., Eghbali, M., Alioua, A., Song, M., H.-G. Knaus, Stefani, E., Toro, L., MacLennan, David H.

“…Protein delivery to restricted plasma membrane domains is exquisitely regulated at different stages of the cell trafficking machinery. Traffic control involves…”
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Endocytic trafficking signals in KCNMB2 regulate surface expression of a large conductance voltage and Ca2+ -activated K+ channel by Zarei, M.M, Song, M, Wilson, R.J, Cox, N, Colom, L.V, Knaus, H.-G, Stefani, E, Toro, L

“…Abstract Large conductance voltage and calcium-activated K+ channels play critical roles in neuronal excitability and vascular tone. Previously, we showed that…”
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rKv1.2 overexpression in the central medial thalamic area decreases caffeine‐induced arousal by Cazzin, C., Piccoli, L., Massagrande, M., Garbati, N., Michielin, F., Knaus, H.‐G., Ring, C. J. A., Morrison, A. D., Merlo‐Pich, E., Rovo, Z., Astori, S., Lüthi, A., Corti, C., Corsi, M.

“…The voltage‐gated potassium channel Kv1.2 belongs to the shaker‐related family and has recently been implicated in the control of sleep profile on the basis of…”
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Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons by Dolga, A M, de Andrade, A, Meissner, L, Knaus, H-G, Höllerhage, M, Christophersen, P, Zischka, H, Plesnila, N, Höglinger, G U, Culmsee, C

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Subunit composition of the high conductance calcium-activated potassium channel from smooth muscle, a representative of the mSlo and slowpoke family of potassium channels by KNAUS, H.-G, GARCIA-CALVO, M, KACZOROWSKI, G. J, GARCIA, M. L

“…High conductance Ca(2+)-activated K+ (maxi-K) channels from bovine tracheal and aortic smooth muscle membranes have been purified employing monoiodotyrosine…”
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High affinity interaction of mibefradil with voltage‐gated calcium and sodium channels by Eller, Philipp, Berjukov, Stanislav, Wanner, Siegmund, Huber, Irene, Hering, Steffen, Knaus, Hans‐Günther, Toth, Geza, Kimball, S David, Striessnig, Jörg

“…Mibefradil is a novel Ca2+ antagonist which blocks both high‐voltage activated and low voltage‐activated Ca2+ channels. Although L‐type Ca2+ channel block was…”
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Purification and reconstitution of the high-conductance, calcium-activated potassium channel from tracheal smooth muscle by GARCIA-CALVO, M, KNAUS, H.-G, MCMANUS, O. B, GIANGIACOMO, K. M, KACZOROWSKI, G. J, GARCIA, M. L

“…The high-conductance Ca(2+)-activated K+ (maxi-K) channel from bovine tracheal smooth muscle was purified to apparent homogeneity by a combination of…”
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Distribution of high-conductance Ca(2+)-activated K+ channels in rat brain: targeting to axons and nerve terminals by Knaus, HG, Schwarzer, C, Koch, RO, Eberhart, A, Kaczorowski, GJ, Glossmann, H, Wunder, F, Pongs, O, Garcia, ML, Sperk, G

“…Tissue expression and distribution of the high-conductance Ca(2+)-activated K+ channel Slo was investigated in rat brain by immunocytochemistry, in situ…”
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Charybdotoxin and its effects on potassium channels by Garcia, M L, Knaus, H G, Munujos, P, Slaughter, R S, Kaczorowski, G J

“…Over the last few years, a considerable amount of information has been obtained regarding K+ channels. Different areas of research have contributed to…”
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Subunit composition of brain voltage-gated potassium channels determined by hongotoxin-1, novel peptide derived from Centruroides limbatus venom by Koschak, A, Bugianesi, R.M, Mitterdorfer, J, Kaczorowski, G.J, Garcia, M.L, Knaus, H.G

“…Five novel peptidyl inhibitors of Shaker-type (Kv1) K+ channels have been purified to homogeneity from venom of the scorpion Centruroides limbatus. The…”
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Increased Expression of Ca2+ -Sensitive K+ Channels in Aorta of Hypertensive Rats by Liu, Yanping, Pleyte, Kay, Knaus, Hans-Guenther, Rusch, Nancy J

“…Potassium efflux through Ca -sensitive K channels (KCa channels) is increased in arterial smooth muscle cells from hypertensive rats, but the molecular…”
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Increased Expression of Ca2+-Sensitive K+ Channels in the Cerebral Microcirculation of Genetically Hypertensive Rats: Evidence for Their Protection Against Cerebral Vasospasm by Liu, Yanping, Hudetz, Antal G, Knaus, Hans-Guenther, Rusch, Nancy J

“…The Ca K channel (KCa channel) plays a key role in buffering pressure-induced constriction of small cerebral arteries. An amplified current through this…”
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Tremorgenic Indole Alkaloids Potently Inhibit Smooth Muscle High-Conductance Calcium-Activated Potassium Channels by Knaus, Hans-Guenther, McManus, Owen B, Lee, Seok H, Schmalhofer, William A, Garcia-Calvo, Margarita, Helms, Lisa M. H, Sanchez, Manuel, Giangiacomo, Kathleen, Reuben, John P

“…Tremorgenic indole alkaloids produce neurological disorders (e.g., staggers syndromes) in ruminants. The mode of action of these fungal mycotoxins is not…”
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High-Conductance Calcium-Activated Potassium Channels in Rat Brain:  Pharmacology, Distribution, and Subunit Composition by Wanner, Siegmund G, Koch, Robert O, Koschak, Alexandra, Trieb, Maria, Garcia, Maria L, Kaczorowski, Gregory J, Knaus, Hans-Günther

“…In rat brain, high-conductance Ca2+-activated K+ (BK) channels are targeted to axons and nerve terminals [Knaus, H. G., et al. (1996) J. Neurosci. 16,…”
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Purification, Molecular Cloning, and Expression of the Mammalian sigma1-Binding Site by Hanner, Markus, Moebius, Fabian F., Flandorfer, Astrid, Knaus, Hans-Günther, Striessnig, Jörg, Kempner, Ellis, Glossmann, Hartmut

“…Sigma-ligands comprise several chemically unrelated drugs such as haloperidol, pentazocine, and ditolyl-guanidine, which bind to a family of low molecular mass…”
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The beta subunit of the high conductance calcium-activated potassium channel. Identification of residues involved in charybdotoxin binding by Hanner, M, Vianna-Jorge, R, Kamassah, A, Schmalhofer, W A, Knaus, H G, Kaczorowski, G J, Garcia, M L

“…Coexpression of alpha and beta subunits of the high conductance Ca2+-activated K+ (maxi-K) channel leads to a 50-fold increase in the affinity for…”
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Endocytic trafficking signals in KCNMB2 regulate surface expression of a large conductance voltage and Ca(2+)-activated K+ channel by Zarei, M M, Song, M, Wilson, R J, Cox, N, Colom, L V, Knaus, H-G, Stefani, E, Toro, L

“…Large conductance voltage and calcium-activated K(+) channels play critical roles in neuronal excitability and vascular tone. Previously, we showed that…”
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Glucocorticoid Regulation of Calcium-activated Potassium Channels Mediated by Serine/Threonine Protein Phosphatase by Tian, Lijun, Knaus, Hans-Guenther, Shipston, Michael J.

“…Adrenal glucocorticoids exert powerful effects on cellular excitability in neuroendocrine cells and neurons, although the underlying mechanisms are poorly…”
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Presynaptic Ca2+-Activated K+ Channels in Glutamatergic Hippocampal Terminals and Their Role in Spike Repolarization and Regulation of Transmitter Release by Hu, Hua, Shao, Li-Rong, Chavoshy, Sorush, Gu, Ning, Trieb, Maria, Behrens, Ralf, Laake, Petter, Pongs, Olaf, Knaus, Hans Gunther, Ottersen, Ole Petter, Storm, Johan F

“…Large-conductance Ca(2+)-activated K(+) channels (BK, also called Maxi-K or Slo channels) are widespread in the vertebrate nervous system, but their functional…”
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