Search Results - "H. Seifert"

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  1. 1

    Neisseria gonorrhoeae host adaptation and pathogenesis by Quillin, Sarah Jane, Seifert, H Steven

    Published in Nature reviews. Microbiology (01-04-2018)
    “…Key Points The urogenital tract is a complex environment composed of many different types of epithelial tissues and innate immune cells that sample the…”
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  2. 2

    Location, Location, Location—Commensalism, Damage and Evolution of the Pathogenic Neisseria by Seifert, H Steven

    Published in Journal of molecular biology (26-07-2019)
    “…The 10 human-restricted Neisseria species all colonize mucosal surfaces, but show a spectrum of pathogenicity. The commensal Neisseria do not normally cause…”
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  3. 3

    Above and Beyond Watson and Crick: Guanine Quadruplex Structures and Microbes by Seifert, H Steven

    Published in Annual review of microbiology (08-09-2018)
    “…Advances in understanding mechanisms of nucleic acids have revolutionized molecular biology and medicine, but understanding of nontraditional nucleic acid…”
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  4. 4

    Transcription of a cis-acting, noncoding, small RNA is required for pilin antigenic variation in Neisseria gonorrhoeae by Cahoon, Laty A, Seifert, H Steven

    Published in PLoS pathogens (01-01-2013)
    “…The strict human pathogen Neisseria gonorrhoeae can utilize homologous recombination to generate antigenic variability in targets of immune surveillance. To…”
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  5. 5

    Structured reporting of prostate magnetic resonance imaging has the potential to improve interdisciplinary communication by Wetterauer, C, Winkel, D J, Federer-Gsponer, J R, Halla, A, Subotic, S, Deckart, A, Seifert, H H, Boll, D T, Ebbing, J

    Published in PloS one (19-02-2019)
    “…Effective interdisciplinary communication of imaging findings is vital for patient care, as referring physicians depend on the contained information for the…”
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  6. 6

    The Genetics of Neisseria Species by Rotman, Ella, Seifert, H. Steven

    Published in Annual review of genetics (01-01-2014)
    “…Neisseria gonorrhoeae and Neisseria meningitidis are closely related organisms that cause the sexually transmitted infection gonorrhea and serious bacterial…”
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  7. 7

    Influence of mean stress and light water reactor environment on fatigue life and dislocation microstructures of 316L austenitic steel by Spätig, P., Heczko, M., Kruml, T., Seifert, H.-P.

    Published in Journal of nuclear materials (01-10-2018)
    “…Influence of mean stress on fatigue life of the austenitic stainless steel 316 L in air and light water environments (boiling water reactor/hydrogen water…”
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  8. 8

    Microbial antigenic variation mediated by homologous DNA recombination by Vink, Cornelis, Rudenko, Gloria, Seifert, H. Steven

    Published in FEMS microbiology reviews (01-09-2012)
    “…Abstract Pathogenic microorganisms employ numerous molecular strategies in order to delay or circumvent recognition by the immune system of their host. One of…”
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  9. 9

    Processing-Independent CRISPR RNAs Limit Natural Transformation in Neisseria meningitidis by Zhang, Yan, Heidrich, Nadja, Ampattu, Biju Joseph, Gunderson, Carl W., Seifert, H. Steven, Schoen, Christoph, Vogel, Jörg, Sontheimer, Erik J.

    Published in Molecular cell (23-05-2013)
    “…CRISPR interference confers adaptive, sequence-based immunity against viruses and plasmids and is specified by CRISPR RNAs (crRNAs) that are transcribed and…”
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  10. 10

    An Alternative DNA Structure Is Necessary for Pilin Antigenic Variation in Neisseria gonorrhoeae by Cahoon, Laty A., Seifert, H. Steven

    “…Pathogens can use DNA recombination to promote antigenic variation (Av) of surface structures to avoid immune detection. We identified a cis-acting DNA…”
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  11. 11

    DNase H Activity of Neisseria meningitidis Cas9 by Zhang, Yan, Rajan, Rakhi, Seifert, H. Steven, Mondragón, Alfonso, Sontheimer, Erik J.

    Published in Molecular cell (15-10-2015)
    “…Type II CRISPR systems defend against invasive DNA by using Cas9 as an RNA-guided nuclease that creates double-stranded DNA breaks. Dual RNAs (CRISPR RNA…”
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  12. 12

    Gonorrhoea by Unemo, Magnus, Seifert, H Steven, Hook, Edward W., Hawkes, Sarah, Ndowa, Francis, Dillon, Jo-Anne R.

    Published in Nature reviews. Disease primers (21-11-2019)
    “…The bacterium Neisseria gonorrhoeae causes the sexually transmitted infection (STI) gonorrhoea, which has an estimated global annual incidence of 86.9 million…”
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  13. 13

    The Neisseria gonorrhoeae type IV pilus promotes resistance to hydrogen peroxide- and LL-37-mediated killing by modulating the availability of intracellular, labile iron by Hu, Linda I., Stohl, Elizabeth A., Seifert, H Steven

    Published in PLoS pathogens (01-06-2022)
    “…The Neisseria gonorrhoeae Type IV pilus is a multifunctional, dynamic fiber involved in host cell attachment, DNA transformation, and twitching motility. We…”
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  14. 14

    Rapid evolution and spread of carbapenemases among Enterobacteriaceae in Europe by Cantón, R., Akóva, M., Carmeli, Y., Giske, C.G., Glupczynski, Y., Gniadkowski, M., Livermore, D.M., Miriagou, V., Naas, T., Rossolini, G.M., Samuelsen, Ø., Seifert, H., Woodford, N., Nordmann, P.

    Published in Clinical microbiology and infection (01-05-2012)
    “…Plasmid-acquired carbapenemases in Enterobacteriaceae, which were first discovered in Europe in the 1990s, are now increasingly being identified at an alarming…”
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  15. 15
  16. 16

    A bacterial siren song: intimate interactions between Neisseria and neutrophils by Criss, Alison K., Seifert, H. Steven

    Published in Nature reviews. Microbiology (01-03-2012)
    “…Key Points The pathogenic Neisseria species, Neisseria gonorrhoeae and Neisseria meningitidis , are obligate human bacteria that share many properties and…”
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  17. 17

    A Double-Strand Break Does Not Promote Neisseria gonorrhoeae Pilin Antigenic Variation by Prister, Lauren L, Xu, Jing, Seifert, H Steven

    Published in Journal of bacteriology (01-07-2019)
    “…The major subunit of the type IV pilus (T4p) of undergoes antigenic variation (AV) dependent on a guanine quadruplex (G4) DNA structure located upstream of the…”
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  18. 18

    RecA-Binding pilE G4 Sequence Essential for Pilin Antigenic Variation Forms Monomeric and 5′ End-Stacked Dimeric Parallel G-Quadruplexes by Kuryavyi, Vitaly, Cahoon, Laty A., Seifert, H. Steven, Patel, Dinshaw J.

    Published in Structure (London) (05-12-2012)
    “…Neisseria gonorrhoeae is an obligate human pathogen that can escape immune surveillance through antigenic variation of surface structures such as pili. A…”
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  19. 19

    The Pilin N-terminal Domain Maintains Neisseria gonorrhoeae Transformation Competence during Pilus Phase Variation by Obergfell, Kyle P, Seifert, H Steven

    Published in PLoS genetics (23-05-2016)
    “…The obligate human pathogen Neisseria gonorrhoeae is the sole aetiologic agent of the sexually transmitted infection, gonorrhea. Required for gonococcal…”
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  20. 20

    Transluminal endoscopic necrosectomy after acute pancreatitis: a multicentre study with long-term follow-up (the GEPARD Study) by Seifert, H, Biermer, M, Schmitt, W, Jürgensen, C, Will, U, Gerlach, R, Kreitmair, C, Meining, A, Wehrmann, T, Rösch, T

    Published in Gut (01-09-2009)
    “…As with endoscopic transmural drainage of peripancreatic fluid collections, the same transluminal access can be expanded to introduce an endoscope through the…”
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