Search Results - "H. Ralph Schumacher Jr"

Febuxostat Compared with Allopurinol in Patients with Hyperuricemia and Gout by Becker, Michael A, Schumacher, H. Ralph, Wortmann, Robert L, MacDonald, Patricia A, Eustace, Denise, Palo, William A, Streit, Janet, Joseph-Ridge, Nancy

“…In this randomized trial of patients with elevated uric acid levels and gout, febuxostat, a new nonpurine selective inhibitor of xanthine oxidase, was compared…”
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Rilonacept (Interleukin-1 Trap) in the prevention of acute gout flares during initiation of urate-lowering therapy: Results of a phase II randomized, double-blind, placebo-controlled trial by Schumacher Jr, H. Ralph, Sundy, John S., Terkeltaub, Robert, Knapp, Howard R., Mellis, Scott J., Stahl, Neil, Yancopoulos, George D., Soo, Yuhwen, King-Davis, Shirletta, Weinstein, Steven P., Radin, Allen R.

“…Objective To evaluate the interleukin‐1 inhibitor rilonacept (Interleukin‐1 Trap) for prevention of gout flares occurring in the first few months following…”
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Injectable Corticosteroids in Modern Practice by Cole, Brian J, Schumacher, H. Ralph, Jr

“…Dr. Cole is Director, Rush Cartilage Restoration Center, Rush University Medical Center, Chicago, IL. Dr. Schumacher is Chief of Rheumatology, VA Medical…”
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Randomised double blind trial of etoricoxib and indometacin in treatment of acute gouty arthritis by Schumacher Jr, H Ralph, Boice, Judith A, Daikh, David I, Mukhopadhyay, Saurabh, Malmstrom, Kerstin, Ng, Jennifer, Tate, Guillermo A, Molina, Javier

“…Abstract Objective: To assess the safety and efficacy of etoricoxib, a selective cyclo-oxygenase-2 inhibitor, in comparison with indometacin in the treatment…”
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A survey of current evaluation and treatment of gout by Naomi Schlesinger, Dirk F Moore, Jennifer D Sun, H Ralph Schumacher, Jr

“…OBJECTIVE: To record diagnostic and treatment approaches to gouty arthritis among US rheumatologists. METHODS: Questionnaires were faxed to 2500 US…”
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Febuxostat: a non-purine, selective inhibitor of xanthine oxidase for the management of hyperuricaemia in patients with gout by Schumacher, Jr, H Ralph

“…Febuxostat is a non-purine, selective inhibitor of xanthine oxidase being developed for the management of hyperuricaemia in patients with gout. With febuxostat…”
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The pathogenesis of gout by Schumacher, Jr, H Ralph

“…An elevated serum urate level, together with local factors, can result in the deposition of urate crystals into the joints. Once crystals are deposited into a…”
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The management of gout at an academic healthcare center in Beijing: a physician survey by Weigang Fang, Xuejun Zeng, Mengtao Li, Lan X Chen, H Ralph Schumacher, Jr, Fengchun Zhang

“…OBJECTIVE: Gout is a less commonly diagnosed rheumatic disease in China compared with Western countries, but its prevalence appears to be climbing. It is not…”
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Outcome measures for acute and chronic gout by H Ralph Schumacher, Jr, Lawrence N Edwards, Fernando Perez-Ruiz, Michael Becker, Lan X Chen, Daniel E Furst, Nancy Joseph-Ridge, Naomi Schlesinger, Zeb Horowitz, Kenneth Saag, Judith A Boice, Hisashi Yamanaka, OMERACT 7 Special Interest Group

“…Gout provides some unique challenges in classification and measurement of outcomes. Our aim was to evaluate criteria for classification and to develop and…”
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Local ice therapy during bouts of acute gouty arthritis by Naomi Schlesinger, Michelle A Detry, Bart K Holland, Daniel G Baker, Anna M Beutler, Marina Rull, Bruce I Hoffman, H Ralph Schumacher, Jr

“…OBJECTIVE: To evaluate the effect of local application of ice on duration and severity of acute gouty arthritis. METHODS: Nineteen patients with acute gout…”
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Tophaceous gout: quantitative evaluation by direct physical measurement by H Ralph Schumacher, Jr, Michael A Becker, William A Palo, Janet Streit, Patricia A MacDonald, Nancy Joseph-Ridge

“…OBJECTIVE: The absence of accepted standardized methods for monitoring tophaceous gout limits the ability to track tophus progression or regression. This…”
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The practical management of gout by Schumacher, Jr, H Ralph, Chen, Lan X

“…Gout management requires a comprehensive strategy that considers both acute and chronic aspects of the disease. Acute gout flares should be treated with…”
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Evaluation of glyceraldehyde-3-phosphate, prolylpeptidyl isomerase A, and a set of stably expressed genes as reference mRNAs in urate crystal inflammation by Della Beffa, Cristina, Klawonn, Frank, Menetski, Joseph P, Schumacher, Jr, H Ralph, Pessler, Frank

“…The murine air pouch membrane represents an easily accessible tissue for studies on gene regulation in acute inflammation. Considering that acute inflammation…”
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Assessing Single Joints in Arthritis Clinical Trials by KEEN, Helen I, BINGHAM, Clifton O, MEASE, Philip J, BRADLEY, Laurence A, CONAGHAN, Philip G, HEALD, Alison E, KAELEY, Gurjit S, MAKSYMOWYCH, Walter P, MOSKOWITZ, Roland W, SCHUMACHER, H. Ralph, WOODWORTH, Thasia E

“…The need to develop validated outcome measures to assess response to therapies in single joints has been recognized. In 2004, a task force was established to…”
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Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase: A twenty‐eight–day, multicenter, phase II, randomized, double‐blind, placebo‐controlled, dose‐response clinical trial examining safety and efficacy in patients with gout by Becker, Michael A., Schumacher, H. Ralph, Wortmann, Robert L., MacDonald, Patricia A., Palo, William A., Eustace, Denise, Vernillet, Laurent, Joseph‐Ridge, Nancy

“…Objective Gout affects ∼1–2% of the American population. Current options for treating hyperuricemia in chronic gout are limited. The purpose of this study was…”
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Rilonacept (interleukin‐1 trap) for prevention of gout flares during initiation of uric acid–lowering therapy: Results from a phase III randomized, double‐blind, placebo‐controlled, confirmatory efficacy study by Schumacher, H. Ralph, Evans, Robert R., Saag, Kenneth G., Clower, James, Jennings, William, Weinstein, Steven P., Yancopoulos, George D., Wang, Jian, Terkeltaub, Robert

“…Objective To evaluate the efficacy and safety of the interleukin‐1 inhibitor rilonacept (interleukin‐1 Trap) for gout flare prevention during initiation of…”
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A qualitative and quantitative analysis of the characteristics of gout patient education resources by Robinson, Philip C., Schumacher, H. Ralph

“…Patient education is an important aspect of gout management, but there is evidence that many patients lack adequate knowledge of their condition. Our aim was…”
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Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: A 28‐week, phase III, randomized, double‐blind, parallel‐group trial by Schumacher, H. RALPH, Becker, Michael A., Wortmann, Robert L., MacDonald, Patricia A., Hunt, Barbara, Streit, Janet, Lademacher, Christopher, Joseph‐Ridge, Nancy

“…Objective To compare the urate‐lowering efficacy and safety of febuxostat, allopurinol, and placebo in a large group of subjects with hyperuricemia and gout,…”
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Patient-reported Outcomes in Chronic Gout: A Report from OMERACT 10 by SINGH, Jasvinder A, TAYLOR, Will J, DABBOUS, Omar, STRAND, Vibeke, DALBETH, Nicola D, ALETAHA, Daniel, LAWRENCE EDWARDS, N, RALPH SCHUMACHER, H, SIMON, Lee S, KHANNA, Puja P, STAMP, Lisa K, MCQUEEN, Fiona M, NEOGI, Tuhina, GAFFO, Angelo L, BECKER, Michael A, MACDONALD, Patricia A

“…To summarize the endorsement of measures of patient-reported outcome (PRO) domains in chronic gout at the 2010 Outcome Measures in Rheumatology Meeting…”
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A Nice Reminder From a Former Patient to Consider Hemochromatosis as a Cause of Arthritis by Schumacher, H Ralph

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