Search Results - "H. Jayasinghe, J"
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Public sector primary care services in Sri Lanka and the specialist family physician: A qualitative study
Published in Journal of family medicine and primary care (01-11-2022)“…Introduction: In the background of a rising burden of non-communicable disease (NCD) Sri Lanka has prioritised reorganising primary care based on a family…”
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A metallothionein from disk abalone (Haliotis discus discus): Insights into its functional roles in immune response, metal tolerance, and oxidative stress
Published in Fish & shellfish immunology (01-07-2024)“…Metallothioneins (MTs) are cysteine-rich metal-binding proteins whose expression is induced by exposure to essential and non-essential metals, making them…”
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Galectin-8-like isoform X1 mediates antibacterial, antiviral, and antioxidant responses in red-lip mullet (Planiliza haematocheilus) through positive modulation of pro-inflammatory cytokine, chemokine, and enzymatic antioxidant activity
Published in Developmental and comparative immunology (01-08-2024)“…Galectin 8 belongs to the tandem repeat subclass of the galectin superfamily. It possesses two homologous carbohydrate recognition domains linked by a short…”
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Comprehensive characterization of three glutathione S-transferase family proteins from black rockfish (Sebastes schlegelii)
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01-11-2016)“…Glutathione S-transferases (GSTs, EC 2.5.1.18) are categorized as phase II enzymes, which form an important multifunctional family associated with a wide…”
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Molecular cloning, transcriptional profiling, and subcellular localization of signal transducer and activator of transcription 2 (STAT2) ortholog from rock bream, Oplegnathus fasciatus
Published in Gene (30-08-2017)“…Signal transducer and activator of transcription 2 (STAT2) is a key element that transduces signals from the cell membrane to the nucleus via the type I…”
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Molecular insights of two STAT1 variants from rock bream (Oplegnathus fasciatus) and their transcriptional regulation in response to pathogenic stress, interleukin-10, and tissue injury
Published in Fish & shellfish immunology (01-10-2017)“…Signal transducers and activators of transcription 1 (STAT1) is critically involved in mediating cytokine-driven signaling, and triggers the transcription of…”
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Molecular characterization of two immunity-related acute-phase proteins: Haptoglobin and serum amyloid A from black rockfish (Sebastes schlegeli)
Published in Fish & shellfish immunology (01-08-2015)“…Haptoglobin (Hp) and serum amyloid A (SAA) are two vital proteins involved in inflammatory reactions and are classified as acute-phase proteins. They are…”
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Three novel C1q domain containing proteins from the disk abalone Haliotis discus discus: Genomic organization and analysis of the transcriptional changes in response to bacterial pathogens
Published in Fish & shellfish immunology (01-09-2016)“…The globular C1q (gC1q) domain containing proteins, commonly referred as C1q domain containing (C1qDC) proteins, are an essential family of proteins involved…”
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A homolog of teleostean signal transducer and activator of transcription 3 (STAT3) from rock bream, Oplegnathus fasciatus: Structural insights, transcriptional modulation, and subcellular localization
Published in Veterinary immunology and immunopathology (01-04-2017)“…•Identification of STAT3 (RbSTAT3) ortholog from rock bream.•Genomic structure and putative promoter analysis of RbSTAT3.•Expression profile (In vivo) of…”
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A homolog of Kunitz-type serine protease inhibitor from rock bream, Oplegnathus fasciatus: Molecular insights and transcriptional modulation in response to microbial and PAMP stimulation, and tissue injury
Published in Fish & shellfish immunology (01-10-2015)“…Serine proteases and their inhibitors play vital roles in diverse biological processes. In this study, we identified and characterized cDNA coding for a…”
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