Search Results - "H. Abu Almaaty, Ali"
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1
Impact of Punica granatum seeds extract (PSE) on renal and testicular tissues toxicity in mice exposed to iron oxide nanoparticles (IONPs)
Published in Scientific reports (30-10-2024)“…Recently, nano-manufactured materials have been used to treat many diseases, such as healing wounds and other modern biological applications. This study…”
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2
Urtica dioica extracts abolish scopolamine-induced neuropathies in rats
Published in Environmental science and pollution research international (01-04-2021)“…Alzheimer’s disease (AD) is characterized by alterations in monoamines, oxidative stress, and metabolic dysfunctions. We aim to assess the therapeutic impacts…”
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3
Design, Synthesis, In Vitro Biological Activity Evaluation and Stabilized Nanostructured Lipid Carrier Formulation of Newly Synthesized Schiff Bases-Based TMP Moieties
Published in Pharmaceuticals (Basel, Switzerland) (28-05-2022)“…A series of novel Schiff bases-based TMP moieties have been designed and synthesized as potential anticancer agents. The target Schiff bases were screened for…”
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4
Impact of maternal desvenlafaxine exposure on brain development in pregnant albino rats and their fetuses
Published in Journal of biochemical and molecular toxicology (01-07-2022)“…Depression during pregnancy adversely affects fetal development. Desvenlafaxine drug is used for the treatment of gestational depression. In light of the…”
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5
Nomad Jellyfish Rhopilema nomadica Venom Induces Apoptotic Cell Death and Cell Cycle Arrest in Human Hepatocellular Carcinoma HepG2 Cells
Published in Molecules (Basel, Switzerland) (26-08-2021)“…Jellyfish venom is a rich source of bioactive proteins and peptides with various biological activities including antioxidant, antimicrobial and antitumor…”
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6
Statistical optimization of bile salt deployed nanovesicles as a potential platform for oral delivery of piperine: accentuated antiviral and anti-inflammatory activity in MERS-CoV challenged mice
Published in Drug delivery (01-01-2021)“…The objective of this paper is to confine piperine, a poor oral bioavailable herbal drug into bile salt based nano vesicles for improving its aqueous…”
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7
Design, Synthesis and Anticancer Evaluation of Substituted Cinnamic Acid Bearing 2-Quinolone Hybrid Derivatives
Published in Molecules (Basel, Switzerland) (04-08-2021)“…A new series of hybrid molecules containing cinnamic acid and 2-quinolinone derivatives were designed and synthesized. Their structures were confirmed by…”
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Synthesis and Biological Activity Screening of Newly Synthesized Trimethoxyphenyl-Based Analogues as Potential Anticancer Agents
Published in Molecules (Basel, Switzerland) (20-07-2022)“…A group of novel trimethoxyphenyl (TMP)-based analogues were synthesized by varying the azalactone ring of…”
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9
5-Aryl-1-Arylideneamino-1H-Imidazole-2(3H)-Thiones: Synthesis and In Vitro Anticancer Evaluation
Published in Molecules (Basel, Switzerland) (18-03-2021)“…A novel series of N-1 arylidene amino imidazole-2-thiones were synthesized, identified using IR, 1H-NMR, and 13C-NMR spectral data. Cytotoxic effect of the…”
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10
Design, Synthesis and Cytotoxic Activity Evaluation of Newly Synthesized Amides-Based TMP Moiety as Potential Anticancer Agents over HepG2 Cells
Published in Molecules (Basel, Switzerland) (20-06-2022)“…A novel series of amides based TMP moiety was designed, synthesized and evaluated for their antiproliferative as well as enzyme inhibition activity. Compounds…”
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11
Antioxidant Property of the Egyptian Propolis Extract Versus Aluminum Silicate Intoxication on a Rat's Lung: Histopathological Studies
Published in Molecules (Basel, Switzerland) (10-12-2020)“…In this study, we evaluated the inflammatory responses induced by aluminum silicate (AS) cytotoxicity in rat lungs. The prophylactic effect of propolis extract…”
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12
Design and Synthesis of Newly Synthesized Acrylamide Derivatives as Potential Chemotherapeutic Agents against MCF-7 Breast Cancer Cell Line Lodged on PEGylated Bilosomal Nano-Vesicles for Improving Cytotoxic Activity
Published in Pharmaceuticals (Basel, Switzerland) (04-10-2021)“…Cancer is a multifaceted disease. With the development of multi drug resistance, the need for the arousal of novel targets in order to avoid these drawbacks…”
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13
Evaluation of Synthetic 2,4-Disubstituted-benzo[g]quinoxaline Derivatives as Potential Anticancer Agents
Published in Pharmaceuticals (Basel, Switzerland) (26-08-2021)“…A new series of 2,4-disubstituted benzo[g]quinoxaline molecules have been synthesized, using naphthalene-2,3-diamine and 1,4-dibromonaphthalene-2,3-diamine as…”
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14
Design, Synthesis and Cytotoxicity Screening of New Thiazole Derivatives as Potential Anticancer Agents through VEGFR-2 Inhibition
Published in Symmetry (Basel) (01-09-2022)“…Z-configurated isomers are kinetically preferred molecules. Compounds with Z-configuration are contained in many natural products, biologically active…”
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15
Design, Synthesis, and In Vitro Antiproliferative Screening of New Hydrazone Derivatives Containing cis-(4-Chlorostyryl) Amide Moiety
Published in Symmetry (Basel) (01-11-2022)“…Hydrazones are regarded as a distinctive category of organic compounds because of their tremendous characteristics and potential uses in analytical, chemical,…”
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Novel Acrylate-Based Derivatives: Design, Synthesis, Antiproliferative Screening, and Docking Study as Potential Combretastatin Analogues
Published in ACS omega (17-10-2023)“…A variety of 3-(4-chlorophenyl) acrylic acids 4a,b and 3-(4-chlorophenyl)acrylate esters 5a–i were synthesized and structurally proven by spectroscopic…”
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17
Impact of Human Umbilical Cord Blood Mononuclear Cells on Gentamicin-Induced Renal Injury and Genotoxicity in Rats
Published in Frontiers in medicine (19-08-2021)“…Background: Acute kidney injury (AKI), also known as acute renal failure (ARF), has received considerable critical attention in recent years. Gentamicin (GM)…”
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18
Ameliorative Effect of Pomegranate Peel Extract (PPE) on Hepatotoxicity Prompted by Iron Oxide Nanoparticles (Fe2O3-NPs) in Mice
Published in Nanomaterials (Basel, Switzerland) (04-09-2022)“…An evaluation of the ameliorative effect of pomegranate peel extract (PPE) in counteracting the toxicity of iron oxide nanoparticles (Fe2O3-NPs) that cause…”
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19
Synthesis, characterization and anticancer investigation of some novel 2,5-disubstituted-1,3-thiazol-4-(5H)-ones and 1-substituted-1H-pyrazolo[3,4-d] thiazole derivatives
Published in Journal of molecular structure (15-02-2025)“…•2,5-Disubstituted-1,3-thiazole derivatives have been synthesized and characterized by various spectroscopy techniques.•Cytotoxic activity was approved against…”
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20
Synthesis and biological research of new imidazolone-sulphonamide-pyrimidine hybrids as potential EGFR-TK inhibitors and apoptosis-inducing agents
Published in RSC advances (18-06-2024)“…Development of new effective EGFR-targeted antitumor agents is needed because of their clinical significance. A new series of…”
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