Search Results - "H Rabbad, Ali"

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  1. 1

    Structural Insights into the Role of Pseudouridimycin Binding in Disruption of Bacterial RNA Polymerase Bridge Helix Conformational Arrangement by H Rabbad, Ali, Agoni, Clement, E Soliman, Mahmoud

    Published in Current pharmaceutical biotechnology (01-01-2023)
    “…The bridge helix (BH) is a crucial region in bacterial RNA polymerase (RNAP) catalysis. It plays an essential role in the nucleotide addition cycle (NAC) by…”
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    Journal Article
  2. 2

    PCSK9 inhibitors as safer therapeutics for atherosclerotic cardiovascular disease (ASCVD): Pharmacophore design and molecular dynamics analysis by Kehinde, Ibrahim O., Akawa, Oluwole, Adewumi, Adeniyi T., Rabbad, Ali H., Soliman, Mahmoud E. S.

    Published in Journal of cellular biochemistry (01-07-2024)
    “…Cardiovascular disorders are still challenging and are among the deadly diseases. As a major risk factor for atherosclerotic cardiovascular disease,…”
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    Journal Article
  3. 3

    Monastrol disrupts KIFC1-ATP dynamics: Towards newer anticancer mechanism by Ali, Musab, Rabbad, Ali H., Soliman, Mahmoud E.

    Published in Chemical physics impact (01-06-2024)
    “…Mitotic kinesins are eukaryotic proteins that play a vital role in cellular mitosis. Their over-expression in malignant rather than normal cells and their…”
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    Journal Article
  4. 4

    Microbes, not humans: exploring the molecular basis of Pseudouridimycin selectivity towards bacterial and not human RNA polymerase by Rabbad, Ali H., Agoni, Clement, Olotu, Fisayo A., Soliman, Mahmoud E.

    Published in Biotechnology letters (01-01-2019)
    “…Objective Bacterial RNA polymerase (bRNAP) represent a crucial target for curtailing microbial activity but its structural and sequence similarities with human…”
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    Journal Article