Search Results - "Hülsmeier, Andreas J"
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Subunit composition of the mammalian serine-palmitoyltransferase defines the spectrum of straight and methyl-branched long-chain bases
Published in Proceedings of the National Academy of Sciences - PNAS (07-07-2020)“…Sphingolipids (SLs) are chemically diverse lipids that have important structural and signaling functions within mammalian cells. SLs are commonly defined by…”
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The atypical sphingolipid SPB 18:1(14Z);O2 is a biomarker for DEGS1 related hypomyelinating leukodystrophy
Published in Journal of lipid research (01-12-2023)“…Sphingolipids (SL) represent a structurally diverse class of lipids that are central to cellular physiology and neuronal development and function. Defects in…”
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Core Glycosylation of Collagen Is Initiated by Two β(1-O)Galactosyltransferases
Published in Molecular and Cellular Biology (01-02-2009)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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4
Loss of the Bardet-Biedl protein Bbs1 alters photoreceptor outer segment protein and lipid composition
Published in Nature communications (11-03-2022)“…Primary cilia are key sensory organelles whose dysfunction leads to ciliopathy disorders such as Bardet-Biedl syndrome (BBS). Retinal degeneration is common in…”
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5
Giant mimivirus R707 encodes a glycogenin paralogue polymerizing glucose through α- and β-glycosidic linkages
Published in Biochemical journal (15-10-2016)“…Acanthamoeba polyphaga mimivirus is a giant virus encoding 1262 genes among which many were previously thought to be exclusive to cellular life. For example,…”
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Ethanol-Induced Impairment in the Biosynthesis of N-Linked Glycosylation
Published in Journal of cellular biochemistry (01-04-2014)“…ABSTRACT Deficiency in N‐linked protein glycosylation is a long‐known characteristic of alcoholic liver disease and congenital disorders of glycosylation…”
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O-Linked glycosylation in Acanthamoeba polyphaga mimivirus
Published in Glycobiology (Oxford) (01-08-2014)“…Acanthamoeba polyphaga mimivirus is a member of the giant nucleocytoplasmic large DNA viruses, infecting various Acanthamoeba spp. The genomes of giant viruses…”
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N-Glycosylation Site Occupancy in Serum Glycoproteins Using Multiple Reaction Monitoring Liquid Chromatography-Mass Spectrometry
Published in Molecular & cellular proteomics (01-12-2007)“…Congenital disorders of glycosylation (CDGs) are a family of N-linked glycosylation defects associated with severe clinical manifestations. In CDG type-I,…”
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Exposure to Mimivirus Collagen Promotes Arthritis
Published in Journal of Virology (01-01-2014)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Improvement of Dolichol-linked Oligosaccharide Biosynthesis by the Squalene Synthase Inhibitor Zaragozic Acid
Published in The Journal of biological chemistry (25-02-2011)“…The majority of congenital disorders of glycosylation (CDG) are caused by defects of dolichol (Dol)-linked oligosaccharide assembly, which lead to…”
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Characterization of mucin‐type core‐1 β1‐3 galactosyltransferase homologous enzymes in Drosophila melanogaster
Published in The FEBS journal (01-09-2005)“…Mucin type O‐glycosylation is a widespread modification of eukaryotic proteins. The transfer of N‐acetylgalactosamine to selected serine or threonine residues…”
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The Lc3-synthase gene B3gnt5 is essential to pre-implantation development of the murine embryo
Published in BMC developmental biology (12-11-2008)“…Glycosphingolipids (GSL) are integral components of mammalian cell membranes that are involved in cell adhesion and cell signaling processes. GSL are…”
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Intrahepatic Fat and Postprandial Glycemia Increase After Consumption of a Diet Enriched in Saturated Fat Compared With Free Sugars
Published in Diabetes care (01-05-2020)“…Debate continues regarding the influence of dietary fats and sugars on the risk of developing metabolic diseases, including insulin resistance and nonalcoholic…”
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Glycosylation site occupancy in health, congenital disorder of glycosylation and fatty liver disease
Published in Scientific reports (11-10-2016)“…Glycosylation is an integral part in health and disease, as emphasized by the growing number of identified glycosylation defects. In humans, proteins are…”
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Systemic acylcarnitine levels are affected in response to multiple injuries and hemorrhagic shock - an analysis of lipidomic changes in a standardized porcine model
Published in The journal of trauma and acute care surgery (01-08-2024)“…Along with recent advances in analytical technologies, TCA-cycle intermediates are increasingly identified as promising makers for cellular ischemia and…”
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Long Chain Base Profiling with Multiple Reaction Monitoring Mass Spectrometry
Published in Methods in molecular biology (Clifton, N.J.) (2025)“…Sphingolipids (SLs) are essential lipids with important functions in membrane formation and cell signaling. The presence of a long chain base (LCB) structure…”
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Apolipoprotein M and Sphingosine-1-Phosphate Receptor 1 Promote the Transendothelial Transport of High-Density Lipoprotein
Published in Arteriosclerosis, thrombosis, and vascular biology (01-10-2021)“…Objective: ApoM enriches S1P (sphingosine-1-phosphate) within HDL (high-density lipoproteins) and facilitates the activation of the S1P1 (S1P receptor type 1)…”
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18
Altered CSF Albumin Quotient Links Peripheral Inflammation and Brain Damage in MS
Published in Neurology : neuroimmunology & neuroinflammation (01-03-2021)“…CNS damage can increase the susceptibility of the blood-brain barrier (BBB) to changes induced by systemic inflammation. The aim of this study is to better…”
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Mimivirus Collagen Is Modified by Bifunctional Lysyl Hydroxylase and Glycosyltransferase Enzyme
Published in The Journal of biological chemistry (23-12-2011)“…Collagens, the most abundant proteins in animals, are modified by hydroxylation of proline and lysine residues and by glycosylation of hydroxylysine. Dedicated…”
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Proteolytic fragments of ovalbumin display antimicrobial activity
Published in Biochimica et biophysica acta (03-05-2004)“…Ovalbumin, one of the major proteins present in avian egg white, was proteolytically digested by trypsin and chymotrypsin and the peptide fragments were…”
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